摘要:

Seminal properties in relation to fertility were studied in 14 semen donors, used for heterologous inseminations in 178 women. There were 100 conceptions. Fertility of the donors was statistically significantly related to the in vitro penetration and duration of motility of spermatozoa in cervical mucus.

ISSN:0001-6349    

DOI:10.3109/00016347309158296

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

74 cases of ovarian carcinoma diagnosed and treated at the department of obstetrics and gynaecology, Helsingborg's hospital during the years 1956‐1965 were examined with special reference to the effect of various biological, social and clinical factors on the later course. The following features were associated with a more favourable prognosis: younger age groups; married women; high haemoglobin values; short duration of symptoms; uterine bleeding as first symptom; low stage of tumour; mucinous cystocarcinoma; and following tumour characteristics: unilateral tumour; unruptured tumour; non‐adherent tumour; absence of metastases; absence of ascites. The differences regarding the 5‐year survival rate were found to be statistically significant within the groups relating to age, haemoglobin value, stage and the variables given under “tumour characteristics” (with the exception of “unruptured tumour”). The patient's parity and the size of the tumour was of little or no prognostic value in the present series. The prognosis was significantly better for patients who had bilateral oophorectomy combined with hysterectomy, than for those who had bilateral oophorectomy alone. The total 5‐year survival rate was 35.1%. 6‐16 years after the diagnosis 29.7% of the patients were still alive, 5.4% had died from intercurrent diseases and 64.9

ISSN:0001-6349    

DOI:10.3109/00016347309158297

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

The results of intravenous pyelography (IVP) and radioisotope renography (RNG) were compared pre‐ and postoperatively in 77 patients with carcinoma of the cervix. A comparison was made of the occurrence of obstructive uropathy. A total of 161 comparisons between the two tests were done. The results revealed that the IVP never was abnormal without the RNG also being so. The data suggest that radioisotope renography to a large extent can replace intravenous pyelography in the evaluation of gynecological patients after operatio

ISSN:0001-6349    

DOI:10.3109/00016347309158298

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

605 samples of amniotic fluid were obtained by abdominal amniocentesis in 363 late pregnancies. The liquor was analysed with respect to ΔE450(the optical density at 450 nm), progesterone and total protein content. On 172 samples measurements of the acid and alkaline phosphatase activity were also performed. Most of the samples came from pregnancies complicated by isoimmunization, but the material also contained samples from women with hepatosis gravidarum or other complications as well as from normal pregnancies. The measurements have been studied in relation to duration of pregnancy, cord blood haemoglobin levels, cord serum bilirubin levels, infant birth weight, maternal serum bilirubin levels, maternal alkaline phosphatase levels, maternal age, order of pregnancy, maternal and infant blood groups. For part of the series the relationships between the parameters were studied by multiple regression analysis. The results indicate a rather weak correlation between infant cord blood haemoglobin levels and the other parameters. The ABO blood groups of mother and infant influence the levels of cord blood haemoglobin, cord serum bilirubin and amniotic fluid total protein. Amniotic fluid progesterone and ΔE450values are correlated to amniotic fluid total protein levels. Low ΔE450values indicate that the fetus is mature. Determinations of ΔLE460before the 37th week show a better correlation with the condition of the infant than later ones. Order of pregnancy influences the total protein content of amniotic fluid in normal pregnancies. Determinations of acid and alkaline phosphatases in amniotic fluid do not give any clinically important information in cases of isoimmunization. Meconium contamination strongly increases alkaline phosphatase activity. Attempts to use the rapid method ofBrownfor oestrogen determinations in amniotic fluid proved to be difficult for technical reas

ISSN:0001-6349    

DOI:10.3109/00016347309158299

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

A method for the continuous recording of uteroplacental blood volume has been described. A radioactive isotope (γ emitter) which is retained in the blood stream is injected into a cubital vein and the organ is surveyed externally using a γ detector. The activity measured is directly proportional to the blood volume surveyed by the detector. The method is satisfactory for organs with a large blood volume compared to that of the tissues intervening between organ and detector. Therefore uteroplacental blood volume changes can be compared with those of other organs. Applications of the method in diagnosis and therapeutics have been discusse

ISSN:0001-6349    

DOI:10.3109/00016347309158300

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

On the basis of numerous biopsy specimens of the endometrium, in which substrates and enzymes concerned in the metabolism of glucose were examinedin vitro, the following observations were made. Respiration and redox capacity as well as endogenous and exogenous glycolysis of the endometrium are increased maximally during the secretory phase. In this phase also the absolute Pasteur effect is increased to a maximum, while the control of glycolysis by the substrate is decreased. In addition, a Crabtree‐effect appears at the same time. This suggests that the endometrium in the implantation phase endeavours to deliver constant amounts of ATP and to maintain a stable physico‐chemical environment. While, from a gynaecological point of view various endometrium‐associated disorders cause no notable differences in metabolism, the uptake of glucose, or respiration, cytochrome oxidase and succinate dehydrogenase activity in the secretory endometrium decrease with advancing age and thereby presumably diminish the fertility of the elderly woman. The use of oral contraceptives reduces the glucose metabolism from endogenous and from exogenous substrates in the endometrium, despite increasing synthesis of glycogen during the cycle. The reduction of metabolism occurs to such an extent that it must be expected that a contraceptive effect in the endometrium takes

ISSN:0001-6349    

DOI:10.3109/00016347309158301

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Determinations were made of fibrin degradation products (FDP) in serum from 19 patients who were receiving radiotherapy after the surgical treatment of malignant ovarian tumours. FDP decreased or disappeared in association with operation and radiotherapy but increased or re‐appeared with recurrences. Possible explanations of this phenomenon are discusse

ISSN:0001-6349    

DOI:10.3109/00016347309158302

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Percutaneous nephropyelostomy as a therapeutic method in postrenal obstruction is evaluated in a series of 44 cases. 12 of the patients had been treated for carcinoma of the cervix uteri by Wertheim's operation. 10 patients had ureteric stones with or without enclosed pyelitis. 11 patients had progressive uremia due to inoperable cancer of the pelvis with stenosed ureters. To relieve the obstruction the renal pelvis was drained for a long period of time and this maintained or improved renal function until the optimal time for definitive treatment was reached. The operation allowed repeated antegrade pyelography, and in some cases split function, to be performed. Thus the effect of the therapy could be checked repeatedly. Though we consider that the method should, as a rule, be used only temporarily, it may be used for up to 7 months as shown in Table III. The investigations cover the period 1966 to 1971.

ISSN:0001-6349    

DOI:10.3109/00016347309158303

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

In a clinical controlled trial the use of vinyl‐ether‐ether‐N2O (53 cases) and diazepam‐N2O (48 cases) as general anaesthetic for operative vaginal delivery is compared. Local anaesthetic for episiotomy was applied in both methods to enhance analgesia. In the diazepam group there were no maternal complications while in the vinyl‐ether‐ether‐group there were 14 cases of vomiting, of which 2 led to aspiration with development of Mendelsohn's syndrome. A third case in the same group also had an aspiration without evident sequelae. The time from start of anaesthetic induction till complete delivery of the baby was on average 6 min 17 sec in the vinyl‐ether‐ether group compared with 2 min 21 sec in the diazepam group, which means an average reduction of about 4 min. Diazepam anaesthesia is simple to administer, effective, allows rapid delivery and is comfortable and safe for the mother. This form of anaesthesia made the obstetrician's task easier during delivery. It also appears to be a safe method for the newborn, judged by the Apg

ISSN:0001-6349    

DOI:10.3109/00016347309158304

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

A precipitating monospecific rabbit antiserum was produced by immunization with purified “pregnancy zone” protein. By means of double diffusion in agar gel 27 out of 30 pregnant women at term and 23 out of 30 women treated with oral contraceptives were found to have the “pregnancy zone” protein in their serum. The “pregnancy zone” protein was not detectable in 30 sera from non‐pregnant women, 30 cord sera and 30 samples of amniotic fluid. A comparison between the electrophoretic and immunodiffusion methods for the detection of the “pregnancy zone” protein showed that the immunodiffusion method was about twice as sensitive as the elect

ISSN:0001-6349    

DOI:10.3109/00016347309158305

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY