摘要:

Abstract.Fetal biparietal diameter was measured in utero with ultrasonic techniques, in 1 Oil patients with 3 032 measurements at gestational ages ranging from 15 to 43 weeks. The distribution of these values, the mean weekly increments, together with the 5th to 95th percentiles are presented in tabular and graphic forms. The mean values correspond to those quoted in other investigations.

ISSN:0001-6349    

DOI:10.3109/00016347309158314

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.The blood flow in the lower legs of 68 primi‐gravidae was examined plethysmographically, by which a measure of mainly the muscle flow was obtained. The subjects were divided into three groups according to duration of pregnancy, and the blood flow at rest and during reactive hyperaemia was recorded. The periods of pregnancy were 9–13 weeks (Group A), 15–22 weeks (Group B) and 37–42 weeks (Group C). Subjects in Group A were examined 1 day, 2 weeks and in a few cases 8 weeks after abortion in addition to examination during pregnancy: subjects in Groups B and C were examined 2 weeks after abortion and delivery respectively. The blood flow at rest during pregnancy, expressed in ml/min × 100 ml tissue was lower in Group C than in Groups A and B. During reactive hyperaemia the blood flow did not differ significantly between the three groups. In early pregnancy the muscular blood flow does not seem to increase in comparison with the nonpregnant state. The increased cardiac output during early pregnancy thus does not seem to pass through the muscles of the limbs. During the latter half of pregnancy resting blood flow measured with the subject in the supine position decreases, which is contrary to earlier

ISSN:0001-6349    

DOI:10.3109/00016347309158315

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Fertility, pre‐freeze and post‐thaw sperm motility, penetration ability and duration of motility in cervical mucus of spermatozoa were studied in 7 heterologous insemination donors and in 4 men in connection with homologous inseminations. No conception occurred after 50 heterologous and 15 homologous inseminations using semen preserved at—196°C. The post‐thaw motility, penetration ability and duration of motility in cervical mucus of spermatozoa were reduced by the freeze‐preservation procedure. The fertilizing capacity of freeze‐pre‐served semen was more reduced than expected from the post‐thaw sperm motility and penetration ability. The semen quality was of significant importance for the post‐thaw sperm motility and p

ISSN:0001-6349    

DOI:10.3109/00016347309158316

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.A survey has been made of all invasive moles and gestational choriocarcinomata registered during a 30‐year period in Denmark, a nation with a population of about 5 million (1971). All the diagnoses have been verified histologically by reappraisal. Based on clinical data the 2 groups of patients are described with reference to the following criteria: incidence and age; gravidity, parity, and latency; dissemination and course of disease; and treatment. Some case histories are reported which contrast with the view generally prevailing before the era of chemotherapy, viz. that choriocarcinoma was a highly malignant and rapidly progressive disease. All the 19 patients who had an invasive mole, including 5 with metastases, became free from symptoms, and transition from this lesion to choriocarcinoma did not occur in any of these cases. Among the 50 choriocarcinoma patients the over‐all mortality was 64%; 18 patients (36%) —10 of them with metastases—recovered. A decreasing mortality was observed during the period under investigation, but much additional work has to be done before the prognosis of the disease approaches that of invasive mole. In conclusion, the results of this study illustrate the many difficulties encountered in the diagnosis, treatment and follow‐up of these rare trophoblastic tumours. The need for collaboration in prospective cases and for centralized treatment is strongly indicated from scientific as well as therapeutic point

ISSN:0001-6349    

DOI:10.3109/00016347309158317

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.The effect of low‐dose gestagen pills on hepatic function was investigated in 5 subjects who had previously suffered from hepatosis of pregnancy and 9 healthy controls. The gestagen used was 0.3 mg of norethisterone daily. The following laboratory tests were performed during the 6 months of low‐dose gestagen medication: Serum alanine aminotransferase (S‐ALAT‐GPT), serum cholesterol, triglycerides, total bilirubin, total proteins, electro‐phoretic distribution of proteins, α‐1‐antitrypsin, cerulo‐plasmin, acid α‐1‐glycoprotein, α‐2‐HS‐glycoprotein, total haptoglobin, β‐lipoproteins, α‐2‐macroglobulin, transferrin, and IgG immunoglobulin. The tests either revealed no differences between the two groups or showed only minor changes. None of the subjects discontinued the treatment because of hepatic dysfunction or symptoms suggestive of such. The authors consider oral contraceptives containing low doses of gestagen to be suitable even for patients who have

ISSN:0001-6349    

DOI:10.3109/00016347309158318

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.The absorption of trimethoprim‐sulfonamide combination into serum and transfer to the amniotic fluid after oral and intravaginal administration was studied on 134 patients undergoing legal abortion. The combination given orally as a single dose was absorbed rapidly: the peak levels of both trimethoprim and sulfamethoxazole in serum were reached within 4 hours. In amniotic fluid, the peak level of trimethoprim appeared within 14 hours and that of sulfamethoxazole within 10 hours. After a single intravaginal application of cream, the absorption of trimethoprim into serum and transfer to the amniotic fluid was smaller although measurable amounts could be demonstrated. After repeated intravaginal application during several days no accumulation of trimethoprim in serum or amniotic fluid could be detecte

ISSN:0001-6349    

DOI:10.3109/00016347309158319

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Systolic and diastolic blood pressure, urinary protein and amount of edema were compared with factors reflecting the prognosis and condition of the newborn in a series of 4404 patients with EPH‐gestosis, collected from the Helsinki University Central Hospital in 1965–1969 and the University Women's Clinic, Würzburg, in 1960–1969. No significant association was observed between slight and moderate edema and the prognosis of the newborn. The systolic blood pressure gave more significant information than the diastolic blood pressure. The amount of urinary protein showed the most consistent correlation with an impaired prognosis. The systolic blood pressure and proteinuria were thus the most significant indicators. An index for estimation of the prognosis in EPH‐gestosis was constructed on this basis. The purpose of this index is to provide a means of assessing the severity of the condition in the initial stage of treatment by exact use of simple observations. The index defines the risk of perinatal mortality, prematurity, asphyxia and smallness for dates in the individ

ISSN:0001-6349    

DOI:10.3109/00016347309158320

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Information derived from the compulsory national scheme of medical registration of births in Norway has been utilized in a study of the course and outcome of pregnancy in women with epilepsy. The series comprises 371 pregnancies in women with epilepsy and, as controls, 112530 pregnancies in women reporting no disease before or during the pregnancy. Comparisons indicate that women with epilepsy experience an excess of complications during pregnancy and labour, and that their babies are more frequently born prematurely and of low birth weight, and moreover have an excess of congenital malformations and higher perinatal and neonatal mortality rates. Epileptics, undoubtedly, constitute a high risk group in need of special attention during pregnancy and special care during labour. A proper interpretation of the findings in terms of causation, however, will call for additional data obtainable only through especially designed inquiries.

ISSN:0001-6349    

DOI:10.3109/00016347309158321

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Fetal cephalometry with pulsed ultrasound (A and B scan) has been performed in 35 patients with pre‐eclampsia. A classification of fetal growth retardation was based on standard tables for newborn infants. The biparietal diameters were generally small in growth‐retarded fetuses, both in relation to fetuses of normal weight in pre‐eclamptic mothers, and in relation to the average measurements in a previously compiled group of normal pregna

ISSN:0001-6349    

DOI:10.3109/00016347309158322

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Histological “dating” of endometrial biopsy specimens within the postovulatory period was performed in a group of normal women having an I.U.D. and another group of normal women without an I.U.D. In both groups the time of ovulation was determined by basal temperature measurement. By comparing the “histological” date with the actual point of time in the cycle, given in days after the ovulation, the group of women with an I.U.D. showed an average retardation of 2 days. In the control group the average retardation was zero days. The difference between the two groups was statistically significant. The group with an I.U.D. presented focal stromal changes, which should be investigated further with a view to a possible endocrine secretion. The results of the present investigation of a fairly small series show that the contraceptive effect of an I.U.D. may be due to delayed endometrial deve

ISSN:0001-6349    

DOI:10.3109/00016347309158323

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY