摘要:

A retrospective investigation of 641 live infants weighing less than 2 500 g showed that the frequency of a low Apgar score (≤7, five minutes after birth) was significantly correlated to the birth weight of the infant and independent of the mode of delivery and the presentation of the fetus at birt

ISSN:0001-6349    

DOI:10.3109/00016348609158220

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Sexual function and somatopsychic reactions were examined in 25 women following vulvectomy and in 15 of their partners. More than half of the women had both sexual dysfunction and psychological problems. Their partners had no sexual dysfunction but almost half had psychological problems. An important reason for this seems to be insufficient information and advice both pre‐ and postope‐ratively and failure to recognize a developing stricture of the introitus vaginae. Frequent control and advice to both partners both pre‐ and postoperatively is desirable. Less extensive surgical procedures in selected cases should be consi

ISSN:0001-6349    

DOI:10.3109/00016348609158221

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Serum cholic acid (CA), chenodeoxycholic acid (CDCA) and other biochemical markers of liver diseases were determined during pregnancy and in the puerperium in 19 normal and 16 pre‐eclamptic women. In one‐third of the cases, either CA or CDCA or both increased to values above the reference limits 6 weeks after deliv

ISSN:0001-6349    

DOI:10.3109/00016348609158222

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Iron, zinc and folate statuses of 45 women were determined during pregnancy around 12, 20, 28, 32 and 36 weeks, and again 2 months after delivery. Analyses of plasma ferritin, Hb, MCV, folate and zinc in plasma and whole blood were performed. Iron supplementation was recommended from mid‐pregnancy but 13 of the participants did not use the iron supplements. This group had significantly decreased levels of plasma ferritin and MCV at the end of pregnancy, but none developed anemia. Two months post partum the plasma ferritin of the unsupplemented group had normalized and was in the same range as in the supplemented group. The concentrations of zinc in plasma and whole blood and the calculated levels of red cells were low even at the first examination around 12 weeks of gestation, compared with non‐pregnant women. Throughout the course of pregnancy the plasma zinc levels continued to decrease, while the whole blood and red cell levels showed a significant rise. At term of gestation almost half the women had subnormal plasma folate levels (L. casei), which persisted during the post partum follow‐up. The corresponding value for red cell folate was 10% below normal values at term and 30% subnormal 2 months after parturition. These findings stress the importance of extending the observation period to include also the lactating period, in order to judge the need for folate supplement

ISSN:0001-6349    

DOI:10.3109/00016348609158223

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

The effects of prolonged intravenous infusions of cholic acid into fetal lambs are described in this study. The ewes (n = 10, 11 fetuses) were operated on at 114 days of gestation (term = 150 days) by placing plastic catheters in maternal and fetal vessels and in the amniotic cavity. Gestational ages were confirmed after delivery by radiographic examination of the ossification centers of the fetal legs. Infusions of cholic acid (1.6 μmoles/min−1) started 8 to 10 days after surgery in 5 fetuses (including one twin). The remaining 6 fetuses (also including one twin) were infused with 5% dextrose in water.Total plasma bile acids at the beginning of the experiment were similar in both groups (23.8±6.6 vs. 24.3±5.7 μM). No significant changes in fetal heart rate, blood pressure, blood gases or pH were detected during the infusion.Meconium‐stained amniotic fluid was observed during the third day of infusion in all the fetuses infused with cholic acid and in one control fetus. Fetuses infused with cholic acid were delivered alive 19–26 days before term. The concentration of plasma bile acids in the experimental group at delivery was 829±305 μM, i.e. significantly higher than that of the control group (24.4±5.7 μM). Control fetuses (except one twin) were delivered at term.We concluded that cholic acid, even at the high dose infused, is neither lethal nor severely harmful for the fetus. Meconium passage of the fetuses infused with cholic acid, in our experiment, appeared to be related to the stimulatory effect of cholic acid on fetal colonic motility rather than to fetal hypoxia. The cause of premature labor in the ewes with fetuses infused with cholic acid is not evident from the results of the presen

ISSN:0001-6349    

DOI:10.3109/00016348609158224

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Late amniocenteses (>20 weeks' gestation) were performed in 114 pregnancies with noa priorigenetic risk, but referred because of abnormal clinical and/or ultrasound findings suggesting fetal malformations. Reasons for referral included polyhydramnios (51 cases), oligohydramnios (15 cases), fetal growth retardation (FGR) (16 cases) and abnormal fetal ultrasound findings excluding anencephaly (32 cases). In 42 of these cases, referral was motivated by a combination of the above abnormal findings. When polyhydramnios was the sole anomaly (25 cases), 5 fetuses were malformed (20%), abnormal fetal karyotype and/or elevated amniotic fluid alphafetoprotein (AFP) were demonstrated in 2 cases. Oligohydramnios was the sole anomaly in one case; the infant died of prematurity. Fetal growth retardation was the sole anomaly in 14 cases, 11 otherwise normal newborns were small for date, 2 died at birth and 1 was malformed (1/14, 7%). In this group all fetal karyotypes were normal and in 2 cases amniotic fluid AFP were increased. In the 32 pregnancies without abnormal amniotic fluid volume and/or FGR and with fetal malformation(s) suggested by ultrasound, all malformations except one (ovarian cyst possibly ruptured during birth) were confirmed at birth, amniotic fluid AFP was elevated, and/or karyotype was abnormal in 6 cases. In 42 pregnancies where more than one alarm sign was present, abnormal karyotype and/or elevated amniotic fluid AFP level were recorded in 21 of the 39 cases where amniocentesis was performed, 33 fetuses were malformed (79%) and 13 died in the perinatal period (31%). The high incidence of abnormal results of amniocentesis found in this survey of pathological pregnancies, particularly in those with multiple alarm signs, emphasizes the need for amniocentesis in these situations.

ISSN:0001-6349    

DOI:10.3109/00016348609158225

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

The action of oral contraceptives (OC) (50 μg ethi‐nylestradiol + 250 μg levonorgestrel) on plasma and platelet lipid composition was studied in two groups of women who took this OC for one year, or for a longer period of time (2–9 years). Comparison with the control group showed that the ingestion of OC modifies the composition of some fatty acids in plasma and platelets. This modification is more marked in the women who took OC for one year. In plasma a decrease in linoleic acid (18:2) was found in the cholesterol and phospholipid fractions. In platelets, an increase of stearic acid (18:0) was observed in phospholipids, triglycerides and free fatty acid fractions. The modifications observed in plasma and platelets were not parellel, which suggests a specific and different action of OC on both plasma and platelets. Finally, it is suggested that the lipid variations found in the group that took the OC for one year may be compatible with a platelet hyperfun

ISSN:0001-6349    

DOI:10.3109/00016348609158226

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Histopathological findings in 226 post‐meno‐pausal bleeding women were reviewed retrospectively. Ade‐nocarcinoma of the endometrium was diagnosed in 7% and hyperplastic endometrium in 15%. The incidence of malignancy showed a definite rise with advancing age, increasing amount and duration of bleeding, prolonged time interval between the menopause and onset of bleeding, and enlarged uterus. Adenocarcinoma of the endometrium was associated in 40% of the patients with either obesity, diabetes mellitus, or hypertension. The most frequent histopathological finding was atrophic endometrium

ISSN:0001-6349    

DOI:10.3109/00016348609158227

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

A synchronous relationship between the menstrual cycle and lunar rhythm was confirmed by1. Investigative data: Among the 826 female volunteers with a normal menstrual cycle, aged between 16 and 25 years, a large proportion of menstruations occurred around the new moon (28.3%), while at other times during the lunar month the proportion of menstruations occurring ranged between 8.5–12.6%; the difference was significant (p<0.01).2. Laboratory findings: The 6‐hydroxymelatonin levels in the urina sanguinis of 3 female volunteers reached their zenith prior to and during menstruation, gradually declining to their nadir during ovulation. The difference in 6‐hydroxymelatonin between menstruation and ovulation was significant (p<0.01). Two of these three volunteers had their zenith in the period of the new moon and nadir 3—4 days prior to the full moon respectively.3. Clinical experience: The lunar‐menses‐regulatory therapy in treatment of Nephropenic secondary amenorrhea revealed 4 clinical cure, 5 marked effect, 8 menogogue and 3 inef‐fect ou

ISSN:0001-6349    

DOI:10.3109/00016348609158228

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

In a study involving 176 males attending an infertility clinic and 88 controls awaiting elective vasectomy, the semen acid phosphatase activity was found to be significantly higher in the former group (p<0.001). However, no definite relationship of semen acid phosphatase level to ejaculate volume, sperm motility, viability, morphology, seminal zinc, magnesium or fructose was observed in either group. The distribution of acid phosphatase in the males attending the infertility clinic, unlike that of the controls, was found to be bimodal. 32 presumably infertile males had acid phosphatase values exceeding the control mean±2 SD. These 32 nevertheless did not have a significantly different mean ejaculate volume, sperm motility, morphology or viability, when compared with the group with normal acid phosphatase levels. Causes of the bimodal distribution of concentrations of acid phosphatase are discussed

ISSN:0001-6349    

DOI:10.3109/00016348609158229

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY