摘要:

Abstract.After observing 2 cases of isolated torsion of the Fallopian tube, we inquired of all surgical and gynaecological departments on the Danish islands of Zealand and Lolland–Falster whether any such cases had been treated during the period 1957–1967. In this way we traced another 8 cases. As the departments concerned serve an area of Denmark with a population of about 3 millions, about half of whom are women, the annual incidence of isolated torsion of the Fallopian tube may be estimated as one in 1,500,000 women. The 10 case histories are briefly reported. Some theories on the aetiology of tubal torsion are mentioned, and the symptoms as well as treatment are discus

ISSN:0001-6349    

DOI:10.3109/00016347009157506

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.Detection of tumour cells in cervicovaginal secretions nearly always indicates the presence of a malignant tumour or epithelial dysplasia. Presence of suspicious cells or cells with atypical nuclei very often suggests the existence of a malignant tumour or epithelial dysplasia (46 and 14%, respectively). The great majority of the remaining patients with such cytological changes suffer from other gynaecological diseases, most often of an inflammatory nature. A cytologic differentiation between these groups is not yet possible. Other examinations are therefore indicated. Cytological changes in the cervicovaginal secretion rise in frequency with increasing age. In 9% of the patients with carcinoma of the cervix no abnormal cells were detected in the cervicovaginal secretions. The corresponding figures for severe (“carcinoma in situ”) and moderately severe epithelial atypia were 22 and 31%, respectively. No more than one third of the patients with carcinoma of the uterine body had abnormal cytology. Hence, on the slightest suspicion of malignancy we should not rely on a “negative cytology”, and especially not as the result of a single examination.Carcinomas of the uterine body generally manifest themselves by bleeding disorders. The diagnosis is to be established on the basis of curettage.In the present series the cytologic examination decided the diagnosis and treatment in no more than a single case of cervical carcinoma. Cytologic examination therefore seems to be of limited value for patients admitted to a gynaecological unit, where other diagnostic aids are available. On the other hand, the method is believed to be of value in practice, when we bear in mind that, like other methods, it is vitiated by a certain margin of error. On the slightest clinical suspicion of a malignant or premalignant disease we should not rest content with a single negative exam

ISSN:0001-6349    

DOI:10.3109/00016347009157507

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.One hundred women with acute vaginal discharge were examined clinically, cytologically and virologically for herpes simplex. Eleven of them showed cytological signs of herpes simplex, a diagnosis that was confirmed virologically in 5. This frequency of cytological and virological changes is much higher than that found in routine smears. Gynaecological examination showed signs of herpes genitalis in only 3 cases.

ISSN:0001-6349    

DOI:10.3109/00016347009157508

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.The part played by genital tuberculosis, salpingitis isthmica nodosa and endometriosis tubae interna in the formation of diverticula of the Fallopian tube is discussed. The author supports the view that a radiographic differential diagnosis between the latter two conditions is not possible. A case is described in which a diverticulum of the middle portion of the Fallopian tube was revealed by hysterosalpingography in a patient, aged 28 years. She had a history of two episodes of salpingitis, two spontaneous abortions and of a tubal pregnancy on the right side which was treated by excision of the fimbriated end of the right tube. The radiographic appearance of the lesion did not resemble those of the diverticula seen in salpingitis isthmica nodosa, endometriosis tubae interna or genital tuberculosis. The genesis of the lesion could not be determined with certainty.

ISSN:0001-6349    

DOI:10.3109/00016347009157509

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.Tissue from 35 patients with invasive squamouscell cancer of the cervix uteri at different clinical stages was transplanted intraperitoneally, in 300 diffusion chambers into 300 castrated and non‐castrated female rats.The chambers were removed within 10 days. The contents of the chambers were fixed in 5% formalin and subjected to the usual methods of histological preparation, with staining by haematoxylin‐eosin. Filters with tissue cultures were fixed in 95% ethanol and then stained with haematoxylin‐eosin.The cultures were found to contain growth of epithelial and stroma elements. The epithelial proliferation was found to be increased in the neighbourhood of the fibroblasts. The rate of proliferation did not depend on the clinical stage of the cancer.Microbodies or blebs were found around the cell nucleus in varying numbers. The greatest number was found in cancer from clinically advanced cases. The nature of these microbodies has not been clarified, but they are in the course of being investi

ISSN:0001-6349    

DOI:10.3109/00016347009157510

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.This is a report of a 28‐year‐old woman with cholestasis occurring in the first month of gestation in four consecutive pregnancies. During the interval between the third and fourth pregnancy as well as during and after the fourth one the patient was regularly examined with regard to her liver function. Intensive itching and markedly elevated serum bile acids were the predominant symptom and laboratory finding during the fourth pregnancy. Both decreased during cholestyramine treatment. The bromsulphalein retention was quite normal six months after the third pregnancy but is still elevated two and a half years after the last

ISSN:0001-6349    

DOI:10.3109/00016347009157511

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A patient is described with primary amenorrhoea, elevated urinary pregnanediol and pregnanetriol and diminished aldosterone excretion and with clinical signs of hypooestrogenism, but without signs of virilization. Sequential stimulation by large doses of human menopausal and chorionic gonadotrophins resulted in the formation of several Graafian follicles and fresh corpora lutea. These morphological changes were not accompanied by any clinical signs of an increased oestrogen secretion or by an increased urinary oestrogen excretion. Tracer studies revealed that the patient was capable of carrying out a 17α‐hydroxylation, but not the removal of the steroid side‐chain. It is concluded that ovulation and corpus luteum formation in women are not dependent on a concomitant oestrogen synthesis by the maturing foll

ISSN:0001-6349    

DOI:10.3109/00016347009157512

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A new haemostatic agent POR‐8, a synthetic derivative of vasopressin, has been investigated under double blind trial conditions. It was found to be an effective haemostatic, significantly better than noradrenalin. Fully satisfactory haemostasis was obtained after local infusion of POR‐8 in such low concentration as 0.05 IU/ml. The risk of cardiac arrhythmias when POR‐8 is used with halothane appears to be mi

ISSN:0001-6349    

DOI:10.3109/00016347009157513

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A series of 289 patients with primary ovarian cystadenocarcinomas is presented. Of the tumours, 183 were of the serous and 106 of the pseudomucinous type. The total number includes 41 borderline serous and 18 borderline pseudomucinous cystadenocarcinomas. In this series the survival rates were the same in pseudomucinous and serous cystadenocarcinomas. From the standpoint of survival rates there seemed to be no difference between bilateral and unilateral cases of stage I. No statistically significant difference was observed either, with regard to the survival rates in cases of adherent and nonadherent tumours of stage I, although there seemed to be a tendency towards more favourable results for the non‐adherent carcinomas. On evaluating the results from the standpoint of treatment, irradiation seemed to be of no use in cases in which the tumour was limited to the ovaries. The benefit of radiotherapy is questionable also in those cases where it is sure that the entire tumour has been successfully removed. On the other hand, in cases of widespread carcinoma the value of radiotherapy seems to be indisputabl

ISSN:0001-6349    

DOI:10.3109/00016347009157514

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.Daily painting of the umbilical stump with Betadine®3during the stay in the maternity ward reduced the incidence of umbilical infections. In clinical use a tiny rubber ring for closure of the cut umbilical cord proved more practical and cheaper than a clip, the use of the ring in conjunction with painting with Betadine® accelerated the separation of the stum

ISSN:0001-6349    

DOI:10.3109/00016347009157515

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY