摘要:

AbstractCollagen from the chorioamnion units from premature and term pregnancies was solubilized by limited pepsin digestion and subjected to SDS‐PAG electrophoresis. Collagen types were quantitated by densitometry. It was found that collagen type III decreases and collagen type V tends to increase as gestational age advances. Investigating the relative abundance of collagen types at various membrane sites from term pregnancies revealed that type V decreases in the amnion as the rupture site is approached. It is concluded that since type V collagen is more resistant to collagenases, its decrease may predispose that particular site to ruptur

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07801.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractThe cerebral function monitor, a system which records integrated electroencephalograms, was used to assess neurological status of newborns who had a non‐reactive non‐stress test prior to delivery. Babies born within 24 h of a non‐reactive tracing had a significant lack of sleep cycling and persistence of immature patterns when compared with controls matched for gestationa

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07802.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractLysine vasopressin and a long‐acting analogue Nα‐triglycyl‐lysine vasopressin were compared in a prospective randomized double‐blind study including 71 women undergoing cold knife conization of the uterine cervix. Hemodynamic and hemostatic variables were studied. Nα‐triglycyl‐lysine vasopressin had the following advantages over lysine vasopressin: it gave significantly less skin pallor, becoming evident at a later stage during the operation. The diastolic blood pressure was significantly lower, as also was the incidence of postoperative hemorrhages. Factor VIII related antigen was lower. On the other hand reduction in heart rate (values before conization compared with values during conization) was more pronounced when Nα‐triglycyl‐lysine vasopressin was used, but there was no difference in absolute values between the two groups

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07803.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractThirty‐four women with normal menstrual cycles but suffering from severe premenstrual mastalgia were randomly treated with either tamoxifen (10 mg daily) (18 women) or placebo (16 women) from cycle day 5 to 24 for six consecutive cycles. At the end of the treatment, 89% of the tamoxifen‐treated patients were free from the symptoms and the remainder experienced partial alleviation. In contrast, six patients treated with placebo showed only partial alleviation (38%)(p<0.001). Twelve months after the end of tamoxifen treatment, 53% of the medicated women were still free of symptoms as compared with none of the placebo‐treated patients. These results suggest that tamoxifen is highly effective for the management of severe premenstrual mastalgia and should be useful for the treatment of this dis

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07804.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractThe anti‐estrogenic effect of clomiphene citrate (CC) and tamoxifen (TMX) on cervical mucus was evaluated in a prospective crossover study. Ten women underwent randomized alternate cyclical treatment with either 100 mg CC, 40 mg TMX daily, or with placebo. The effect of CC, TMX and placebo on serum estradiol (E2), cervical mucus secretion and on the development of ovarian follicles was evaluated. Compared with placebo, treatment with CC and TMX significantly increased the number of mature ovarian follicles on the day of assumed ovulation (p<0.05), elevated E, secretion (p<0.05) and decreased cervical score (p<0.05). It can be concluded that anti‐estrogenic agents reduced the secretion of cervical mucus. However, in most cases, the excessive E, production due to multiple follicular growth overcomes the anti‐estrogenic e

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07805.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractTwenty‐five women with complete perineal rupture were compared with a control group of 25 women, with regard to risk factors and possible long‐term sequelae as a consequence of perineal damage. Following an average period of 78 months (52—‐1231, all women received a questionnaire and were invited to a clinical follow‐up, which included perineal inspection and measurement of the anal pressure profile. Vacuum extraction was more frequent in the rupture group than among controls (p<0.002). Eighty percent of the women in the rupture group were primiparae, compared with an overall rate of 40% (p<0.02). Forty‐two percent of the women in the rupture group reported anal incontinence, compared with none in the control group (p<0.01). Most of these women reported stress‐provoked incontinence regarding flatus and loose stools. Measurement of the anal pressure profile showed markedly reduced sphincter pressure, with maximum squeeze in the rupture group, but no differences were found regarding maximum anal pressure at rest. Sphincter length was reduced both at rest and with maximal squeeze in the rupture group. It is concluded that complete perineal rupture is a condition with possible long‐term consequences such as reduced sphincter strength and partial an

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07806.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractDuring the period April 1984‐February 1985, 4 test samples of totally 380 young Danish women aged 16–20 years old were invited to interview about contraception and sexual behaviour. The response rate was 75,3%.There were 208 (74,0%) who had had sexual debut. Median age was estimated to 16.8 years. At first intercourse 168 (80.8%) used contraception, 36.5% used condom and 36.1% oral contraception (OC). Among teenage‐girls with sexual debut before 15 years old 32.5% were unprotected against pregnancy.At the time of the interview 64.4% did use contraception. The most frequently used contraceptive device was OC (46.6%). Teenage‐girls changed the contraceptive method from condom to OC after sexual debut. A small proportion of sexually active girls (8%) did not use contraception neither at first intercourse nor at the

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07807.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractA Laminaria tent was inserted in the cervical canal of 115 primigravidae prior to vacuum aspiration in the first trimester. A mean dilatation of 9.7 mm was thereby achieved. Only 2 of these patients were treated by antibiotics due to ‘mild’ endometritis, as compared with 10 of 130 control patients due to endometritis and 7 patients due to ‘mild’ endometritis. Three non‐treated control patients had to undergo laparoscopy due to perforation of the uterus during dilatation of the cervical canal. It is concluded that pre‐treatment with the Laminaria tent prior to vacuum aspiration reduces the incidence of per‐ and post‐operativ

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07808.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractAn important task in antenatal care is to identify mothers at risk during pregnancy, with the aim of minimizing morbidity and mortality. This paper describes the outcome of a health questionnaire distributed antenatally to 2086 primigravidae during the Tayside Infant Morbidity and Mortality Study 1980–81. The aim of this study was to test a health questionnaire, known to identify mothers with emotional disturbances, and investigate the outcome of their pregnancies. Two hundred and thirty‐eight mothers (11.4%) had a ‘positive’ score in this study. This rather small group of women had a significantly higher incidence of psycho‐social risk factors. The questionnaire return rate was high, more than 99%, suggesting that such a questionnaire could be used as a screening instrument to identify ‘ri

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07809.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

AbstractTwo groups of insulin‐dependent diabetes mellitus (IDDM) parturients were managed according to different intrapartum protocols and compared with a control group of normal women in labor. Thirty‐seven patients received conventional intensified insulin therapy during pregnancy and intravenous continuous insulin infusion during labor. Twenty‐eight women were managed by continuous subcutaneous insulin infusion pump (CSIIP) throughout gestation and this therapeutic approach was continued during labor. When the two glucose control techniques were compared, CSIIP was superior to achieving and maintaining intrapartum optimal metabolic control, reducing significantly the incidence of acute fetal distress, thus lowering the cesarean section rate and neonatal hypoglycemia. Consequently we concur with the recommendation that firm prepartum as well as intrapartum diabetic control is mandatory for successful management of labor in IDDM pat

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1988.tb07810.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY