摘要:

Abstract.The aim of the present study was to investigate the short‐term complications and consequenses of 216 consecutive female sterilizations. Information was obtained from 211 women (98%) within the first postoperative year. There was one failure (Pomeroy), three skin burns, a vesical lesion and problems with the induction of anesthesia in 2 cases. Thirty‐nine women were bothered by minor complaints for 3 months or more, in most cases by discomfort of the lapa‐rotomy scar. The impact on postoperative marital life was mainly positive. Twenty‐three women expressed doubts whether the sterilization had been sensible, 10 expressed real regret at at least one interview. At one year, 4 stated serious regret. One year after surgery, 68% had told friends about the sterilization; these women were younger than the remainder. Forty‐six percent said they would have preferred an earlier

ISSN:0001-6349    

DOI:10.3109/00016348409156707

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.The long‐term consequences and complications of tubal sterilization were studied. Six years after surgery, information was obtained from 208 of 216 women. Five had been pregnant. Eight had been bothered by their scars for 2 years or more. The majority reported improved conjugal relations and a positive impact on marriage. Eighty‐five percent had told others about the sterilization; the frankness was more common in the younger age groups. Although most women were satisfied, 6% would have preferred the sterilization undone. In 10% of the couples, at least one of the partners held that view. The most common cause for regret was the desire for more children, in most cases with a new spouse. Regret was not correlated to the woman's age, parity or social group. Regret was recorded with significant predominance when the sterilization had been suggested by a doctor at abortion application. In a controlled comparison between Pomeroy laparotomy and laparoscopic electro‐coagulation, no differences in postoperative bleeding patterns were found. The present study indicates that tubal sterilization is not a major cause of subsequent menstrual irregular

ISSN:0001-6349    

DOI:10.3109/00016348409156708

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.Specific estradiol (ER) and progesterone receptors (PR) in the tumor cytosol of 54 patients with primary ovarian cancer were examined. Also 30 benign ovarian neoplasms and 19 normal ovaries were analysed. Of the malignant tumors, 46% contained ER and 41% PR. The ER content of most malignant tumors was 3–30 fmoles/mg protein; three tumors revealed an ER content over 30 fmoles/mg protein. The PR content of most malignant tumors was 8–80 fmoleslmg protein. Three endometrioid adenocarcinomas and three serous cystadenocarcinomas had a PR level over 100 fmoles/mg protein. ER and PR were simultaneously detected in 26% of the malignancies, whereas 39% of them were receptor negative. No significant differences were found between premenopausal and post‐menopausal women, as regards the presence of steroid receptors. Carcinomas were significantly more often ER‐positive than were benign tumors. The ER content of both the benign neoplasms and the normal ovary was low, 5 1 5 fmoles/mg protein, whereas higher PR levels were found in these two groups. The presence of steroid receptors in malignant ovarian tumors can possibly be used as an indicator of hormone dependency of these malig

ISSN:0001-6349    

DOI:10.3109/00016348409156709

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.We report the concentrations of estradiol and progesterone receptors found in the tumor tissue of 5 patients with leiomyosarcoma, 4 of uterine and one of ventricular origin, and of 5 patients with uterine or ovarian carcinosarcoma. Steroid receptor positive and negative tumors were present in both groups of sarcoma. One uterine leiomyosarcoma had a high concentration of estradiol and progesterone receptors, 37 fmoles/mg protein and 156 fmoles/mg protein, respectively. We suggest that steroid receptors should be analysed in all gynecologic sarcomas.

ISSN:0001-6349    

DOI:10.3109/00016348409156710

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.The accuracy of contrast‐enhanced computer tomography (CT) of the pelvis in the detection, characterization and staging of known or suspected pelvic tumors was compared with clinical and operative findings in a prospective study of 79 patients (25 cervical carcinomas, 27 endo‐metrial carcinomas, 10 ovarian carcinomas, 4 vulval or vaginal carcinomas and 13 benign ovarian or uterine tumors). In cervical carcinoma, there was a tendency towards lower staging of the tumor, especially in stage IIa, which is not easily detected in CT. Even small tumors of the cervix and endometrium can be visualized by contrast enhancement, which clearly delineates heavily vascularized myometrium and less enhancing tumor tissue. The accuracy of CT in tumor detection, characterization and evaluation of spread was best in ovarian neoplasms, weakest in cervical carcinomas. The importance of proper CT technique is stres

ISSN:0001-6349    

DOI:10.3109/00016348409156711

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.The present study compared 15 ectopic pregnancies occurring after female sterilization (EPs) with 30 non‐pregnant control patients who had also undergone female sterilization (NPCs) for a history of induced abortion, any pelvic surgery, abdominal surgery, or pelvic infection. EP cases and controls were individually matched for clinic, surgeon, surgical approach, tubal occlusion technique, and date of operation, as well as patients age and parity. The only significant difference was the greater proportion of EP patients, reporting a history of induced abortion (matched triplet odds ratio = 9.0, 95% confidence limits = 1.39, 58.26). Women with EPs were further compared with 78 women with post‐sterilization intra‐uterine pregnancies (unmatched). Results again show a significantly greater risk of conceiving an EP following previous induced abortion (odds ratio 5.8, 95% confidence limits =1.78, 18.60). Women with previous abdominal surgery also ran a significantly higher risk of post‐sterilization EP (odds ratio 10.0 95% confidence limits = 2.45, 40.83). Limitations of the data and clinical implications of the results are di

ISSN:0001-6349    

DOI:10.3109/00016348409156712

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.Premature rabbit neonates, delivered on day 28 of gestation, were treated with a single dose of dibuturylade‐nosine‐3′:5′‐cyclic monophosphate (cyclic AMP), 300 mg/kg, immediately after delivery, saline‐injected litter‐mates serving as controls. All animals were kept in body ple‐thysmographs and ventilated artificially with 100% oxygen for 1 h, with a maximal tidal volume of 10 ml/kg body weight. Lung‐thorax compliance was significantly improved in animals treated with cyclic AMP, both 30 and 60 min after onset of ventilation (0.92±0.09 vs. 0.59±0.08 ml/cm H20.kg and 0.96±0.09 vs. 0.53±0.08, p>0.005), but there was no improvement in alveolar air expansion, evaluated histologically. Phosphatidylglycerol was absent in alveolar wash from all control animals, but present in 3 of the 8 pooled samples from the animals treated with cyclic AMP; this difference was not statistically

ISSN:0001-6349    

DOI:10.3109/00016348409156713

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.In a one‐year population, 1977, of newborn infants admitted to the Neonatal Intensive Care Unit (NICU) the incidence of persistent neurodevelopmental handicaps was 3%, i.e. 13 of 427 survivors at 2 years of age. Transient abnormalities during the first 6 months of life were found in 63 infants, but after 6 months of age they were all normal at follow‐up examinations. Most mothers with infants showing transient abnormalities or persistent handicaps had a high‐risk pregnancy but one‐third (35.5%) had a low‐risk pregnancy and in this group 4 out of 7 cases with persistent major neurodevelopmental handicaps were found. In the total one‐year population, 6% showed ominous fetal heart rate patterns (FHR) in labor compared with 31% of infants with later abnormalities and handicaps. Furthermore, all 13 infants with persistent handicaps had a normal Apgar score at 5 min, indicating that Apgar scoring was less predictive than FHR for neurodevelopmental outcome. Altogether 54 infants born in 1977 were small for gestational age (SGA): 33 NICU‐treated and 21 not NICU‐treated. Seven (6 NICU‐treated, 1 not NICU‐treated) had transient abnormalities (12.9%). No SGA infant developed persistent handicaps. The results suggest an improved obstetric and neonatal ca

ISSN:0001-6349    

DOI:10.3109/00016348409156714

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.Both vasopressin and PGF2alphaare effective uterine stimulants in the non‐pregnant human uterus, especially around the onset of menstruation. In order to clarify the relationship of these hormones to menstrual pain, plasma concentrations of vasopressin and two prostaglandin metabolites (lS‐keto‐B.H‐dihydro‐PGF2alphaand 11‐ketotetranor PGF metabolites) were measured in serial blood samples taken premenstrually and during menstruation. Five women with premenstrual pain gave 7‐9 blood samples at intervals of 30 minutes on the day preceding the onset of menstruation. From 5 women with severe primary dysmenorrhea a corresponding series of blood samples were taken during the first day of menstruation. Two groups of 5 women with no symptoms served as controls, either premenstrually or during menstruation. In the women with premenstrual pain the vasopressin concentrations were significantly higher than in the corresponding control group. Even higher and markedly fluctuating vasopressin levels were found in the women with dysmenorrhea who, in general, had more intense pain than the women with premenstrual symptoms. In the group with dysmenorrhea there was also a significant rise in plasma concentration of the PG metabolites. No such increase was seen in the group with premenstrual pain. It is concluded that the pathophysiology of premenstrual pain could imply increased vasopressin secretion. The more severe pain in primary dysmenorrhea seems to be the result of a combined effect of vasopressin

ISSN:0001-6349    

DOI:10.3109/00016348409156715

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Abstract.Intra‐uterine fetal movements indicate the wellbeing of the fetus and can be used in the detection of chronic fetal asphyxia. The daily variations in fetal activity follow an irregular pattern, though showing a peak of activity in the evening. The pattern of nocturnal activity is not known. In this study, fetal movements were monitored by maternal subjective recordings in 116 women with a normal pregnancy. In gestational weeks 31‐40, fetal movements were recorded intermittently for at least 3 hours, both in the daytime and at night. In the daytime, fetal activity was moderate. A maximum occurred in the evening between 9 and 10 p.m. At night there was a period of minimum activity between 1 and 5 a.m. A minor peak in fetal activity was seen between 7 and 8 a.m. The frequency of fetal movements followed a pattern of a circadian rhythm, which was influenced by exogenous fact

ISSN:0001-6349    

DOI:10.3109/00016348409156716

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY