摘要:

Abstract.Local uterine blood flow was measured by the hydrogen gas clearance method in 36 women before and after injection of oxytocin. In women with secondary amenorrhoea mean myometrial blood flow was 99.0 ± 12.75 ml/min.100 g. No or only a slight reduction of myometrial blood flow was obtained after administration of oxytocin. During the first few days after therapeutic abortion performed in the first trimester of pregnancy, mean myometrial blood flow was 124.3 ± 15.71 ml/min. 100 g. After injection of oxytocin, myometrial blood flow was reduced to a mean of 19.7 ± 6.07% of controls. In the first trimester of pregnancy and during the first few days after therapeutic abortion, cervical uterine blood flow was not or only slightly reduced after administration of oxytoc

ISSN:0001-6349    

DOI:10.3109/00016347409162156

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.Serum and urine samples from 148 healthy female children and adults were studied, ranging from girls with a bone age of 8 years to adulthood. All samples from menstruating girls were obtained between the 7th and 10th days of the menstrual cycle. The blood sample was taken on the same day as the collection of 24‐hour urine sample was completed. The purpose of the study was to investigate the endocrine processes with as many parameters as possible, before and after the menarche. In assessing the results account was taken of the bone age, the gynecological age, and Tanner's puberty classification into 5 groups. Our results show that a girl's sexual and endocrine development had begun before she reached a bone age of 8 years. In the present series the FSH level at the age of 8 equalled a low adult follicular phase level, 1.12 ng/ml, and by the menarche it had increased to 1.84 ng/ml. In the lowest age group of the present series, 8 years, the mean LH level was 0.70 ng/ml, and increased until at the menarche it was 1.19 ng/ml. The initial value for total urinary estrogens at the age of 8 was 4.63 μg/24 h and increased until at the menarche it was 10.20 μg/24 h. From this level the estrogen excretion continued to increase for another 3 years, until at the age of about 16 years it reached an adult level of about 17 μg/24 h. According to this study the menarche seems to be followed by a “steady phase” of some 18–24 months in hormone excretion, with practically all hormone values remaining constant. Hormone excretion in girls around the age of puberty seems to show a slow, almost linear increase, without any remarkable peaks before the menarche, and the endocrine maturation seems to continue up till 5 years after th

ISSN:0001-6349    

DOI:10.3109/00016347409162157

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.Glucose‐6‐phosphate dehydrogenase, isocitrate dehydrogenase, DNA, RNA and total nitrogen were analysed in the rabbit placenta during its hypertrophic response to ovariectomy. Isocitrate dehydrogenase activity was increased in the experimental placentae. Glucose‐6‐phosphate dehydrogenase, DNA, RNA and total nitrogen were un

ISSN:0001-6349    

DOI:10.3109/00016347409162158

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.Representative ovarian biopsies were obtained from 30 pregnant women aged 15 to 40. Group I consisted of 6 women with pregnancies of a gestational age of 9 to 18 weeks, and group II consisted of 24 women with pregnancies of a gestational age of 36 to 42 weeks.The number of primordial follicles varied considerably in both groups, but seemed to be mainly dependent on the age of the individual woman. We did not examine the follicular development before the 9th week of pregnancy, but at least from that time a normal development of follicles up to the stage of Graafian follicles was observed in the great majority of women.A typical decidual reaction in the ovarian cortex was found in all women in group II, but this reaction may also occasionally occur very early in pregnancy. For instance, we observed a marked decidual reaction in one woman in the 9th week of pregnancy. The decidual reaction was always located beneath or adjacent to the surface epithelium, and usually it was of the nodular form, but it might also occur as single cells or as more diffuse and confluent formations of decidual cells. In all cases of typical decidual reaction, the macroscopic appearance of the ovary was characteristic; the ovarian surface presented a gyriform appearance due to a network of thin, pale red ridges and small nodules. An interesting observation in group I was that the decidual reaction in all cases seemed to be preceded by the existence of nodules or more confluent areas characterized by a loose, proliferative connective tissue containing many fibroblasts and capillaries.The most consistent finding in both groups was the proliferation and luteinization of the theca cells surrounding both the growing and atretic follicles. However, it should be emphasized that these luteinized theca cells were only found around antral and Graafian follicles and atretic follicles of similar size, but never around even the largest primary follicles.We are not convinced of the significance of the previously described so‐called surface cell proliferation, even if similar changes were observed in 57% of the 30 women investigated. These changes were mainly observed in areas where the epithelium covered depressed or retracted parts of the ovarian stroma. On the other hand, the prominent decidual nodules were covered by a thin layer of flattened epithelial cells. We therefore believe that the changes in the surface epithelium is merely an unspecific phenomeno

ISSN:0001-6349    

DOI:10.3109/00016347409162159

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.Phospholipid concentrations were measured in 118 samples of amniotic fluid throughout the last trimester. In 112 of these, all six fractions were measured including total phospholipid content. The findings are correlated with gestational age, maternal disease and fetal outcome. Lecithin levels normally start to rise sharply from 34 weeks. Respiratory distress syndrome is shown to be associated with abnormally low concentrations of lecithin and lecithin sphingomyelin ratios below 2.0.

ISSN:0001-6349    

DOI:10.3109/00016347409162160

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.Fibrinolytic inhibitors of plasminogen activation (urokinase inhibitors) and of plasmin (alpha2‐macroglobulin, antiplasmin and total antitrypsin activity) were measured in retroplacental blood and compared with that in placental extract and maternal venous blood obtained at 40 deliveries. In placental extract the concentration of inhibitors of plasminogen activation was extremely high. In contrast, it was found to be normal in retroplacental blood and close to the value found for maternal venous blood. It therefore seems unlikely that inhibitors from the placenta enter the bloodstream and contribute to the reduction of the fibrinolytic activity in the maternal circulation during pregnanc

ISSN:0001-6349    

DOI:10.3109/00016347409162161

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.99 pregnant women, 5 to 11 weeks, were examined by a combined ultrasonic B‐scan and Doppler method to detect fetal heart activity. The fetus was localized accurately by B‐scanning and the heart activity was detected through the mother's abdominal wall with 100% certainty at eight weeks of pregnancy (menstrual age). The earliest fetal heart activity detected was in a pregnancy which dated 44 days from the last menstrual period. Positive findings were recorded on tape and photographed from the oscilloscope scr

ISSN:0001-6349    

DOI:10.3109/00016347409162162

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.Placental scintigraphy with113mIn (Indium) combined with cervical marking with a shielded57Co (Cobalt) radioactive source is easy to perform and causes no harm to the patient. The radiation dose to mother (gonads, about 15 mrad) and fetus (about 10 mrad) is extremely low. A total of 111 patients have been examined. The method provides accurate results in localizing the placenta. Low implantation or placenta praevia were diagnosed in 45 patients. Scintigraphic evaluation of disturbances in placental blood flow has given promising results (16 patients). In a great number of cases it has been possible to avoid unnecessary and expensive hospitalization by excluding placenta praevia as cause of vaginal bleeding. It is a reliable method for localizing the placenta before diagnostic amniocentesis.

ISSN:0001-6349    

DOI:10.3109/00016347409162163

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.In a series of 477 women of child‐bearing age, altogether 1270 blood samples were tested for hemoglobin, hematocrit and mean corpuscular hemoglobin concentration (Hb, Hct and MCHC) and the results plotted against a normal menstrual cycle. There was a pronounced tendency towards an increase of Hb together with Hct from the early menstrual phase until the post‐ovulatory period, with a subsequent decrease towards the end of the cycle. No cyclical pattern of MCHC was observed. These variations in hematological parameters are in good agreement with present knowledge of the hormonal changes during the menstrual cy

ISSN:0001-6349    

DOI:10.3109/00016347409162164

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Abstract.An operation is described for women with a wide external urethral meatus, suffering from recurrent urethritis following intercourse. It consists of the formation of a structure similar to the frenulum of the prepuce in the male. On pulling this band the external urethral orifice will close. This will happen at penetration by the penis.

ISSN:0001-6349    

DOI:10.3109/00016347409162165

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY