摘要:

Abstract.Phosphatidylinositol (PI) and phosphatidylglycerol (PG) appear normally in the amniotic fluid during the last weeks of pregnancy. The present study indicated as have previous studies (5, 6, 8, 10) that these phospholipids are linked to the surfactant system in the fetal lung.The concentrations of lecithin (L), PI, PG and sphingomyelin (S) were measured in 207 samples from 165 normal pregnancies. The augmentation in PI was found to parallel that in lecithin, and the PI/S ratios reached maximum values at about 36 weeks of gestation. The augmentation in PG appeared about two weeks later.Eleven premature infants who contracted respiratory distress syndrome (RDS) had significantly lower PG concentrations than 15 premature infants with no RDS (p<0.01). No correlation to the PI concentrations could be observed. All but one of the 11 affected infants had low L/S ratios.

ISSN:0001-6349    

DOI:10.3109/00016347909154038

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Beta‐HCG in serum was analysed in 64 cases of ectopic tubal pregnancy who were operated upon during 1974–1976. The case material was divided into three different groups; ruptured ectopic pregnancy, ectopic pregnancy accompanied by amenorrhea or adnexal mass and ectopic pregnancy without palpable adnexal mass and amenorrhea. The mean HCG levels for the three groups were 8 790IU/1, 2 580 IU/1 and 690 IU/1, respectively, which related more to the symptoms than to the estimated length of pregnancy. Eleven per cent of the women had an IUD and five per cent were taking low dose gestagens. Screening of cases with acute lower abdominal pain or irregular vaginal bleeding with beta‐HCG in serum will facilitate an early diagnosis of ectopic pregnancy and be of special value in patients with less typical sym

ISSN:0001-6349    

DOI:10.3109/00016347909154039

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.The effect of a single dose of betamethasone on the maternal plasma concentration of estriol and Cortisol was studied. The concentration of estriol decreased rapidly. A maximal suppression of about 70 per cent was seen after 6‐24 hours. A similar influence on the maternal plasma concentration of Cortisol was observed. HCS (human chorionic somatomammotropin) was not influenced by betamethasone. These facts have to be taken into consideration after treatment with synthetic corticosteroids in high risk pregnancie

ISSN:0001-6349    

DOI:10.3109/00016347909154040

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.A method for detecting meconium in the amniotic fluid is described. Samples of maternal serum, cord serum and amniotic fluid were tested for alkaline phosphatase and transaminases activity in 32 healthy, term gravidas during labor in whom meconium stained amniotic fluid was found. The values obtained were compared to those of a control group consisting of 32 normal term pregnancies in whom the amniotic fluid was clear.Mean alkaline phosphatase activity was significantly higher in the study group in all three compartments ‐ maternal, fetal and amniotic fluid.A significant and positive correlation between levels of alkaline phosphatase in the amniotic fluid and in maternal serum was found in the study group. Alkaline phosphatase value of 550 IU/L or more in maternal serum was diagnostic and levels between 350–500 IU/L were highly suggestive for the presence of menconium in the amniotic fluid.Mean levels of transaminases (SGOT and SGPT) were similar in the two groups and all were within normal range. The origin of alkaline phosphatase and the mode of transfer of the three enzymes are also discussed.It is suggested that this method can also be used during the third trimester of pregna

ISSN:0001-6349    

DOI:10.3109/00016347909154041

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Serum prolactin and thyroid stimulating hormone (TSH) levels were measured following administration of thyreotropin releasing hormone (THR) in 17 preeclamptic patients and 18 normal pregnant controls.31st to the 35th pregnancy week the preeclamptic patients showed increased basal serum prolactin and TSH levels compared to controls, but later in pregnancy the differences disappeared. Following TRH stimulation, the serum prolactin and TSH responses were similar in women with and without preeclampsia. A possible role of prolactin in the development of preeclampsia is discussed.

ISSN:0001-6349    

DOI:10.3109/00016347909154042

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Intervillous blood flow was measured by a new intravenous133Xe method before and during induction of general anesthesia for cesarean section in 10 healthy mothers. The flow values showed a highly significant decrease (p<0.001) (35 per cent on an average) at the time of anesthesia compared with the control values. The impairment was observed in all the cases. The role of the maternal changes in hemodynamic parameters and acid‐base balance as a background of this decrease is discusse

ISSN:0001-6349    

DOI:10.3109/00016347909154043

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.The published results of cervical cerclage are almost invariably good and there is little mention of complications. Forty per cent of 52 pregnancies, with 38 early “prophylactic” and 14 late “therapeutic” operations, ended after 260 days' gestation. In 73 per cent a viable infant was born.The most frequent complication was premature rupture of the membranes (12 cases), followed by slipping suture (7) and premature delivery (6). Intra‐uterine infection was fairly common. The implications and possible causes of this high rate of complications are

ISSN:0001-6349    

DOI:10.3109/00016347909154044

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.The literature on the course of pregnancies following conization of the uterine cervix has been studied. It is demonstrated that an evaluation of the possible effect of conization upon subsequent pregnancy should be based upon a comparison of either pregnancies before and after conization or upon a comparison between pregnancies in women with a previous conization and in a control group of women without conization. In both cases the possible influence of conization can be evaluated only if the patient material is described as regards age, parity, number of previous pregnancies, smoking habits, etc., factors which may all influence the course of pregnancy. None of the previous publications have described the patient material sufficiently, and most studies have not tried to set up control groups.Due to these deficiencies we do not find it justified that conization leads to reduced fertility, increased frequency of spontaneous abortion, nor to increased perinatal mortality. An increased prematurity rate may not be rejected, however, but this point has not been adequately evaluated in the previous papers.

ISSN:0001-6349    

DOI:10.3109/00016347909154045

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.A study of the supplementary value of an endocervical swab smear in addition to cervical scraping in the cytological diagnosis of cervical neoplasias is presented. The two sampling techniques were applied to a population with a high prevalence of neoplastic cervical disease. The endo‐cervical swab smear was a useful adjunct in the detection of mild and moderate dysplasia, and a combination of the two sampling methods decreased the false negative rate in the diagnosis of intraepithelial, as well as invasive neoplasia. In the sphere of specific cytological diagnosis cervical scraping was found to be the more accurate method for diagnosing severe dysplasia and carcinoma in situ, while endocervical swab smears were more useful in diagnosing mild and moderate dysplasia. Differences between the results obtained in our study and comparable studies are discussed. It is concluded that the endocervical swab smear is a valuable adjunct to cervical scraping in the diagnosis of malignant cervical disease. It should not, however, be used as the only sampling method as it produces a higher proportion of unsatisfactory smears, and also because the severity of the epithelial lesion is more likely to be underestimate

ISSN:0001-6349    

DOI:10.3109/00016347909154046

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.At the Finseninstituttet and the Radium Centre in Copenhagen, from 1971‐1975 inclusive, cryosurgery was carried out altogether 59 times on 57 patients. Only 8 patients showed histopathological changes in the biopsies sufficient to indicate conization.Hysterectomy was carried out on 8 patients. In 7 of these the removed uteri showed either no malignant changes or changes of a lesser degree of malignancy than those, which had indicated cryotherapy. Invasive growth was discovered only in 1 patient, who later underwent a total hysterectomy by the Wertheim method. A biopsy on 1 patient with carcinoma in situ, suspected invasive growth, was treated with radiu

ISSN:0001-6349    

DOI:10.3109/00016347909154047

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY