ISSN:0001-6349    

DOI:10.3109/00016349209007962

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0001-6349    

DOI:10.3109/00016349209007963

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

The detectability of human papillomavirus DNA from cervical smears was studied by DNA tests of varying sensitivity. The results were correlated with cervical cytologic abnormalities. A total of 326 women examined at the gynecological outpatient clinics of five Scandinavian hospitals were enrolled in the study on the basis of previous pathological cervical smear or clinically suspected human papillomavirus (HPV) infection. The cervical smears were examined for HPV‐DNA of types 6/11, 16 or 18 by two direct DNA tests, the AffiProbe HPV test and the ViraType test. The proportion of HPV‐DNA‐positive women with normal cytology, benign atypia (mild nuclear and cytoplasmic changes without signs of dysplasia) and dyskaryosis were 16% (12/77), 27% (42/156) and 37% (30/81), respectively. The smears negative for HPV types 6/11, 16 or 18 and those yielding discrepant results in the two commercial tests were also analysed by the polymerase chain reaction (PCR) method. By PCR analysis, the HPV 6/11, 16 or 18 DNA positivity increased from 27% to 41%. The increase was particularly pronounced among the women with dyskaryosis in cyt

ISSN:0001-6349    

DOI:10.3109/00016349209007964

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Very low birthweight liveborn infants (<1,500 g, VLBW) born in Sweden 1973–88 were identified from the Medical Birth Registry and efforts were made to remove wrongly recorded birthweights −9% of infants with a registered birth weight below 1,500 g were removed. Some VLBW infants were not recorded in the register and the estimate of the prevalence at birth of VLBW infants is therefore slightly underestimated. It increased from about 5.5 per 1,000 during the period 1973–84 to 6.7 per 1,000 during 1987–88. 18% of VLBW infants were involved in multiple births. Median Apgar score at 5 min increased for each 100 g birthweight class. Even at a birthweight between 1,400 and 1,499 g. a low Apgar score at 5 min was seen in 20%. The rate of cesarean section increased between 1973 and 1983 from about 10% to 60%. One‐year survival for infants with a birthweight<1,000g increased from less than 20% in 1973–75 to 50% in the 1986–88 cohorts. Corresponding figures for infants with a birthweight between 1,000 and 1,499 g were 60% and 90%. A markedly better one‐year survival is already evident in the 600–699 g class. On stratifying for 100 g birthweight class, perinatal death risk was higher in hoys than in girls and higher in multiple births than in singletons. An increased rate of congenital malformations was seen in the 1,000–1,499 g class but not i

ISSN:0001-6349    

DOI:10.3109/00016349209007965

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

The significance of antiphospholipid antibodies in pre‐eclamptic women has not been thoroughly elucidated. The purpose of this study was to determine the proportion of pre‐eclamptic women who were antiphospholipid antibody positive, and to elucidate the significance of these antibodies regarding growth retardation and neonatal outcome. Positive levels of anticephalin antibodies, which are antiphospholipid antibodies, were detected in 7 (19%) out of 37 pre‐eclamptic women, as compared with none of 40 in a control group of normotensive women at similar stage of pregnancy (p= 0.004). The birthweight percentiles of the neonates of anticephalin antibody positive women were significantly lower than those of the neonates of anticephalin antibody negative women (p= 0.018). Four of 7 infants of anticephalin antibody positive women were growth retarded (<2.5th percentile). This was a significantly larger proportion than that for anticephalin antibody negative women (3/30) (p =0.004). The 95% confidence interval for the difference between the two proportions was 0.10 to 0.85. Two of the 7 neonates of anticephalin antibody positive women died during the neonatal period, compared with none of the 30 neonates of anticephalin antibody negative women (p =0.003). Thus, our study suggests that positive levels of anticephalin antibodies in pre‐eclamptic women increase the risk for growth retardation and neonata

ISSN:0001-6349    

DOI:10.3109/00016349209007966

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

A case report is presented of a woman who was “Tasered”® by law enforcement personnel while 12 weeks pregnant. The Taser® (Thomas A. Swift's Electric Rifle) is an electronic immobilization and defense weapon that has been commercially available since 1974. The Taser® was developed as an alternative to the 38 special handgun. The patient was hit with Taser® probes in the abdomen and the leg. She began to spontaneously miscarry 7 days later and received a dilatation and curettage procedure 14 days later for incomplete abortion. The world's literature on electrical and lightning injury to pregnant women is reviewed, and the mechanism of action of Taser® injury is discussed. As use of the Taser® becomes more common, obstetrical clinicians may encounter complications from the Taser®

ISSN:0001-6349    

DOI:10.3109/00016349209007967

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Transabdominal amnio‐infusion preceding labor induction was evaluated as a means of avoiding fetal distress and cesarean delivery in patients with oligohydramnios. A preliminary study was performed in 8 consecutive term or post‐term pregnancies complicated by severe oligohydramnios (ammotic fluid index ≤ 1 cm) with unripe cervices (Bishop's score ≤ 3). Warm saline was injected through a spinal needle under ultrasound control. Vaginal delivery occurred in 7 cases; cesarean section was performed in one patient for failure to progress. There was no meconium aspiration and no sign of fetal d

ISSN:0001-6349    

DOI:10.3109/00016349209007968

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Eighteen patients, under the age of 60 years, who have been treated with local excision of the vulva, participated in the study in which sexual function and somatopsychic reactions were evaluated by personal interviews. Furthermore both objective and subjective cosmetic results were registered. After this type of operation, fewer than one‐third of the patients had postoperative sexual and somatopsychic problems, whereas more than half of the patients undergoing vulvectomy did report such problems. Fourteen out of 18 patients were satisfied with the cosmetic result and in 12 of the patients no disfiguration was found. This study shows that local excision of intra‐epithelial neoplasia of the vulva is far less sexually traumatic than is vulvect

ISSN:0001-6349    

DOI:10.3109/00016349209007969

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

The clinical efficacy and safety of clindamycin‐gentamicin versus doxycycline‐cefoxitin in the treatment of acute pelvic inflammatory disease was evaluated in a comparative, randomized, prospective, multicenter study. Ten investigators enrolled 170 patients. Those judged to be eligible for efficacy were 60/88 (68%) who received the clindamycin‐gentamicin regimen and 55/82 (67%) of those treated with cefoxitin‐doxycycline. A successful clinical outcome was attained for 52/60 (87%) and 46/55 (84%) for patients treated with clindamycin‐gentamicin and cefoxitin‐doxycycline, respectively, a difference that was not statistically significant. In the clindamycin‐gentamicin series, 8/8 (100%) of patients with positiveC. trachomatisculture at baseline were culture negative at the late follow‐up 21–35 days after treatment. For those given cefoxitin‐doxycycline, 9/11 (82%) who hadC. trachomatisat pretreatment showed eradication at follow‐up.Neisseria gonorrhoeaewas present at baseline in 8/60 (13%) of the clindamycin‐gentamicin patients and in 9/55 (16%) of those treated with cefoxitin‐doxycycline. Of those who had appropriate follow‐up cultures performed, 6 in the clindamycin‐gentamicin group and 8 in the cefoxitin‐doxycycline series, all showed eradication of the organism. It is concluded that clindamycin‐gentamicin and cefoxitin‐doxycycline have similar clinical cure rates for acute pelvic inflammatory disease, and based on this limited experience, it is suggested that the clindamycin‐gentamicin combination will satisfactorily eradicateChlamydia trachomatisandNeisseria gonorrhoeaewhen either o

ISSN:0001-6349    

DOI:10.3109/00016349209007970

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Pretreatment assessment of blood lymphoid cells was performed in 44 patients with carcinoma of the cervix and in 19 healthy controls. White blood cells were determined by routine differential counting, and T‐lymphocyte subsets and monocytes were quantitated using monoclonal antibodies. Increase in monocyte numbers, as determined by the 1D5 antibody, was seen in the cancer patients, especially in the group with advanced disease. No change in T‐lymphocyte subpopulations could be found. During the 5‐year follow‐up period, 17 patients had a recurrence or died of cancer. The best prognostic information was obtained from conventional clinical parameters, e.g. stage, tumor size and lymph node status. Increased numbers of granulocytes and monocytes were found in advanced stage disease but had no independent prognostic influence. In pelvic lymph node biopsies taken from patients undergoing Wertheim‐Meigs operation the T‐helper/T‐suppressor ratio was higher and the monocyte number lower than in peripheral blood. No correlation could be detected between node cell distribution and the prognosis. It is concluded that immunological testing, as performed in this study, elicits very little new prognosti

ISSN:0001-6349    

DOI:10.3109/00016349209007971

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY