摘要:

Blood viscosity was measured in 14 healthy, menstruating women, aged 17‐51 years and in 10 healthy, postmenopausal women, aged 55‐64 years. The fertile women were studied once a week during a normal menstrual cycle and the postmenopausal women twice with an interval of 2 weeks. Blood viscosity was measured at natural hematocrit as well as at hematocrit 45%. In the postmenopausal women no changes in blood viscosity were found. In the fertile women, blood viscosity at hematocrit 45% was lowest at the start of the menstrual bleeding and increased to a peak at day 7 (p<0.01), with a similar pattern when measured at natural hematocrit. Plasma viscosity also had its lowest value at the onset of menstrual bleeding, increasing to a maximum at day 21. Changes in plasma triglycerides, but not in fibrinogen or cholesterol, seemed to contribute to this increase. Plasma factors only partly explained the variations in blood viscosity, and changes in red cell properties were also found to be of importance. The clinical significance of these rheological changes remains to be established, but at least theoretically there may be an increased risk for thromboembolism, e.g. at surgery, during days 5‐15 of the cycle. In studies on blood flow and rheological conditions in fertile women, it seems advisable to standardize for time in the menstrual

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07823.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Small porcelain pellets were inserted into one of the uterine horns of virgin guinea pigs. Mating caused pregnancies only in contralateral, non‐pellet‐containing uterine horns. The number and morphology of uterine nerve structures was studied immunohistochemically. In pellet‐surrounding tissues of virgin animals the number of nerves was reduced and remaining nerve structures displayed signs of degeneration. This nerve reduction was further advanced in early to mid‐pregnancy when almost no nerve structures could be detected. Myometrial strips were transplanted to the anterior eye chamber and became reinnervated by adrenergic nerves. The pattern and structure of the adrenergic reinnervation did not differ between strips taken from virgin animals, untreated or following chemical sympathectomy, or taken from primiparous animals following pregnancy induced sympathectomy. The adrenergic reinnervation of transplants from virgin animals was not affected by pregnancy of the recipient animal. It is suggested that the uterine innervation can be influenced by local, mechanically‐induced effects, which during pregnancy co‐operate with conceptus‐related humoral factors to cause an almost total uterine nerve degeneration. The ability of uterine adrenergic reinnervation is probably not significantly influenced by local environmental tissue factor(s), but is related rather to extent of

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07824.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

To examine the fluctuation in plasma β‐Endorphin (β‐EP) concentration throughout the menstrual cycle, 8 healthy females with normal cycles were studied. After an overnight fast, the subject's blood samples were drawn between 8 and 10 a.m. They gave blood at 2 or 4 day intervals through three menstrual cycles. Using the LH surge as day 0, the mean β‐EP concentrations were higher on days −10, −9, −8 (6.5±2.6, 6.9±3.8 and 6.7±2.7 pmol/l, follicular phase), on days −1, 0, +1 (9.2±3.3, 9.1 ±5.2 and 8.8±3.3 pmol/l, periovulatory phase), and on days +9 and + 12 (8.6±2.5 and 8.8±3.8 pmol/l, luteal phase). Most β‐EP levels were low during menstruation. The rise and fall in β‐EP and its relation to temporal LH and FSH secretion are discussed. The findings show that three β‐EP rises take place during the menstrual cycle and that β‐EP may be inv

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07825.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

In the authors' Department, 144 cases of placenta praevia were treated in the course of 15 years. This number amounted to 0.54% of all births. The sex ratio of fetuses inassociated with this complication was 166.6, which exceeds that of all neonates during the same period of time. A preponderance of male babies was noted when the material was further analysed according to maternal age, parity and neonatal birth weight.

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07826.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

An epidemiological statistical model was designed to identify women at low and high risk of developing endometrial cancer (EC). The model was based on a number of easily identified clinical factors such as hirsutism, parity, diabetes mellitus, body mass index (BMI) and smoking. A retrospectively collected series of 77 women aged 31 to 45 years with EC and a prospectively collected series of 122 women aged 43 to 70 years with EC were compared with 1409 controls. The participation frequencies in the two case materials were 83 and 87%, respectively. The series were examined by means of a questionnaire. In a stepwise multiple logistic regression analysis of the entire series the following variables were found to be significant; hirsutism, parity, BMI, diabetes mellitus and smoking.

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07827.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

During the last decade, 154 patients treated with human menopausal gonadotropin humanchorionic gonadotropin developed hyperstimulation necessitating hospitalization in 201 cycles. Moderate ovarian hyperstimulation occurred in 116 of the patients and severe ovarian hyperstimulation in 34. Sixteen patients underwent operative procedures. Twelve patients underwent puncture of the pleura or abdomen to drain symptomic hydrothorax or ascites, with clinical improvement of the symptoms in all of them. Three patients had coagulation abnormalities, and 1 patient had thromboembolic phenomena. Hyperstimulation seems to be associated with an increased pregnancy rate, since seventy‐five pregnancies (35%) occurred in the study group. Appropriate monitoring can reduce the rate of OHSS but it should be kept in mind that death due to OHSS may occu

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07828.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

The purpose of this study was to establish the frequency of complications following legal abortion at our hospital, and also to examine the use of contraceptives among these patients. All women who requested abortion in the first or second trimester up to week 15 during an 8‐month period (n =1000) were included in the study. The patients were characterized with regard to age, parity, previous abortion, contraceptive technique before and after the abortion, presence of endocervical/urethralChlamydia trachomatisand frequency and type of somatic complications following the abortion. The overall frequency of complications (infection, bleeding, recurettage) was 5.4%, and 2.7% were readmitted to the hospital. No certain relation between complication rate and gestational length, age or parity was seen, possibly related to selective prostaglandin pretreatment of the cervix and doxycycline treatment of patients with positive cultures forChlamydia trachomatis.In contrast to previous Scandinavian studies, we found a smaller proportion of young patients, a low percentage of Chlamydial infections, and an unchanged high rate of failure to use contraceptive

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07829.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Controversy still dominates the discussion of the correct method for delivering patients with a previous cesarean section (C/S) scar. Although many have abandoned the slogan of “once a cesarean, always a cesarean”, repeat cesareans are still the rule in many institutions. We have abandoned this dogma, and are now advancing to new ideas and are promoting a new protocol. Nineteen post‐one cesarean section patients were induced on various indications by means of PGE2pessaries. Close surveillance revealed no complications and 16 were delivered vaginally. All neonates had good Apgar scores, and all scars were found to be intact upon examination. We recommend cautious use of prostaglandins for selected post‐cesarean p

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07830.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Carcinoma of the cervix is known to have a multifactorial etiology and several factors are implicated in increasing the risk of eventual development of cervical malignancy in a woman. This communication attemps to highlight the small family norms in the prevention of uterine cervical cancer. Data on 117,411 cytologically screened women were considered in which 215 women were found to have cervical cancer. Age adjusted rates of malignancy per 100,000 women in three parity groups (0‐2, 3‐4 and 5+) were 91.1, 174.4 and 393.1 respectively. An increasing trend of malignancy was noticed with increasing parity in women who had their consummation of marriage before 18 years as well as after 18 years. It may be concluded that the small family norm (only two children) being advocated as a part of a national family welfare program would be another primary prevention measure against uterine cervical can

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07831.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

In view of the role of the calcium ion in the inflammatory process, the effect of Diltiazem — a calcium antagonist—on the formation of intraperitoneal adhesions was studied in rats after induced trauma to the uterine serosa. It was found that intraperitoneal application of diltiazem inhibited adhesion formation to some extent, whereas intramuscularly administered Diltiazem did not. A dual effect of calcium antagonists on the formation of adhesions is sugges

ISSN:0001-6349    

DOI:10.1111/j.1600-0412.1989.tb07832.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY