摘要:

Abstract.The feasibility of preoperative anticoagulant treatment in connection with gynaecological surgery was studied in a series of 59 patients who were considered to have a predisposition to thromboembolic complications. The anticoagulant drug used was warfarin sodium (Marevan®) and Owren's Thrombotest (TT) method was employed in the control of the treatment. Clinically detectable venous thrombosis or pulmonary embolism did not occur in the series. In 1 case a non‐fatal myocardial infarction was diagnosed postoperatively. There were no deaths in the series. Clinically significant haemorrhagic complications occurred in 5 cases, but could be controlled in all instances. Our experience indicates that preoperative anticoagulant treatment is feasible in connection with gynaecological surgery. If the anticoagulant treatment is supervised carefully, it does not cause any undue increase in the risk of bleeding complications. However, careful haemostasis during surgery is imperative in patients receiving preoperative anticoagulant treatment. A TT level of 10–20% seems to be suitable in preoperative anticoagulant treat

ISSN:0001-6349    

DOI:10.3109/00016347009157239

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A case of normal single pregnancy combined with bilateral multiple lutein cysts in the ovaries is reported. Similar cases in the literature are reviewed.

ISSN:0001-6349    

DOI:10.3109/00016347009157240

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.The relationship between maternal health and intrauterine growth of the foetus was studied. A prospective method of study was used and the series included 11 417 pregnant women. All infants of low birth weight and a subgroup of growth retarded infants were compared with a control group of normal weight infants. It became evident that the characteristics and complications of pregnancies resulting in infants of low birth weight differed from those of a control series. It was also apparent that pregnancies resulting in growth retarded infants differed from controls in other respects than those resulting in premature infants as a whole. In studying the causes of prematurity and in the clinical handling of the premature infants it is of utmost importance to be aware of the different categories of infants of low birth weight.

ISSN:0001-6349    

DOI:10.3109/00016347009157241

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A random sample of 503 women from all parts of Norway who had given birth to a child during the last 24 months, were interviewed by the Scan‐Gallup institution. Only 31% of the women thought they had received any kind of analgesia during stage I and 55% when sutured. Nevertheless 80% were satisfied with the treatment and care given, and of the dissatisfied, 70% complained of lack of attention and only 17% of too little analgesia give

ISSN:0001-6349    

DOI:10.3109/00016347009157242

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.Sex‐chromatin and chromosomal investigations were carried out on 98 men, who were examined because of infertility. They all had severely impaired or totally absent fertility as evaluated by seminal analyses. Six were sex‐chromatin positive and had a 47, XXY chromosome complement. Furthermore one had a 47, XYY complement. This patient as well as the other 91 were chromatin‐negative. In another selection of hypogonadal men, both sex‐chromatin positive and sex‐chromatin negative patients with abnormal chromosome complements were found. It is therefore concluded that chromosomal abnormalities are important aetiological factors in male infertility. Chromosome analysis as well as sex‐chromatin analysis is thus necessary in the investigation of male

ISSN:0001-6349    

DOI:10.3109/00016347009157243

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A fibrinolytic inhibitor AMCA (transp‐aminomethyl cyclohexane carboxylic acid) was given i.v. in a dose of 0.01 g/kg bodyweight to 12 mothers about to be delivered by Caesarean section. Immediately after delivery the concentration of AMCA was determined in the maternal blood and in cord blood. AMCA was determined by a chemical method based on high voltage paper electrophoresis and photometric determination of the ninhydrin complex. It was found that AMCA passes through the placenta and that the concentration of the drug in the cord blood can be fairly high (4–31 μg per ml). The possible value of prophylaxis of the foetus with AMCA by the maternal route to check fibrinolytic bleedings (pulmonary or intracranial) sustained during premature delivery is discu

ISSN:0001-6349    

DOI:10.3109/00016347009157244

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A series consisting of 145 post‐menopausal women with uterine bleeding and a control group of 55 post‐menopausal women without this symptom were investigated. The urinary excretion of oestrone, oestradiol and oestriol was measured on three consecutive days. The oestrogenic effect in vaginal smears was determined and the endometrium was histologically investigated. In those patients with uterine bleeding who showed an oestrogenic effect in the endometrium or an endometrial polyp, the urinary excretion of oestrone, oestradiol and oestriol and the oestrogenic effect in the vaginal smear were clearly higher than in the control group, although overlapping occurred. In those patients in the bleeding group who had atrophic or slightly proliferative endometrium or endometrial carcinoma, the urinary oestrogen excretion was low and the oestrogenic effect in the vaginal smear was poorly developed, and did not differ from the corresponding values in the control group. Of the various urinary oestrogen values (oestrone, oestradiol, oestriol and the sum of these) the total value was found to correlate most obviously with an endometrial oestrogenic effect. A positive correlation was also observed between an oestrogenic effect in the vaginal smear and an endometrial oestrogenic eff

ISSN:0001-6349    

DOI:10.3109/00016347009157245

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.Three oral contraceptives with different oestrogen‐progestogen combinations were given to 22 women of fertile age. The possible diabetogenic effect was studied after intravenous glucose tolerance test before the treatment was started and after 1, 6 and 12 months of cyclical therapy. All of the women had a normal menstrual cycle before treatment began. They showed none of the features which suggest prediabetes. Thek‐ and theT½ values were calculated. The intra‐individual variation ofkbetween two tolerance tests was calculated on the basis of figures available in the literature. When thek‐value did not rise linearly, attempts were made to calculate the variation within differentk‐value ranges. The possible diabetogenic effect of the three different drugs was studied in the light of these calculations. In the cases tested, Drug no. 1, which contained nor‐ethisterone acetate (4 mg) – ethinyloestradiol (0.05 mg) (Anovlar), and Drug no. 2, which contained megestrol acetate (4 mg) – ethinyloestradiol (0.05 mg) (Volidan) did not seem to have any diabetogenic effect. On the other hand, Drug no. 3, which contained ethynodiol acetate (1 mg) – mestranol (0.1 mg) (Ovulen), appears to have had a transient diabetogenic effect. It was slightly evident after one month of treatment, statistically significant after 6 months and practically negligible after 1 year of treatment. Further experiments with specific hormones are indicated. Women in the danger zone, i.e. women who have latent diabetes or are in a prediabetic stage should be included in th

ISSN:0001-6349    

DOI:10.3109/00016347009157246

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.The wound complications occurring after a total of over 32 000 gynaecological operations from 1955 to 1967 have been analysed. The average rate of infection was 2.9%. Staphylococcus aureus was found in 29% of cases and in 24% of swabs E. coli was observed. Altogether Gram‐negative bacilli were found in 27% of the infected wounds. Clear differences can be noticed in the numbers of complications following different operations, the fewest complications occurring after abortion made by hysterotomy and operations for malignant disease, and the greatest number after total hysterectomies and operations for incontinence. Prophylactic appendicectomies increased the rate of wound infections to 4.3

ISSN:0001-6349    

DOI:10.3109/00016347009157247

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.The incidence of clear cell type adenocarcinoma in the different parts of the genital canal, the age distribution of the patients, the clinical and histological picture and the theories advanced in the literature as to its histogenesis are reviewed. Four cases diagnosed in 1953–1968 at the Central Hospital of North Carelia are described. One of the tumours occurred in the vagina, two in the cervical canal and one in the ovary. The histopathological diagnosis may be difficult if a pronounced secondary infection is associated with the tumour tissue and the tumour cells are well differentiated. Clear cell adenocarcinoma and Schiller's mesonephroma are obviously two different histological manifestations of the same tumour, and they may also occur combined in the same tumour. That the site of origin is in the remnants of the mesonephric duct must be regarded as still unprove

ISSN:0001-6349    

DOI:10.3109/00016347009157248

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY