摘要:

Abstract.The intraarterial blood pressure was measured at rest and during reactive hyperaemia of the lower legs in seven primigravidae during the first trimester and in six subjects 2 weeks after early legal abortion. Blood pressure measurements were taken in the right brachial artery and in both femoral arteries. Under conditions of rest the mean blood pressure in the femoral artery in relation to the mean pressure in the brachial artery was lower during early pregnancy than 2 weeks after abortion. The peripheral vascular resistance per 100 ml tissue was calculated on the basis of earlier blood flow investigations and the mean arterial blood pressures reported here. At rest it was found to be higher in the arm than in the leg. During reactive hyperaemia in the lower legs the peripheral vascular resistance was found to be almost the same during early pregnancy and 2 weeks after early abortion.

ISSN:0001-6349    

DOI:10.3109/00016347309157082

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Linear penetration, number of penetrating spermatozoa and their motility were studied in 400 semen samples using a capillary tube method and with cervical mucus as a test medium. A close correlation was found between these parameters. All three showed a high correlation with a proposed “penetration score”. Of the semen properties routinely tested sperm motility showed the highest correlation with the penetration paramet

ISSN:0001-6349    

DOI:10.3109/00016347309157083

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Forty‐one patients with ovarian cancer were investigated for the effect of cyclophosphamide stoss therapy on liver function. The patients were tested for serum bilirubin, alkaline phosphatase, aminotransferases (GOT, GPT) serum total proteins, and ten of them also underwent an intravenous galactose tolerance test. Serum total protein was found to decrease significantly during the cyclophosphamide stoss therapy. It was further noted that the number of pathological results for serum total bilirubin, alkaline phosphatase, GOT, and GPT increased during the treatment, whereas the number of pathological half‐lives of galactose tolerance decreased. Fifteen patients underwent 19 intramuscular Homactid tests before the beginning of cyclophosphamide stoss therapy and one and two weeks after the therapy. The responsiveness of the adrenal cortex two weeks after the therapy was found to be lower and shorter in duration, compared with the results obtained before the therapy. Cyclophosphamide stoss therapy was not found to cause any serious disorders of hepatic or adrenocortical funct

ISSN:0001-6349    

DOI:10.3109/00016347309157084

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.241 pregnant women were treated with buccal oxytocin tablets (129) and buccal desaminooxytocin tablets (112) respectively with a view to the induction of labour (135) and the stimulation of labour (106). Delivery was achieved within 48 hours after 190 of the treatments (79%). It was found that the dilatation time was significantly shorter, and the dosage of biologically active compound required was less, for women treated with desaminooxytocin. Otherwise there was no significant difference between the results of treatment, and the frequency of side‐effects and complications was deemed to be of the same magnitude in the two treatment group

ISSN:0001-6349    

DOI:10.3109/00016347309157085

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.The effect of oxygen and xantinol nicotinate (Complamin®) alone or in conjunction on uterine perfusion and the acid‐base balance and po2of the fetal blood was studied in gravidae suffering from various diseases. The series consisted of 40 gravidae with hypertension and 32 suffering from other diseases. Oxygen ventilation had an unfavourable effect on uterine perfusion in the latter group, just as was found in normal gravidae in a previous study. A still greater depression of uterine perfusion was observed in the hypertensive patients. The fetal po2rose slightly and the fetal pH fell during oxygen ventilation. Fetal BE and pco2showed slight rises. Uterine perfusion was also slightly depressed by Complamin® addition. On the other hand no appreciable changes were noted in the fetal blood chemistry. Oxygen and Complamin® in conjunction caused a depression of perfusion similar to that observed with oxygen alone. The response of the fetal pH was significantly more favourable in the combined group than in the oxygen group, and po2rose, just as in the oxygen group. The conclusion may be drawn that oxygen ventilation of the mother in the final stage of gestation has an unfavourable effect on the fetal acid‐base balance. It seems possible that this effect is to some extent counteracted by Complamin® administration in conjunction with oxygen vent

ISSN:0001-6349    

DOI:10.3109/00016347309157086

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Blood flow in one uterine artery was measured by the electromagnetic flowmeter method in non‐pregnant women undergoing surgery. Due to difficulties in dissecting and exposing the uterine artery, statisfactory signals for estimating blood flow were obtained in only 10 out of 22 patients. Most of them had uterine myomas. Mean blood flow in one uterine artery was found to be 53.5 ml/min. After injection of oxytocin blood flow was reduced to 22 to 74% of controls, except in one patient, where no flow change was observed. Methergin administered in 3 patients caused no changes in uterine blood flo

ISSN:0001-6349    

DOI:10.3109/00016347309157087

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Amniotic fluid creatinine, uric acid and urea were measured by an automated method in 127 pregnancies. The concentration of each solute increased with gestational age. A creatinine concentration of 2.0 mg/100 ml could be used to pick up 52.9% of “mature” fetuses (i.e. fetuses which had passed the 37th week of gestation) but there was a false positive pick‐up of 5%. A uric acid concentration of 5.0 mg/100 ml correctly indicated a mature fetus in 41.5% of patients, the false positive pick‐up being 3.3%. Amniotic fluid urea was not a useful index of fetal m

ISSN:0001-6349    

DOI:10.3109/00016347309157088

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.A study of the clearance of133Xenon from the non‐pregnant human uterus is reported. The isotope was deposited in the uterus either by direct injection at a fixed depth from the endometrial surface in the uterine fundus or by injection into the uterine artery. With both types of injection multiexponential curves resulted. This is thought to reflect the existence within the uterus of compartments with different rates of perfusion. By conventional graphical separation of curve components two, sometimes three, components are identified. Their mean half‐times are after intraarterial injection in 15 cases 1.4 and 11.4 min respectively. After local injection in 10 cases 1.2 and 20 min respectively. A third very quick component was seen in carcinoma cases and was not calcula

ISSN:0001-6349    

DOI:10.3109/00016347309157089

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Using animal experiments, the authors studied the mode of action of F 6066 (Cyclofenil) which is one of the chemical inducers of ovulation, and reached the following conclusions. F 6066 has a dose‐dependent effect, enhancing the actions of gonadotropin in the ovary. The activity of steroidogenic enzymes, such as Δ5‐3β‐ol dehydrogenase, NAD‐, NADP‐diaphorase and glucose‐6‐phosphate dehydrogenase, was activated directly by the administration of F 6066 in hypophysectomized experimental animals. Therefore, F 6066 not only showed a biological action on the hypothalamo‐pituitary system promoting gonadotropin release, but also a direct action on the ovary enhancing the response of the gonad

ISSN:0001-6349    

DOI:10.3109/00016347309157090

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

Abstract.Sixty‐four samples of undialysed amniotic fluid were analysed in a free zone electrophoresis apparatus equipped with an ultra‐violet (UV) scanning attachment for quantitative determinations of the protein concentrations. Total protein concentrations were measured by a biuret method. The electrophoretic patterns of amniotic fluid were generally simpler than those from maternal or cord serum or plasma. The albumin fraction showed the highest correlation to total protein levels in amniotic fluid both in normal pregnancies and in pregnancies complicated by haemolytic disease. Samples from pregnancies complicated by moderate to serious haemolytic disease showed a tendency to a more rapid decrease of the main protein fractions during the later phase of pregnancy. No significant connections could be found between the main protein fractions and cord blood haemoglobin or bilirubin concentrations. A probably significant correlation existed between the values for the albumin fraction and the values for amniotic fluid bile pigments (ΔE450) in normal pregnancies but not in pregnancies with haemolytic disease. A high nonprotein peak in the patterns from amniotic fluid was found to consist mainly of uric acid. The size of this peak was positively correlated with infant birth weight and negatively correlated with concentrations of albumin and total protein in normal pregnancies. Polyacrylamide gel gradient electrophoresis of some samples showed amniotic fluid to be rich in proteins with relatively low molecular wei

ISSN:0001-6349    

DOI:10.3109/00016347309157091

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY