摘要:

Abstract.In a double‐blind, randomized trial, the antithrombotic effect and haemorrhagic complications of low molecular weight heparin (LMWH) (Heparin fragment 2165, KabiVitrum) and unfractionated heparin (UH) were compared. LMWH (5000 anti‐XaU) was injected every 24 h, UH (5000 IU) every 12 h; both drugs by subcutaneous injection. During 1984–85, 215 patients were examined clinically and by plethysmography. Venography was performed whenever DVT was suspected. None of the patients proved to have DVT. Bleeding complications were found in 54% of the cases. The LMWH group had a statisticaly significant predominance of bleeding complications as reflected by wound haematomas (p = 0.02) and the number of blood transfusions (p = 0.02). The heparin concentration was higher in the LMWH group (mean 0.13 IU/ml) than in the UH group (mean 0.13 IU/ml) measured 2 h after the injection. In the doses administered, LMWH and UH seem effective in the prevention of thrombosis. The increased bleeding tendency in the LMWH group probably was a concequence of the to high d

ISSN:0001-6349    

DOI:10.3109/00016348809004178

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.To evaluate whether long‐term human fetal exposure to 0‐adrenergic receptor agonists elicit alterations in the human fetal heart, a fetal echocardiographic examination was performed in 9 fetuses between the 24th and 35th week of gestation (median 28 weeks) and 9 age‐matched controls. Examinations were performed during long‐term tocolytic terbutalin treatment. Drug dosages varied between 7.5 and 20.0 mg/day (median 10.0 mg/day) and treatment durations prior to examination varied between 14 and 60 days (median 25 days). No significant differences were noted between the exposed fetuses and their controls as regards FHR, left ventricular dimensions, interventricular septal thickness, left ventricular contractility (fractional shortening) and the derived left ventricular stroke volume. Despite the limited number of subjects it is believed that long‐term terbutalin exposure does not have any untoward major fetal left ventricular con

ISSN:0001-6349    

DOI:10.3109/00016348809004179

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.In order to try to find a method for predicting pregnancy‐induced hypertension (PIH), the roll‐over test, isometric handgrip test and cold pressor test were performed on 40 healthy pregnant women in their 29th to 31st week of pregnancy. All these three tests proved positive (rise in diastolic pressure of at least 20 mmHg) in more than 50% of the subjects. None of the women in the study developed PIH (blood pressure 140190 or more on at least two consecutive occasions). These results indicate that none of these simple physiologic tests is of use as a predictor of

ISSN:0001-6349    

DOI:10.3109/00016348809004180

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.Pregnancy following a period of infertility was considered to be an increased risk for the fetus. During a period of 3 years (1983–85), 748 couples were seen at this infertility clinic; 515 women (68.9%) conceived, and were followed up and studied prospectively. Fifteen of these women moved out of the area. We analysed the results of pregnancies for the remaining 500, (Group 1) and compared them with the outcome for the total obstetric population (Group 2) during the same period. Mean age at conception in the infertility group (Group 1) was 31.8 (±2.7, 2 SD) years, as compared with 23.7 (±2.9, 2 SDI in the total hospital obstetric population (Group 2) (p>0.05). The incidences of spontaneous abortion for the two groups (8 and 6.2%) did not differ (p0.011. The incidences of infants with birth weight below the tenth centile (12.9%), of fetal distress in labor (14.6%) and a low Apgar score (0 – 5) (9.5%), were higher in Group 1, but there was no difference in the perinatal mortality rate between the two groups. In general, babies and mothers in the infertility group seemed to fare no worse than those in the total obstetric group delivered at our hospital. This may be because of the intensive antenatal, and intranatal care the patients receive in the infertility group under close supervision by one obste

ISSN:0001-6349    

DOI:10.3109/00016348809004181

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.9703 labors at Akershus Central Hospital during the period 1979 to 1984 were analysed to see which factors influenced the duration of labor. Median duration was 8.2 h for nulliparas, 5.3 h for multiparas. Parity greater than one had no influence on duration. Induced labors were 1.9 h (nulliparas) and 1.4 h (multiparas) shorter than those with spontaneous onset. Stepwise linear regression showed that duration of labor was positively correlated with the weight of the infant, duration of pregnancy, weight gain and prepregnant weight. It was negatively correlated with mother's height. Mother's age did not influence duration of labor. Occiput posterior presentation and extensions of the head prolonged labor in nulliparas, but not in multiparas, while breech presentation had no influence.

ISSN:0001-6349    

DOI:10.3109/00016348809004182

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.Life‐threatening obstetric or gynecologic hemorrhage can often be controlled by ligation of the uterine arteries or the internal iliac arteries. Following a description of the pelvic blood supply, the distribution and capacity of the collateral system and the hemodynamic changes after ligation, attention is called to these procedures of treatment and the consequent results, as described in the litterature. There IS no reason to fear tissue necrosis after ligation and knowledge of the abovementioned possibilities of ligation may contribute to the avoidance of unnecessary emergency hysterectom

ISSN:0001-6349    

DOI:10.3109/00016348809004183

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.Fetal head compression pressure (FHCP) and its clinical importance has been investigated in a group of 46 spontaneous births. Measurement of FHCP was facilitated using a compression transducer positioned between the fetal head and the wall of the birth canal. This method not only constitutes a means of quantitating the forces acting directly on the fetal head, but also provides information about the intracranial pressure generated during delivery. The latter extrapolation is based on the principle of applanation. The technique provides an objective and reliable estimate of intracranial strain and therefore a means of comparing the forces generated under different delivery modes. The condition of the same neonates at birth was assessed using umbilical artery pH, Apgar score, neurobehavioral testing and fundoscopic examination. The mean amplitude of FHCP in the different deliveries ranged from 38 to 390 mmHg (5–52 kPa) with an overall mean of 157.9 mmHg (21.1 kPa). The study indicated that the appearance of retinal hemorrhages in the newborn cannot be explained by exposure of the fetal head to abnormally high compression during birth. Other explanations must be sought for infants with a neurobehavioral deficit, reduced Apgar score, or umbilical artery acidosis at birth. It is concluded that a relatively short period of high FHCP has no obvious consequences for fetal well‐being, at least within the limits described in the present rep

ISSN:0001-6349    

DOI:10.3109/00016348809004184

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.Three hundred and sixty patients underwent hysteroscopy before entering the IVF program. The procedure was successful in 332 patients; obstructive tubal disease was pre‐ sent in 247 (70%); 148 showed uterine abnormalities (44.5%) such asendornetrial polyps, adhesions, hypoplasia, malformations, or severe cervical stenosis; 114 patients had normal hysterographic findings, in whom hysteroscopy revealed a false‐negative rate of 36.8%. In 281 patients (84.6%) hysteroscopy was carried out under general anesthesia, in most cases associated with laparoscopy. There were no anesthetic complications, uterine perforations or other significant problems. In an IVF program, hysteroscopic evaluation can reduce the failure rate due to intra‐uterine abnormalities. Hysteroscopy, which permits one to optimize an IVF attempt, becomes an essential procedure before introducing a patient into an IVF pr

ISSN:0001-6349    

DOI:10.3109/00016348809004185

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.In a group of 187 women, the result of the next pregnancy following a spontaneous first‐trimester abortion was studied, in relation to the interval between the two pregnancies. Conception within 3 months of the abortion gave no greater risk for another abortion than did conception after a longer interval (9/56 = 16% vs. 24/131 = 18%

ISSN:0001-6349    

DOI:10.3109/00016348809004186

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract.The effects of 554 non‐radical vaginal and abdominal hysterectomies on micturition symptoms and urinary incontinence were studied. From the urological point of view, two groups of women may be distinguished prior to hysterectomy: one without urological symptoms and the second with urological complaints (present in no less than 57% of all women and differing significantly from the distribution of urological symptoms in the normal population). In the first group, frequency developed significantly more often than nocturia, dysuria, stress incontinence and nocturnal and diurnal urge incontinence. The type of hysterectomy was not related to this development, except that urgency more often followed vaginal hysterectomy. In the second group, highly significant improvement and disappearance of symptoms was observed. Age, parity, menopausal status, the presence of myomas, height, weight and body mass index had no influenc

ISSN:0001-6349    

DOI:10.3109/00016348809004187

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY