摘要:

AbstractChanges in renal excretions of sodium (Na), potassium (K), and chloride (CI) upon a postural change from sustained recumbency to standing and walking were examined in 146 children with chance proteinuria and/or hematuria and in 27 children with biopsy‐proved diffuse mesangial proliferative glomerulonephritis (GN) including membranoproliferative GN (MPGN). Renal excretions of Na, K, and CI were inhibited in children with macroscopic hematuria and/or proteinuria and in those with moderate to severe mesangial proliferative GN and MPGN. Reductions in urinary Na/K ratios, reflecting the effect of aldosterone on renal tubular reabsorption, were noted upon a postural change, but there was no significant relation between the changes in urinary Na/K ratios and glomerular lesions. These results suggest that renal excretions of Na, K, and CI are simultaneously decreased upon an orthostatic postural change in children with severe mesangial proliferative GN and MPG

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00042.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

AbstractThe radioreceptor assay (RRA) of human growth hormone (hGH) was developed using liver microsomal fraction from estrogen‐treated female rats. The method allows measurement of physiological amounts of hGH (1.5–100 ng/ml) in unfractionated serum. Cross‐reactivity with human prolactin was 4.6%. Native hGH, recombinant methionyl‐hGH, and methionine‐free hGH showed a similiar binding to the receptors. Simultaneous determinations of serum hGH concentration with the RRA and radioimmunoassay (RIA) were performed in samples after the administration of GH‐releasing hormone (GRH) (1—44) from 15 normal short children and 25 patients with hGH deficiency. Overall RRA/RIA ratio in 146 samples was 0.84 ± 0.31 (SD). Of 15 normal short children, one showed a significantly reduced RRA/RIA ratio of 0.13 ± 0.03 in comparison with that of the other (0.70 ± 0.40) (p<0.001). His growth rate was accelerated by exogenous hGH administration, indicating that he secreted a biologically inactive hGH. The present RRA provides a useful method for screening bioinactive hGH in a large number of serum samples from children wi

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00043.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

AbstractA patient presenting with osteomyelitis of the pelvis is described. In this case it was difficult to establish a correct diagnosis by use of scintigraphic scanning, in spite of clear roentgenographic evidence of osteomyelitis.

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00044.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

AbstractA 10‐year‐old boy with anaerobic pyogenic liver abscesses due toBacteroides fragilisis reported. Blunt trauma was considered as the possible cause of the liver abscesses. Imaging methods such as ultrasonography, computed tomography and liver scannings were useful for the diagnosis of the case. The patient was cured after treatment with surgical debridement and drainage followed by a 10‐day course of intravenous Linco

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00045.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00046.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00047.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00048.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:1328-8067    

DOI:10.1111/j.1442-200X.1987.tb00049.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY