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1. |
The Effects of Anti‐Thymus Serum on Embryonic Development in the Rat |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 495-500
Koichiro Miyata,
Tamotsu Jitosho,
Junko Tachikura,
Tsutomu Haraguchi,
Shinji Suenaga,
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摘要:
AbstractPregnant Wistar rats were injected with rabbit anti‐rat‐thymus serum (ATS) alone or in combination with rabbit anti‐rat‐heart serum (AHS). The results showed that the percentage of malformation was low (5.7 to 7.5%) when doses over 0.6 ml/100 g of ATS were administered; resorption was 23.2 to 28.4%. However, the incidence of malformations markedly increased to 28.9% when a dose (0.9 ml/100 g) of ATS was given on day 9 of gestation followed by 0.9 ml/100 g of AHS on day 10. The resorption and cardiovascular malformations were 39.7% and 10.5%, respectively. These results suggest that ATS potentiates teratogenicity in combination with AHS, though hypoplasia of thymus was not o
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01854.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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2. |
Glomerular Basement Membrane Antigens in Various Renal Diseases in Childhood |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 501-509
Hiroshi Miyata,
Takashi Yamamoto,
Ryogo Murata,
Sunao Makai,
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摘要:
AbstractUrinary glomerular basement membrane (GBM) antigens were determined by radioimmunoassay in children with various glomerular diseases. The excretion of the GBM protein antigens was about one mg/g of urinary protein in most patients, except for patients with minimal change nephrosis. Although the GBM antigens were not uniform substances, the excretion of the GBM glycoprotein antigens was greatest in patients with membranoproliferative glomerulonephritis and rapidly progressive glomerulonephritis.
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01855.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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3. |
Clinicl Significance of Mesangial IgM Deposits in Minimal Change Nephrotic Syndrome |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 510-519
Norishi Ueda,
Takehiko Yasaki,
Yukihiko Niinomi,
Toru Nonoda,
Masazumi Ohnishi,
Seizo Iwayama,
Aiko Mizuno,
Shigemitsu Ito,
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摘要:
AbstractThe clinicopathologic features and the response to corticosteroid therapy were compared in 9 patients with minimal change nephrotic syndrome (MCNS) and diffuse mesangial IgM deposits (Group I) and in 32 of those without IgM deposits (Group II).However, serum IgM levels in Group I in both relapse and remission were significantly higher than those of Group II and controls (p<0.001).In Group I mesangial IgM deposits were diffuse in 9 (100%), mesangial C1qwas present in 4, IgA and fibrinogen were each observed in 1, respectively. Electron dense deposits in the mesangium were also present in 2 to 5 patients in Group I.No significant differences were found between the two groups in age of onset, sex ratio, laboratory data except for serum IgM level, duration before biopsy, follow‐up periods, outcome, and response to steroid therapy.Our data suggest that a more severe degree of either impairment of mesangial clearance of IgM or overproduction of IgM may be involved in patients with MCNS and mesangial IgM deposits but that these patients could not be considered a distinct group of patient
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01856.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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4. |
Right Pulmonary Artery Measurements in Term and Preterm Neonates during the Early Newborn Period: Hemodynamic Correlation and Clinical Significance |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 520-527
Edgardo E. Ortiz,
Kouki Oguchi,
Hitoshi Misawa,
Youtaro Agata,
Satoshi Hiraishi,
Hiroshi Nishida,
Kimio Yashiro,
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摘要:
AbstractRight pulmonary artery (rPa) diameter was measured during the first hour of life, then during the next 23 hours, at 72 hours and at 120 hours in 62 normal term and 14 normal preterm neonates by M‐mode echocardiography via the suprasternal notch. Left atrium (LA) and aortic (Ao) diameters were likewise determined from the standard parasternal view. Comparison was also made with rPA values of 34 patients with patent ductus arteriosus (26), persistent fetal circulation (6) and cyanotic congenital heart disease (2).In normal term babies, the mean rPA size changed significantly during the 4 periods of examination with diameters of 4.6 mm, 5.5mm, 5.2mm and 4.7 mm respectively. Among preterm babies, mean rPA diameter at 24 hours was 3.8 mm, at 72 hours, 3.8 mm, and at 120 hours, 3.3 mm. unlike those in term babies, the changes in preterm babies were not significant. LA dimensions and LA/Ao ratio were more variable. Furthermore, rPA measurements reliably differentiated clinical conditions with increased or decreased pulmonary blood flow. Thus, our data confirm the significance of rPA measurement as it closely correlates with the hemodynamic changes in the early neonatal period in normal and abnormal term and preterm babie
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01857.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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5. |
A Clinicl Picture of Aseptic Meningitis as Portrayed from a Study of 150 Patients During Three‐Year Observation |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 528-533
Ikuko Yui,
Jun Watanabe,
Yoshinao Takeuchi,
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摘要:
AbstractOne‐hundred and fifty patients with aseptic meningitis were studied in order to investigate their clinical manifestations and cerebrospinal fluid (CSF) contents. The patients were classified according to causative organisms and/or associated diseases. Hypoglychorrhachia was found in nearly half of the total CSF samples from patients with mumps meningitis. A coxsackie virus was isolated from a CSF specimen from one patient who had typical meningeal signs but had no pleocytosis (so‐called meningi
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01858.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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6. |
Authoritarian Paternal Attitude Inter‐Generational Transmission |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 534-538
Peter O. Peretti,
Jo Ann Statum,
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摘要:
AbstractThe present research was conducted to determine authoritarian paternal attitude inter‐generational transmission. Factor analysis of the results suggested that authoritarian paternal attitudes could be indicated in terms of five factors, namely: Dominant, Rigidity, Conformity, Intoleratn, and Uncreative. In general, the sons expressed strongly the authoritarian attitudes of the fathers. Moreover, there were few significant differences Between the paternal attitudes of the fathers and son
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01859.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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7. |
Munchausen's Syndrome in Children: Bizarre Clinical and Laboratory Features |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 539-543
Kazuo Abe,
Kazunori Shinozima,
Akihiro Okuno,
Takeshi Abe,
Hitoshi Ochi,
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摘要:
AbstractA 10‐ year‐old girl showed macroscopic hematuria, purpuric rash, bloody stool and complained of abdominal pain and joint pain for three years. The extensive investigations including intravenous urography, cystoscopy, barium enema, upper gastrointestinal X‐rays, sigmoidoscopy and renal biopsy failed to reveal the sources of bleeing for urinary anmd gastrointestinal tracts and to explain abdominal and joint pains. the major blood group of the patient was B, while that in the urine obtained by the patient without supervised conditions was A or AB. This finding indicated that macroscopic hematuria was factitious in origin and the patient stated that symptoms were fabricated by herself.The various psychological tests failed to disclose the motives for this bizarre behavior and to obtain the evidence of psychosis.This case presents the youngest and fourth case of Munchausen's syndrome in children and suggests that when bizarre clinical and laboratory findings are observed, Munchausen's syndrome should be suspected and its consideration may obviate harmful and unnecessary investigations as well as medica
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01860.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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8. |
Type IIB von Willebrand's Disease: Report on the First Case in Japan |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 544-553
Hiromu Fukui,
Motoshi Yasui,
Yukihiro Takahashi,
Kou Niinomi,
Toshio Takase,
Akira Yoshioka,
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摘要:
AbstractThree members of a family are reported with type IIB von Willebrand's disease (vWD), characterized by prolonged bleeding time, increased ristocetin‐induced platelet aggregation, fast anodal migration of factor VIII‐related antigen on crossed immunoelectrophoresis and an absence in plasma and presence in platelets of the larger multimers of factor VIII/von Willebrand factor (FVIII/vWF). Binding ability of the patient's FVIII/vWF to washed normal platelets is significantly increased in the presence of low concentrations of ristocetin, whereas binding ability of the patient's platelets to normal FVIII/vWF is not increased. These later findings are contrary to those in patients with pseudo‐vWD or platelet type vWD. The administration of DDAVP gives a shortening of bleeding time and an increase in plasma levels of factor VIII‐related activities. In addition, there is a transitory appearance of the larger multimers and a moderate diminution of the platele
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01861.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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9. |
Congenital Hypoprothrombinemia: The First Reported Case in Japan |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 554-560
Yoshihiro Fujimura,
Noriko Nakaue,
Mitsuhiko Sugimoto,
Ikuko Matsuyama,
Toshio Takase,
Akira Yoshioka,
Hiromu Fukui,
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摘要:
AbstractA Japanese boy with congenital hypoprothrombinemia, who was discovered in the newborn period when umbilical bleeding occurred, is described. On the 6th day after birth, the patient was found to have a markedly low thrombotest and prolonged prothrombin time and partial thromboplastin time. The administration of vitamin K failed to correct the coagulation defects, and the specific coagulation and immnological assay disclosed an extreme decrease of prothrombin activity and antigen. A slight increase of prothrombin activity and antigen in the patient was observed during the first year of life. The half‐lives of prothrombin activity and antigen were both10–11 hrs in the first phase, and32–33 hrs in the second phase. The inheritance mode of the disease seemed to be an autosomal recessive from the test results of the family me
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01862.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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10. |
Transient Neonatal Hyperphenylalaninemia due to Immature Development of 7, 8‐Dihydrobiopterin Synthesis |
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Pediatrics International,
Volume 26,
Issue 4,
1984,
Page 561-564
Yoshitomo Sawada,
Haruo Shintaku,
Gen Isshiki,
Yutaka Hase,
Tsuneo Tsuruhara,
Toshiaki Oura,
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摘要:
SummaryWe describe a case with transient neonatal hyperphenylalaninemia, possibly due to immature biosynthesis of 7, 8‐dihydrobiopterin (BH2). In the neonatal period his blood phenylalanine levels were high and the patterns of urinary pterins were similar to those found in defective synthesis of BH2, which results in a type of hyperphenylalaninemia. But the laboratory data became almost normal after three months. Transient hyperphenylalaninemia has generally been thought to be caused by the delayed maturation of phenylalanine hydroxylase. But it is suggested that some cases with transient neonatal hyperphenylalaninemia are due to immaturity of BH2cofactor biosynthesis rather than that of phenylalanine hydroxylas
ISSN:1328-8067
DOI:10.1111/j.1442-200X.1984.tb01863.x
出版商:Blackwell Publishing Ltd
年代:1984
数据来源: WILEY
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