ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01053.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

During the period 1966‐1985, 66 patients were submitted for curative treatment of a carcinoma of the base of the tongue in the Netherlands Cancer Institute. Treatment consisted of radiotherapy (59 patients), surgery and post‐operative radiotherapy (4 patients) and surgery alone (3 patients).Patients were staged according to the UICC (1982) and UICC (1987)/AJCC (1988) criteria. Regrouping by the latter system caused enlargement of the N2‐group and of stage IV.The crude 5‐year survival was 22%, the 5‐year tumour control was 36% and the locoregional control was 47%. The most important prognostic factors for the tumour‐free interval are the T‐category (P =0.01) and stage grouping (UICC 1982)(P =0.022). The same factors predict the locoregional control (P =0.005 and 002 respectively). Crude survival is lower in smokers, and in patients in poor general condition (P =0.04 and 0.007

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01054.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

The treatment of temporal bone carcinoma is a widely discussed topic with marked variation in published results. Most conclude that a combination of radical surgery and radiotherapy is the optimum treatment.The present study reviews the results of radiotherapy used as the main primary treatment for this condition. Five‐year survival in 56 patients was 32% for radical and palliative therapy, with an excellent response in ‘early’ cases.It is concluded that improvement in survival could be attained by defining those groups which would benefit from a combination of treatment me

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01055.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

A prospective study of auditory function in 18 HIV positive male patients at different CDC (Centres for Disease Control) stages was undertaken. One‐third had abnormalities on either auditory evoked response testing or pure tone audiometry. No correlation was found between interwave latencies I‐V, I‐III, III‐V and stage of disease determined either clinically or by T‐cell subset. There was a weak correlation between pure tone averages at 1,2,4 kHz and 2,4,8 kHz and T‐cell subset ratio in CDC Group IV disease (Rs= 0.56 and 0.57 respectively;P<0.05). Abnormalities of BSER were similar to those previously reported in HIV infection, and suggest isolated changes within the

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01056.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Endoscopic treatment of a hypopharyngeal diverticulum was performed in 75 patients during the period 1976‐1990. Initially electrocoagulation was used to divide the septum between the diverticulum and oesophagus. More recently, the CO2laser combined with the operating microscope has been used. Although this has reduced the need for multiple endoscopic procedures compared to the electrocoagulation technique, this reduction was not statistically significant. In our follow‐up group of patients, 49 (72.7%) were highly satisfied and 14 (19.6%) fairly satisfied. In this respect no significant differences between the electrocoagulation and laser group were found. Although we consider the use of the CO2laser and operating microscope as a technical improvement of the former Dohlman procedure, further assessment needs to be done to evaluate whether laser therapy docs offer an improvement in resu

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01057.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Nasal ciliary function forms an important defence mechanism within the upper respiratory tract which has largely been ignored in recent years. The effects of various drugs used extensively in the treatment of diseases of the nose have not been fully established. Furthermore, the physiological control of ciliary activity is unclear. The aim of this study was therefore to investigate the effects of drugs on ciliary beat frequencyin vitrousing a photometric technique. A dose‐dependent response to α and β receptor drugs was found, cocaine hydrochloride achieved ciliostasis even at 40‐fold dilution, and potassium ions, except at the limits of tolerance for excitable tissue, did not affect ciliary function. In conclusion, we suggest that α and β receptors may be present on ciliated epithelium and be involved in the control of ciliary functionin vivo.Ion fluxes across the ciliary cell membrane may also be important in ciliary activity akin to nervous

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01058.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

This paper investigates distress in 221 children admitted to a district general hospital for ENT surgery. Younger children (5 years and under) were rated by nurses as being most distressed, with girls more so than boys. Presence of a parent in hospital overnight is also found to be associated with higher levels of distress. It is suggested that preparation programmes designed to reduce distress should target younger children and that consideration be given to a preparation programme for parents.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01059.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

The change in nasalance following adenoidectomy, tonsillectomy and adenotonsillectomy was studied in 44 children. A subjective assessment of each child's naso‐pharyngeal airway was made preoperatively based on a questionnaire completed by the parents. There was no significant change in the nasalance of children following adenoidectomy, but there was a significant increase in the nasalance following tonsillectomy (P = 0.02) and after adenotonsillectomy (P = 0.001). There was no relationship between the change in nasalance and the adenoid volume removed at operation. There was good agreement between the parental subjective assessment of the naso‐pharyngeal airway and the preoperative nasalance score, with the best correlation in the adenoidectomy group (r = ‐0.8) and the adenotonsillectomy group(r = ‐0.7). Nasalance is more closely related to the size of the naso‐pharyngeal airway than to the actual adenoid volume, and measurements of nasalance are of no benefit in predicting adenoid volume. Tonsillectomy had a significantly greater effect on nasalance than adenoidectomy, and adenotonsillectomy had the greatest effect. Further studies are needed to relate nasalance to the size of the naso‐pharyngeal airway, but it appears to relate well to the subjective assessment of the airway and may be of use in patient selection

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01060.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

A new endoscopic method of measuring the cross‐sectional area of a subglottic stenosis is presented. The method was tested against existing techniques using a model.By standardizing the distance from the objective of the endoscope to the stenotic area we were able to measure the cross‐sectional area using a graduated grid held against the video screen. This technique was then compared with the standard one of estimating the diameter of a stenosis from the external diameter of the bronchoscope which can be passed through the stenosis. The methods were found to be equally accurate in measuring the lumen diameter. However, when measuring the minimum cross‐sectional area, three of five observers were significantly better (P<001) using the photometric method rather than the standard method (Wilcoxon's rank sum test for paired data). The photometeric technique of measuring the cross‐sectional area of the subglottis is easily performed, non‐traumatic, and allows a visual record t

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01061.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

This study aims to determine whether the implementation of a direct referral service in which family practitioners received feedback on the appropriateness of their patient selection had any impact on the referral pattern.Six months after the establishment of such a service to which general practitioners were requested to refer patients who satisfied the Hearing Aid Council and Therapist Technicians and Scientists in Audiology group criteria, 40 consecutive patients were analysed. 40 age matched controls referred concurrently to the routine ENT clinic for hearing aid provision were compared. In the 80 ears seen in each group, the number of perforations infected or otherwise were 2 and 7 respectively (P<0.01). Conductive hearing losses were more common in the control group (P<0.05).The degree of patient selection was higher than noted in the first 6 months of the service when the prevalence of perforations in the direct sample was 7%. It appears that the practice of selective referral has developed.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1992.tb01062.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY