ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02118.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

The endolymphatic surface of the stria vascularis in the guinea‐pig and the effects of ethacrynic acid as shown by scanning electron microscopyExamination of the endolymphatic surface of the stria vascularis showed, in agreement with previous studies, the marginal cells to be hexagonal in shape and that most possessed microvilli. However, the cells in the apical turns were more profusely covered with microvilli than those at the base and, particularly in the basal turns, there was some variation in the surface detail of the cells. These results may indicate differences in the physiological state of the cells. In the early period of ethacrynic acid intoxication (15–30 minutes post‐injection), when rapid changes in endolymphatic potential and ion‐fluxes occur, the surface of the marginal cells showed only slight distortion. The most dramatic changes were noted 1 hour post‐injection, and involved swelling of the cells and loss of microvilli. This distortion persisted up to 2 hours post‐injection. The possible explanation for these findings i

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02119.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

The factors which determine the viability of a triangular skin flapExperiments were undertaken on pigs to compare the survival of triangular flaps with rectangular flaps and to study the effect of the size of the apical angle on the survival of triangular flaps. Triangular random flaps survived to the same length as rectangular flaps of the same size of base, and its appears that length to breadth ratio is an important factor in determining the survival of a rectangular flap. Flaps with an apical of 60oundergo necrosis if their length exceeds the safe surviving length for the size of the base of the flap, whereas flaps with an apical angle of 300survive if their length is within the surviving length for flaps of that size of base. The main effect of the apical angle may thus be to determine the length to breadth ratio.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02120.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Vocal cord function following short term endotracheal intubationThis study was undertaken to determine whether brief periodsofvocal cord paralysis might commonly occur as a result of tracheal intubation. The vocal cords of 100 patients were examined prior to and after intubation for operation. Although soft tissue trauma was observed in nearly all patients none had evidence of vocal cord paralysis.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02121.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Direct bone invasion in squamous carcinomas of the head and neck: pathological implicationsDirect bone invasion by tumour–an uncommon event at most sites–has been demonstrated in 18 out of 150 consecutive major surgical specimens from patients with squamous carcinomas of the head and neck. Intra‐oral carcinomas invading the jaw(s) comprise the single commonest group. The tumour gains access to bone by direct spread or along perineural spaces: infiltration of periosteal lymphatics was rare. The morphological phasesofbone invasion are described, the main feature being bone destruction by osteoclasts in front of the advancing tumour; tumour cells do not directly impinge on the bone surface until the late stages of invasion. Osteoblastic activity is less marked. Evidence that osteoclasts are directly stimulated by local tumour is discussed. The clinical implications relate to the possible uses of scintigraphy and the need to ensure adequate bone resections in operable lesions: the tumours sometimes infiltrate laterally beneath apparently intact bone cortex (cf. submucosal spread), and the normal tissue planes at the bone‐soft tissue interface are usually distorted by previous radio

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02122.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Round window membrane rupture and acquired sensorineural hearing loss in childrenThe aetiology of acquired sensorineural hearing loss includes many conditions. The disparity between the number of children affected by the conditions which are supposed to cause hearing loss and the number of children who are actually deaf, has never been satisfactorily explained. Clinical features observed in children with surgically proven round window membrane rupture have been noted in all conventional aetiological groups. These features include otitis media, doubt about the hearing status in early life, disturbance of balance and other occasional neurological phenomena. Wide variation in the appearance of round window niche has been observed in children with secretory otitis and similar appearances have been observed in children with proven round window membrane rupture. The appearances may represent a reaction to perilymph. Round window membrane rupture is probably common and may prove to be a unifying factor for many cases of acquired sensorineural hearing loss. Occasional neurological phenomena may be related to it.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02123.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Age and mortality in laryngeal cancerA sample of 371 patients with squamous cell carcinoma of the larynx treated over a 17‐year period has been statistically analysed. Age is shown to be an important prognostic parameter. Apart from the well‐established additional risk factors, such as fixed cord, extension of the tumour beyond the larynx, fixed lymph nodes, distant metastasis and other malignancies, age by itself seems to be a crucial factor. A significant correlation exists between the age of the patient on admission and the chance of death from tumour within the first 3 years after treatment. In older patients survival is significantly lower and shorter than in younger patie

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02124.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02125.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02126.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Book reviewed in this article:Noise and Audiology edited by D. Lipscomb.Tumours of the Head and Neck by J.G. Batsakis.Clinical Otolaryngology edited by A.G.D. Mann&P.M. Stell.Diseases of the Ear by Stuart R. Mawson&Harold Ludman.JOURNAL REVIEW: The American Journal of Otology edited by M.E. Glasscock&Brian C. Decker.Atlas of the Histopathology of Ear Tumours

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1980.tb02127.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY