ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02029.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Assessment of the effect of chemotherapy and radiotherapy on the auditory function of children with cancerForty children with malignant disease underwent full audiological assessment with pure tone audiometry, tympanometry and measurement of brain stem auditory evoked potentials in an attempt to detect auditory dysfunction resulting from treatment. Significant auditory dysfunction was observed in 8 children. Three children with evidence of a conductive or sensorineural deafness on pure tone audiometry had normal brain stem evoked potentials. One child with a high tone hearing loss and 4 children with no detectable hearing loss on audiometry showed significant differences in the interaural interpeak latencies of selected brain stem auditory evoked potentials. In 2 children these abnormalities had resolved on subsequent testing, 2 had evidence of persistent retrocochlear dysfunction and the remaining child died prior to further evaluation. Routine measurement of brain stem auditory evoked potentials is probably not necessary for the majority of children undergoing treatment for cancer, although such measurements are of value when differentiation between cochlear and retrocochlear damage is required.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02030.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Studies on the mechanics of the reconstructed human middle earUsing a laser‐Doppler interferometer the influence of different positions of an incus prosthesis on hearing performance was examined in human temporal bone preparations. The influence of position and tension of a malleus to footplate prosthesis (columella) was studied in the same way. It is concluded that an incus prosthesis should be placed along an imaginary line through the centre of the footplate and the head of the stapes. With a malleus to footplate prosthesis the position on the footplate is relatively unimportant. Tension between the malleus, prosthesis and footplate, however, is quite important and should be as low as possible, and compatible with a stable situation. The malleus to footplate prosthesis provides a columella type of prosthesis which for lower frequencies works better than an incus prosthesis, and occasionally even better than the normal ea

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02031.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Laryngeal papillomas: classification and courseSeventy‐one cases of laryngeal papillomas have been reviewed. Based on differences in age at presentation, female: male ratio and multiple versus solitary papillomas, the cases were classified into 4 groups: multiple juvenile papillomas, solitary juvenile papillomas, multiple and solitary adult papillomas. The clinical course in the groups is described. The authors do not support the common opinion that juvenile papillomas are influenced by pubert

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02032.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Tinnitus in childhoodNinety‐three healthy children attending routine school and community medical examinations were questioned about tinnitus, 27 of them (29%) described tinnitus. Nine children (9.6%) were bothered by their symptom, the others were not. The incidence of tinnitus in this group was compared with that in a group of 109 children with ear disease. Forty‐two children (38.5%) in this group reported tinnitus. This difference is not statistically significant. Details of children attending paediatric ENT clinics were recorded by two ENT surgeons. Four hundred and three children were seen during the study period and of these 13 (3%) reported tinnitus spontaneously. All these children had evidence of ear disease at the time of the consultation. The incidence of tinnitus in those members of this group with abnormal ears was significantly higher than in those children with no evidence of ear disease (P=<0.02). Tinnitus may be a manifestation of ear disease in children, but may also be described by children with normal e

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02033.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

A systematic approach to parathyroid surgeryIn the last 8 years 33 patients with hyperparathyroidism have been surgically treated by the authors. Thirty patients had primary, 2 secondary and 1 tertiary hyperparathyroidism. In the 30 patients with the primary disorder, 26 had a single adenoma and 28 of these patients had normal calcium levels postoperatively. Two patients were hypocalcaemic following surgery and required calcium supplements for 3 months and 9 months respectively. It is recommended that when a single adenoma is found its removal will render the patient normocalcaemic. When all 4 glands are hyperplastic the surgery should be subtotal (3^ glands) parathyroidectomy except in the case of secondary hyperparathyroidism when total parathyroidectomy with autotransplantation and cryopreservation of the remainder should be performed.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02034.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Inner hair cell loss and intracochlear clot in the preterm infantLittle is known about the pathological changes in the cochlea of preterm infants which might be responsible for the hearing loss which the infants are at risk of developing. This study looks at the cochleas of 5 preterm infants who died at ages up to 2 weeks using light and electronmicroscopic techniques, and shows changes in the inner hair cell population in association with intracochlear clot which may be responsible for subsequent hearing loss.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02035.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Results of treatment with alpha‐interferon in adult‐onset laryngeal papillomatosisJuvenile laryngeal papilloma occurs mainly in childhood, but is also occasionally seen in adults. The treatment of this disease has been very unsatisfactory. During the last decade, vaporization of the papillomas with the carbon dioxide laser has been the most frequently applied method of treatment, but recurrences are often observed. Alpha‐interferon seems to affect the clinical course of juvenile laryngeal papillomatosis in children. We therefore started treating 3 patients with persistent adult‐onset laryngeal papillomatosis with alpha‐interferon in combination with regular endoscopic removal using the C02laser. In 1 case a complete remission occurred within 3 months. Administration of alpha‐interferon was continued for another 6 months. Laryngoscopy in the 2 other patients showed only minor lesions after treatment with alpha‐interferon for 1½ years. Alpha‐interferon treatment is still being continued. The dramatic improvement in the laryngeal picture of these patients during the treatment with alpha‐interferon leads to the conclusion that alpha‐interferon can affect the course of this disease. Whether a definite cure can be achieved is, however

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02036.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Antroscopy: its place in clinical practice. A comparison of antroscopic findings with radiographic appearances of the maxillary sinusOne hundred and fifteen patients with chronic nasal symptoms underwent both radiological and antroscopic investigation of their maxillary sinuses. A total of 193 antra were studied. The radiological diagnosis completely correlated with the antroscopic findings in only 44% of the cases. The reasons for this discrepancy are discussed as well as the additional limitations of radiology in the diagnosis of the opaque antrum and the accurate detection of sinus fluid. Antroscopy provides accurate information about the nature of mucosal changes, the presence of secretions and the state of the natural ostium. This technique therefore ensures a precise diagnosis on which appropriate primary treatment can be based as well as offering the most reliable means of selecting patients who require surgery. The potential for detecting early antral tumours is stressed. It is concluded that antroscopy is the most useful investigation in the management of chronic conditions of the maxillary sinus. However, radiology still has its place as a primary screening test, particularly when the radiographic findings are negative.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02037.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Cervical lymph node metastases with occult primaryPatients with cervical metastases from an unknown primary tumour present both diagnostic and therapeutic problems. Twenty patients with a metastatic lesion in the neck, in whom the primary tumour was not found despite extensive, diagnostic procedures, were treated in the Department of Otolaryngology, Linköping University Hospital, during a 14‐year period (1971–1984). Since 1975 tonsillectomy has been performed regularly on the affected side as a part of the diagnostic procedure. Eight patients without any clinical signs of a tonsillar primary have been diagnosed to have carcinoma by tonsillectomy and careful examination of the serially sectioned tonsillectomy specimen. The diagnosis of the metastatic nodes was based on histo‐pathological examination in 8 patients and on fine needle aspiration cytology in 12. Four of 9 patients with squamous cell carcinoma survived 3 years and so did 4 of 5 with anaplastic carcinoma. All 5 patients treated surgically are alive and 6 of 12 who were irradiated. Ten of 12 patients with mobile unilateral nodes (Nl) were alive at follow‐up after 1–13 years but only 3 of 8 patients with fixed nodes (N3) at follow‐up

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1986.tb02038.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY