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11. |
Six year multicenter surveillance of invasive pneumococcal infections in children |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 141-147
SHELDON KAPLAN,
EDWARD MASON,
ELLEN WALD,
TINA TAN,
GORDON SCHUTZE,
JOHN BRADLEY,
LAURENCE GIVNER,
KWANG KIM,
RAM YOGEV,
WILLIAM BARSON,
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摘要:
Objective.Monitor clinical and microbiologic features including antimicrobial susceptibility of invasive pneumococcal infections among children.Design.A 6-year (September, 1993, through August, 1999) prospective surveillance study of all invasive pneumococcal infections in children.Patients.Infants and children cared for at eight children’s hospitals in the United States with culture-proved invasive pneumococcal infection.Results.During the 6-year period 2581 episodes of invasive pneumococcal infection occurred in 2498 children. Underlying conditions were present in 29% of the children. Of children without an underlying condition, 15% of the total infections occurred in those 25 to 60 months old. As the ages of the children advanced the proportion of cases classified as bacteremia declined, whereas the proportion classified as pneumonia increased. Also, as the ages of the children increased the proportion of isolates in serotypes/serogroups 1, 3 and 23 increased. whereas the proportion for serotype 14 diminished. During the 6 years of the study, there was a significant increase in the percentage of isolates intermediate or resistant to penicillin (P< 0.000001) or intermediate to ceftriaxone (P< 0.002). By the sixth year of the study, 37 and 11% of the isolates were nonsusceptible to penicillin or ceftriaxone, respectively. Antibiotic use in the 30 days before diagnosis of systemic pneumococcal infection occurred in 30 to 35% of the children for each of the 6 years. The overall case-fatality rate for children with systemic pneumococcal infection was 1.56%. Mortality was greatest in children >60 months old and in those with underlying conditions; mortality was not related to antibiotic susceptibility.Conclusions.The percentage of pneumococcal isolates recovered from children with systemic infection which were intermediate for penicillin or ceftriaxone or resistant to penicillin increased steadily during the 6-year period. There was also a trend toward increasing rates of resistance to ceftriaxone. The age and serogroup/serotype distributions of our patients support the recommendations to consider administration of the seven valent pneumococcal conjugate vaccine for all children 24 to 59 months old, with special consideration for selected groups.
ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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12. |
Announcements |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 147-147
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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13. |
Epidemiology and clinical presentation of respiratory syncytial virus infection in a rural area of southern Mozambique |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 148-155
MARIA,
LOSCERTALES ANNA,
ROCA PERE,
VENTURA FÁTIMA,
ABACASSAMO FRANCISCO,
SANTOS MARIANO,
SITAUBE CLARA,
MENÉNDEZ BRIAN,
GREENWOOD JUAN,
SAIZ PEDRO,
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摘要:
Background.Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection (LRTI) in infants throughout most of the world, but little is known about RSV infection in Africa where LRTI are among the leading causes of infant and childhood death.Methods.The study took place in a rural district hospital in southern Mozambique between October, 1998, and May, 2000. From all children (n= 5635) <1 year of age presenting to an outpatient department with cough or nasal secretion and all children (n= 1307) <5 years of age admitted to hospital with a LRTI, a nasopharyngeal aspirate was collected and tested for RSV by enzyme-linked immunosorbent assay (Abbott).Results.RSV infection was found in 8.6% of study infants in the outpatient department and 10.6% of admitted children with LRTI. Cases presented in predictable yearly outbreaks during the warm and rainy season. Lower respiratory tract involvement was frequent (59.7%). Cough, chest indrawing and increased respiratory rate were all independently related to RSV infection. Wheezing was infrequent. Bacterial coinfection (4.6%) and the case-fatality rate (3.4%) were low.Conclusions.There is a substantial burden of disease attributable to RSV infection in this rural African setting, with the highest incidence and severity occurring in young infants.
ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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14. |
Management of typhoid fever in children |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 157-159
Ina,
Stephens Myron,
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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15. |
Immunization in transplant patients |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 159-160
Margaret,
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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16. |
Trichosporonosis, an unusual fungal infection in neonates |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 161-165
GUILLERMO,
SALAZAR JUDITH,
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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17. |
Streptococcus pyogenespyomyositis |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 166-168
SOPHIA,
ZERVAS LAWRENCE,
ZEMEL MARK,
ROMNESS EDWARD,
KAPLAN JUAN,
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摘要:
Group A beta-hemolyticStreptococcuspyomyositis continues to be an uncommon disease. We present a case of a 7-year-old boy with an M protein type 1, streptococcal pyrogenic exotoxin A and B,Streptococcus pyogenespyomyositis and streptococcal toxic shock syndrome.
ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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18. |
TRICHOSPORON ASAHII: AN UNUSUAL CAUSE OF INVASIVE INFECTION IN NEONATES |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 169-170
Paraskevi,
Panagopoulou Joanna,
Evdoridou Evangelia,
Bibashi Joanna,
Filioti Danai,
Sofianou George,
Kremenopoulos Emmanuel,
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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19. |
CHRONIC VULVOVAGINITIS CAUSED BY ANTIBIOTIC-RESISTANTSHIGELLA FLEXNERIIN A PREPUBERTAL CHILD |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 170-172
Maria,
Baiulescu Patricia,
Hannon John,
Marcinak William,
Janda Paul,
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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20. |
GLOMERULONEPHRITIS AFTER RECOMBINANT HEPATITIS B VACCINE |
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The Pediatric Infectious Disease Journal,
Volume 21,
Issue 2,
2002,
Page 172-173
Marco,
Pennesi Giuliano,
Torre Manuela,
Del Santo Aurelio,
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ISSN:0891-3668
出版商:OVID
年代:2002
数据来源: OVID
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