ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Pseudomonas aeruginosa skin infections are generally considered to be secondary manifestations of disseminate disease. A retrospective analysis of all cases ofP. aeruginosaskin infections seen at St. Jude Children's Research Hospital since 1962 revealed 16 episodes of the infection (ecthyma gangrenosum, 8 episodes, 7 patients; cellulitis, 8 episodes, 7 patients) in which blood cultures were uniformly negative forP. aeruginosa.All cases were identified while the patients were receiving ambulatory care. Five episodes developed while the patients' neutrophil counts were greater than 1 x 109cells/liter. Eight patients had acute lymphoblastic leukemia, 2 had acute myeloid leukemia, 2 had aplastic anemia, 1 had transient agranulocytosis and 1 had cyclic neutropenia. There were no solid tumor patients. Although patients received different antibiotic combinations, all had resolutions of their lesions without fatal complications. Patients diagnosed as having cellulitis required a mean of 9.2 days of treatment with intravenous antibiotics, as compared with 17.8 days for those with ecthyma gangrenosum (P< 0.05 by the Wilcoxon test). These observations show thatP. aeruginosaskin infections can develop in the absence of bacteremia in immunocompromised children.

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

This double blind, placebo-controlled trial was designed to determine whether intervention with a stepped regimen of trimethoprim-sulfa-methoxazole (TMP-SMX) and prednisone would prevent high risk children from developing chronic otitis media with effusion (OME) and recurrent acute otitis media. Forty-two children were enrolled, assigned to treatment with active drug or placebo and then examined at 2-week intervals. They received TMP-SMX (or placebo) during the first 2 weeks, TMP-SMX and prednisone (or placebo) during Weeks 3 and 4 for persistent OME and TMP-SMX (or placebo) for Weeks 5 and 6 if OME was still unresolved. After treatment 48% of active drug and 14%.

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

To assess the incidence of bacteremia in pediatric cancer patients with indwelling central venous catheters with fever, we reviewed the records of all 67 such patients sequentially admitted during a 10-month period at our institution. There were a total of 140 episodes of fever in these 67 patients. In 55 of the episodes (39%) patients were nonneutropenic (absolute neutrophil count, >500/mm3); 85 episodes (61%) were associated with neutropenia. Twenty-four percent of all episodes of fever in nonneutropenic patients were related to bacteremiavs.9.5% of episodes of fever in the presence of neutropenia (P≤ 0.05). When clinical evidence.

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

During a 16-month study period at a children's hospital, 32 children developed nosocomial gastroenteritis caused by astroviruses. Twenty-five of these occurred during 2 epidemic outbreaks in medical and surgical infants' wards. From the community, 13 confirmed cases were admitted during the study period. Both community-acquired and nosocomial cases occurred during autumn, winter and early spring. The atack rates during outbreaks ranged between 7 and 62% and were highest among children with underlying gastrointestinal diseases. Diarrhea and vomiting were the most common clinical manifestations. The median duration of symptoms was 4 days and that of virus excretion was 5 days.Hospital infection with astroviruses is common and usually affects children less than 2 years of age. The probable mode of transmission is spread via contaminated hands.

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1991

数据来源: OVID