ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

We report seven patients with chronic recurrent multifocal osteomyelitis, an uncommon childhood disease of unknown etiology. These patients presented with insidious onset of bone pain at one or more sites associated with erythema, swelling and tenderness. Scintigraphy and radiography were consistent with osteomyelitis at multiple sites. Bone biopsies confirmed osteomyelitis but no organisms were consistently isolated. During a 1− to 3-year follow-up, most patients developed new symptomatic lesions. The disease was unaffected by antimicrobial therapy. Two of our patients had psoriasis and all were rheumatoid factor-, antinu-clear factor- and HLA-B27-negative. We speculate that chronic recurrent osteomyelitis is a noninfectious inflammatory condition, a seronegative spondyloarthropathy. Chronic recurrent osteomyelitis is a clinical entity that should be recognized so that invasive diagnostic procedures and antimicrobial therapy are appropriately used. The patient may be reassured that this is not a malignant condition although there may be exacerbations over many years.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

A retrospective analysis was performed of 109 previously well infants younger than 4 weeks of age with a history of fever who were evaluated for sepsis in an emergency department. The objective was to assess whether infants who were afebrile at the time of evaluation were at similar risk for serious bacterial infection compared with infants with documented fever at the time of evaluation. Of 109 infants evaluated 54 were afebrile and 55 had fever (rectal temperature, >38°C). Serious bacterial infection occurred in 8 (14.5%) infants with documented fever and in none of those who were afebrile at the time of presentation (P= 0.003). An initial complete blood count profile of the two groups showed that nearly all (96%) in the afebrile group had a complete blood count differential ratio ((% of lymphocytes + % of monocytes)(% of polymorphonuclear leukocytes + % band forms)) of >1, whereas the majority (87.5%) of febrile infants with serious infection had a differential ratio of <.The neonate with a history of fever who is afebrile upon presentation should receive a complete evaluation for possible bacterial infection.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

The usefulness of the Widal test in diagnosing childhood typhoid fever in endemic areas was investigated. The test was done on 150 children with other febrile illnesses and 98 bacteriologically proved cases of typhoid fever. Of the 150 children with nontyphoidal fever, only one had an H agglutinin titer of 1:50. Using an H or O agglutinin titer of 1:50 or more as a criterion for diagnosis, a positive Widal test was found in 88% of typhoid fever cases on the first occasion on which the test was done. If the test was repeated at least 94% of the typhoid cases had a significant result. The Widal test is a useful diagnostic test in children in endemic areas, provided interpretation of the test is made against background information relating to agglutinin levels in normal children in the region.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

Infectious complication rates and associated risk factors occurring during peripheral intravenous therapy with Teflon catheters were determined during a prospective study of 286 cannula insertions. Suppurative phlebitis, cannula-related sepsis or suspected sepsis did not occur. Semiquantitative cannula cultures revealed a colonization rate of 10.4% (12 of 115). Coagu-lase-negative nonadherentStaphylococcuswas the most common colonizing organism occurring in 10 of 12 positive catheters. AlphaStreptococcusand adherent coagulase-negativeStaphylococcuscolonized the remaining catheters. Colonization was not related to the rate of phlebitis, extravasation or cannulation time. No patient- or catheter-related factors increased the risk of colonization. In children in a general pediatric ward the risk of catheter colonization and subsequent sepsis should not be used as reasons for routinely removing complication-free peripheral Teflon catheters at 72 hours.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

Forty-six episodes of cerebrospinal fluid shunt infections developed in 32 patients undergoing cerebrospinal fluid shunt operations during a 13-year period (1972 to 1984). The infection rate was 21%/operative procedure and 33%/patient. The shunt infection rate in revisions of infected shunts was 52%, a rate significantly larger than that in revisions of nonin-fected shunts (11%).Eight patients (25%) of the initially infected patients had more than one infectious episode. Predominating pathogens in patients who had shunt revisions included coagulase-negative staphylococci in 8 of 15 episodes (4 patients). Coagulase-negative staphylococci accounted for 28% and coagulase-positive staphylococci for 14% of the initial infectious episodes. Risk factors for development of shunt infection included age younger than 3 years, a previously infected shunt and surgery to revise the infected shunt. Therapy of infected shunts with antibiotics alone or with antibiotics plus an operative shunt revision resulted in similar success rates.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID