摘要:

Extensive animal and human research has progressively modified post‐trauma fluid resuscitation over the past decades and, despite major advances, several related topics continue to generate intense research interest. In particular, the limitations of both conventional crystalloid and colloid solutions have prompted resurgent interest in the use of hyperosmotic fluids for resuscitation of the multiply injured patient in the presence or absence of concomitant head injuries. This review focuses specifically on recent articles that address clinically important problems related to prehospital and emergency centre resuscitation following severe hypovolaemic shock of the multiply injured patient.

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

How should severe uncontrolled hemorrhage be managed at the prehospital stage and in the emergency room? New experimental models which simulate uncontrolled blood loss have been developed to examine the impact of therapeutic strategies. Recent research on mechanisms and mediators is reviewed and clinical trials on current therapeutic concepts are discussed.

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Recent advances in our understanding of the changes in blood as a result of storage, the role of leukocytes in the storage lesion, their clinical significance and minimization by leukocyte depletion are reviewed. The debate about a role for fresh whole blood is rekindled and the immunosuppressive effects of homologous transfusion are also reviewed.

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Recently published animal and human trials compare the efficacy of different crystalloids, colloids and hypertonic formulations for preoperative hemodilution and resuscitation of hemorrhage, intraoperative hypovolemia, head injury, sepsis, burn injury, and multiple trauma.

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

As the burn patient population can easily be stratified by the degree of injury, the study of burns can relay important information regarding the pathophysiology of multiple trauma. The changes in metabolic, respiratory and cardiovascular function following thermal injury, if understood, can result in dramatic changes in morbidity and mortality in intensive care units.

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

The ultimate aim of head injury management is to reduce morbidity and mortality in the fraction of cases with avoidable intra‐ and extracranial secondary complications, such as intracranial hypertension, hypoventilation or circulatory failure. This requires not only competent emergency services at the scene of an accident and safe transportation but also swift admission to a hospital with experience in diagnosis, comprehensive monitoring and care of head‐injured patients.

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID

ISSN:0952-7907    

出版商:OVID    

年代:1992

数据来源: OVID