| 1. |
21st Meeting of the French Hypertension SocietyPalais des Congrès, Paris, 13–14 December 2001Journal of Hypertension2002, Volume 20 |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1-15
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 2. |
Systolic and diastolic blood pressure control in antihypertensive drug trials |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1461-1464
Giuseppe Mancia,
Guido Grassi,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 3. |
Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1465-1468
Morag Young,
John Funder,
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摘要:
For almost 40 years since its discovery in 1953, the mineralocorticoid hormone, aldosterone, was considered to affect blood volume, and thus blood pressure, by its action to retain sodium at epithelial tissues. Over the past decade, direct effects of aldosterone on the heart and blood vessels, and on the cerebral control of blood pressure, have been established in experimental animals. Simultaneously, the incidence of primary aldosteronism in essential hypertension is now acknowledged to be 10–20%, rather than ⩽ 1%, underscoring a previously unrecognized role for aldosterone in hypertension. The 30% improvement in mortality (and 35% in morbidity) seen in the RALES trial with the addition of low-dose spironolactone to best practice therapy in moderate to severe heart failure, similarly points to an unrecognized role for aldosterone in the pathophysiology of heart failure. Currently, both experimental and clinical studies are directed towards establishing the mechanisms involved in these pathophysiological effects of aldosterone in the cardiovascular system, and of the role of mineralocorticoid receptor antagonists in offsetting or blocking such effects. A brief account of the current state of these mechanisms in at a cellular and tissue level forms the basis of this review.
ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 4. |
Is non-dipping status a predictor of cardiac morbidity? |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1469-1471
Trefor Morgan,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 5. |
Blood pressure response during exercise as a prognostic factor |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1473-1475
Per Lund-Johansen,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 6. |
Genotype interactions and intima-media thickness |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1477-1478
Stéphane Laurent,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 7. |
Endothelial dysfunction in hypertension: fact or fantasy? |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1479-1481
Damiano Rizzoni,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 8. |
Advanced glycation end-products as a potential target for treatment of cardiovascular disease |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1483-1485
Paolo Silacci,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 9. |
Leptin, sympathetic and baroreflex function: another step on the road to sympathetic differentiation |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1487-1489
Guido Grassi,
Mikael Elam,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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| 10. |
Gender differences with antihypertensive drug treatment |
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Journal of Hypertension,
Volume 20,
Issue 8,
2002,
Page 1491-1492
Henry Elliott,
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ISSN:0263-6352
出版商:OVID
年代:2002
数据来源: OVID
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