摘要:

Reduction of large artery distensibility has several adverse consequences for the cardiovascular system. This paper reviews the evidence obtained by measuring distensibility through quantification of changes in arterial diameter versus blood pressure changes at large elastic and middle size muscle artery sites. Evidence is available that arterial distensibility is reduced in conditions as varied as hypercholesterolemia, hypertension, diabetes and congestive heart failure. In some conditions (e.g. hypertension) the alterations are not uniformly distributed in arteries of different structure and size whereas in others (e.g. diabetes and heart failure) they are widespread. In diabetes evidence is available that distensibility changes occur early in the course of the disease. Evidence is also available that in all above conditions treatment can improve arterial distensibility thereby reversing the initial abnormality. This appears to be due to a variable combination of structural and functional factors. Technical ability to determine their precise role in distensibility changes in humans is limited, however.

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

摘要:

Ambulatory blood pressure monitoring (ABPM) can be considered a major achievement in clinical medicine. However, its superiority over traditional clinical measurement has often been overemphasized in the literature. In both cross-sectional and longitudinal studies, ABPM has been compared with clinical blood pressure calculated from only a few readings taken over a short period of time. For reasons of costs and practicality, ABPM should not be considered as a routine test in the assessment of the hypertensive patient. Most patients with borderline hypertension or isolated clinical hypertension can be profitably assessed with multiple clinical readings and self-blood pressure monitoring. Patients with large short-term or long-term blood pressure oscillations appear as optimal candidates to ABPM. The many methodological problems associated with the use of this technique suggest that ABPM is performed only by experienced doctors.

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID

ISSN:0263-6352    

出版商:OVID    

年代:2002

数据来源: OVID