ISSN:0001-6357    

DOI:10.3109/00016358109162278

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

Two types of normal keratinized mucosa were transplanted to subcutaneous sites of nude mice of two different strains. 24 intact specimens of clinically normal human palatal mucosa were transplanted to nude mice of the strain nu/nu NC. The transplants were recovered after 42 d with a recovery rate of 96 %. Moreover, 22 intact specimens of normal rat forestomach mucosa were transplanted to nude mice of the strain nu/nu BALB/c/BOM. These transplants were recovered after 21 d with a recovery rate of 63 %. The histologic features of the transplants were essentially the same as those of the original tissues. However, epithelial outgrowths from the transplants differed with respect to the pattern of keratinization. The outgrowths of human palatal mucosa transplants were essentially unkeratinized, while the outgrowths of the rat forestomach transplants showed continued keratinization.

ISSN:0001-6357    

DOI:10.3109/00016358109162279

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

β-lumicolchicine, an isomer of colchicine which does not interrupt microtubular function, was given to 8 rats in a dose of 1.5 mg/kg. Four rats served as controls. Histomorphological investigations of odontoblasts and dentin in the maxillary incisors after two weeks revealed no disturbances. This finding, compared with the previously reported effects of colchicine, as well as colcemid, vincristine and vinblastine, indicates dentin production to be dependant on microtubules.

ISSN:0001-6357    

DOI:10.3109/00016358109162280

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

A prevalence of 0.11 % of focal epithelial hyperplasia (FEH) was found among 20, 333 adult Swedes. There was no sex difference, the lesion was most prevalent in age groups above 45 years and the lesion was most frequent on the tongue. The frequency of FEH in 15, 132 consecutive routine biopsies was 0.26 %. Four FEH-cells were ultracstruturally examined. They exhibited a clear cytoplasm with scattered ribosomes, a peripheral condensation of tonofilaments, a central aggregation of chromatin clumps with loss of nuclear membrane and an accumulation of desmosome fragments. No viral particles could be identified in these FEH-cells.

ISSN:0001-6357    

DOI:10.3109/00016358109162281

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

In a long-term follow-up of 52 patients with oral lesions of discoid lupus erythematosus (DLE) 8 patients showed a gradual transition of the typical DLE lesions to lesions which closely resemble leukoplakia. Histopathologically and immunopathologically the leukoplakia-like lesions generally snowed features similar to those in leukoplakias not preceded by DLE. Ultrastructurally, the leukoplakia-like lesions showed the presence of cytoplasmic tubular structures in vascular endothelium rn two out of three patients examined. The leukoplakia-like stage is considered to be an inactive or scar-like stage, which may be the mucous membrane counterpart of the atrophic scars following DLE lesions of the skin.A primary examination of a DLE patient presenting oral lesions at the leukoplakia-like stage may result in an incorrect diagnosis. Therefore, when investigating patients with leukoplakias, they should be questioned on previous or present skin lesions as well as symptoms of systemic lupus erythematosus.

ISSN:0001-6357    

DOI:10.3109/00016358109162282

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

Allogenic demineralized dentin implanted in the abdominal wall of quinea pigs induced heterotopic osteoid and bone formation. Samples of this tissue were frozen at–140°C, freeze-dried at -80°C, infiltrated with Spurr®epoxy resin and polymerized. The sections were then studied in the scanning transmission electron microscope, and analytical studies were performed by means of energy dispersive microanalysis.Osteoblasts and young osteoid osteocytes contained more calcium than undifferentiated cells and mature osteocytes. The Ca/P ratio in the cytoplasm of these young matrixproducing cells was high. Phosphorus was found in the nuclei of all cells and to a lesser extent also in the cytoplasm of cells rich in calcium. The initial extra-cellular mineral accumulation also showed a high Ca/P ratio. Small electrondense areas in these regions exhibited an amount of calcium and a Ca/P ratio resembling those of mature mineralized bone. The intial event of the mineralization process seemed to be an accumulation of calcium first in the young matrix-producing cells and then in the surrounding osteoid matrix.The results suggested that the matrix-producing cells are actively involved in the accumulation of calcium and phosphorus both intra- and extra-cellularly.

ISSN:0001-6357    

DOI:10.3109/00016358109162283

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

16 cases of calcifying odontogenic cysts (C.O.C.) were studied and reevaluated. It could be concluded, that the group contained two entities, a cyst and a neoplasm. The cyst occurs as three variants. 1. A simple unilocular cyst with moderate mural proliferations of epithelium and no, or sparse amounts of, dentinoid (dysplastic dentin); it seems to occur during man's entire life span. 2. A unilocular cyst which produces compound or complex odontomes in its luminal part, more rarely it may instead produce an intramurally growing ameloblastic fibroma, which may call for more radical surgery. It occurs mainly in patients between 10 and 29 years of age. 3. A unilocular cyst with extensive luminal as well as mural ameloblastomalike proliferations of epithelium. The C.O.C. may be located outside or inside the bone according to the location of the source of odontogenic epithelium, from which it develops.The neoplasm shows an entirely different structure. It consists of ameloblastoma-like strands and islands of odontogenic epithelium growing infiltratively in a mature connective tissue. Varying amounts of ghost cells are seen in the epithelium and varying amounts of dentinoid is formed in contact with the odontogenic epithelium. The term«Dentinogenic ghost cell tumour»is suggested for this lesion. It is possible that it occurs predominantly in the later part of life. It occurs as an extraosseous as well as an intraosseous lesion. Recurrence has been observed following cystectomy.

ISSN:0001-6357    

DOI:10.3109/00016358109162284

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

The aim of this review has been to suggest that future fluoride preventive programs should be based on what is at present known about the possible cariostatic mechanisms of fluoride. The relative role of enamel fluoride in caries prevention has become increasingly questioned during the last two decades. No significant relationship has been demonstrated between caries experience of the individual and fluoride content of the enamel. Furthermore, the fluoride content in surface enamel between teeth developed in low and«optimal»fluoride areas is too small to explain any significant effect on dissolution rate of the enamel. As the major explanation for the cariostatic effect of fluoride must therefore be sought in its local effect on the oral environment, the possible effects on plaque colonization, composition and metabolic activities are discussed. The effect of even low concentrations of fluoride in the liquid phase on enamel dissolution is described, and it is concluded that the major cariostatic effect of water fluoridation, fluoride tooth paste and mouth rinses can probably be ascribed to regular increases in fluoride ion activity in the oral fluids. The effect of high concentrations of topical fluoride solutions is thought to be a result of a slow dissolution of calcium fluoride deposited in initial caries lesions, whereby an increased fluoride ion concentration is maintained locally for longer periods of time. Finally, the clinical consequences of these considerations are described.

ISSN:0001-6357    

DOI:10.3109/00016358109162285

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor

摘要:

The effect of cleansing the root surface of extracted teeth in either saliva or tap water prior to replantation was studied in green Vervet monkeys (Cercopithecus aethiops). Maxillary central- and mandibular lateral incisors and mandibular first molars were extracted. The extra-alveolar period before replantation was 10 sec. During this period the root surface was cleaned with either saliva or tap water. The replanted teeth were examined histologically after 8 weeks. The histometric analysis showed significantly more normal periodontium and significantly less inflammatory root resorption in teeth cleaned in tap water than in teeth cleaned in saliva. The beneficial effect of this rinsing procedure in clinical practice in case of mature teeth is dubious, as inflammatory resorption is normally controlled by pulp extirpation and a root canal filling. Furthermore, the abovementioned finding is based on the use of tap water with only a moderate chlorine concentration, leading one to suspect that tap water with higher chlorine concentrations may be detrimental to healing. Provisional guidelines for the immediate treatment of avulsed teeth are suggested.

ISSN:0001-6357    

DOI:10.3109/00016358109162286

出版商:Taylor&Francis    

年代:1981

数据来源: Taylor