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1. |
The use of metallocenic esters of n‐hydroxysuccinimide for metallohapten synthesis |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 143-149
I Lavastre,
J Besançon,
P Brossiert,
C Moise,
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摘要:
AbstractDifferent organometallic markers have been described in a new technique for the labelling of many drugs. Thus metallocenic esters of[M = (;CO)3CrC6H5; (;CO)3CrC6H5(;CH2)3; η‐C5H5FeC5H4; (;CO)3MnηC5H4; (;CO)3MnηC5H4COCH2CH2; ηC5H4(;ηC5H5)Co+PF−6] react with primary or secondary amine drugs [DRUGNHR]for a psychostimulant drug: amphetamine; tricyclic antidepressants—desipramine and nortriptyline; a vasodilator—histamine; an adrenergic substance—norfenefrine; and for a central stimulant—meth‐amphetamine, to give the metallohaptens MCON(;R)—DRUG. All these compounds have been fully characterized by different analytical methods and have potentialities for biological assays. This synthetic route was found better than one presented previously which utilized the metallocenic acid chloride MCOCI as intermediate, and could be proposed as a general synthetic route for labelling biological
ISSN:0268-2605
DOI:10.1002/aoc.590050302
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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2. |
Determination of butyltin species by GC/atomic emission spectroscopy |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 151-157
B F Scott,
Y K Chau,
A Rais‐Firouz,
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摘要:
AbstractA commercially available atomic emission detector coupled to a capillary column‐containing gas chromatograph (;GC/AE) was utilized to detect organotin compounds. The response for tin was found to be dependent on the flow rate of the make‐up gas. At flow rates of 174 cm3min−1, 6 × 10−12g of tin could be detected. Lower flow rates decreased the sensitivity. Response curves for two different pressures were established and both plots exhibited curvature at low concentrations. Extracted fish and sediment samples were analysed on the GC/AE system. The technique is element‐specific. The presence of tin compounds could be confirmed by examining the emission spectra taken at the retention time o
ISSN:0268-2605
DOI:10.1002/aoc.590050303
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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3. |
A thermal analytical study of some mono‐ and di‐organotin oxides and carboxylates |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 159-165
S J Blunden,
R Hill,
S E Sutton,
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摘要:
AbstractSimultaneous thermogravimetry and differential thermal analysis studies on a variety of mono‐ and di‐organotin oxides and carboxylates were performed; for the carboxylates, these studies followed119Sn NMR spectroscopic investigation. All the organotin compounds thermally degrade to tin (;IV) oxide (;SnO2) in either air or oxygen, as was confirmed by Mössbauer spectroscopy in the cases of RSn(;O)OH (;R=butyl, octyl) and Bu2SnO.The organotins are less stable than previously believed since evidence for degradation was obtained in many cases at approximately 160–170 °C.In addition it was found that oxygen influences the thermal stability of the organotins, since Bu2SnO did not degrade when heated for 1 h at 280 °C under nitrogen, yet readily broke down at 170°C in air. Furthermore, pure oxygen had the effect of lowering reaction temperatures by approximately 10–12°C compared with
ISSN:0268-2605
DOI:10.1002/aoc.590050304
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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4. |
Catalytic ethylation of alkylbenzenes at high pressure |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 167-172
L Assadourian,
G Gau,
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摘要:
AbstractStudy of the catalytic ethylation ofp‐t‐butyltoluene in the presence of organosodium compounds, and of toluene in the presence of organopotassium compounds, was carried out at an ethylene pressure of 40 bar.Various yields of different products were obtained after 23 h of reaction in the presence of different tertiary polyamines used to complex and solubilize the organoalkali compounds.A higher initial ethylation rate was observed in the presence of organosodium than in the presence of organopotassium species. However, the thermal stability of organopotassium species being higher, much higher yields were observed in their presence in catalytic ethylation reactions than those observed previously.The results obtained concerning metallation or ethylation of hindered alkylaromatics may be interpreted by an anionic mechanism and the activation by a steric eff
ISSN:0268-2605
DOI:10.1002/aoc.590050305
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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5. |
Speciation for analysis of organotin compounds by GC AA and GC MS after ethylation by sodium tetraethylborate |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 173-181
J R Ashby,
P J Craig,
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摘要:
AbstractA range of organotin compounds has been ethylated using the reagent sodium tetraethylborate in a simple one‐step procedure. Analysis of the volatile, fully alkylated derivatives has been achieved by GC AA with confirmation of the identity of the resulting ethylated derivatives by GC MS. Conditions for the GC AA and GC MS analysis of the organometallic ethyl derivatives are give
ISSN:0268-2605
DOI:10.1002/aoc.590050306
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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6. |
Synthesis, characterization andin vitroantitumour properties of complexes of bis(alkoxycarbonylmethyl)tin dibromides with bidentate nitrogen ligands |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 183-190
Zhengquan Zhang,
Huade Pan,
Chun Hu,
Fangxin Fu,
Yunhong Sun,
Rudolph Willem,
Marcel Gielent,
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摘要:
AbstractThe synthesis and characterization of 10 new bis(;alkoxycarbonylmethyl)tin dibromides and of 14 of their complexes with bidentate nitrogen ligands (;bipyridyl, 1,10‐phenanthroline and 5‐nitro‐1, 10‐phenanthroline) are described. Their proton NMR spectra are discussed. Theirin vitroantitumour activity against two human cancer cell lines, MCF‐7 and WiDr, is low compared to antitumour drugs used c
ISSN:0268-2605
DOI:10.1002/aoc.590050307
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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7. |
Active sites, nature and mechanism of carbon dioxide—propylene oxide copolymerization and cyclization reactions employing organozinc—oxygen catalysts |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 191-194
Witold Kuran,
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摘要:
AbstractReaction of carbon dioxide with propylene oxide in the presence of catalysts with condensed zinc species (;derived from diethylzinc and dihydric phenols, e.g. catecholo C6H4(;OH)2and saligenin0 HOC6H4CH2OH) yields poly(;propylene carbonate) as well as propylene carbonate. The above reaction in the presence of catalysts with noncondensed zinc species (;derived from diethylzinc and phenol) yields propylene carbonate as the main product, but in relatively low yield. The mechanism of the linear and cyclic carbonate formation is discussed in terms of the nature of the catalyst's active sites for both ty
ISSN:0268-2605
DOI:10.1002/aoc.590050308
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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8. |
Synthesis, characterization andin vitroantitumour activity of di‐n‐butyltin(;iv) derivatives of some aromatic carboxylic acids, including aspirin |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 195-201
Abdelkader Meriem,
Rudolph Willem,
Monique Biesemans,
Bernard Mahieu,
Dick de Vos,
Peter Lelieveld,
Marcel Gielen,
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摘要:
AbstractEleven di‐n‐butyltin(;IV) derivatives of the type (;a) (;C4H9)2(;XYC6H3COO)2Sn or (;b) {[(;C4H9)2(;XYC6‐H3COO)Sn]2O}2(;X, Y = H, 2‐OH, compound 1a; H, 2‐OCH3, compounds 2a and 2b; H, 2‐OCOCH3, 3a; 2‐OH, 3‐OCH3, 4a; 2‐OH, 3‐CH3, 5a; H, 3‐OCH3, 6a and 6b; H, 3‐N(;CH3)2, 7a; H, 2‐(;CF3), 5‐(;CF3), 8a and 3‐OCH3, 4‐OH, 9a) have been prepared and characterized by1H,13C and119Sn NMR, Mössbauer and mass spectroscopy. Thein vitroantitumour activity of these compounds against MCF‐7 human tumour cells was higher than that ofcis‐platin, but only three compounds, 4a, 8a and 9a, scored better thanc
ISSN:0268-2605
DOI:10.1002/aoc.590050309
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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9. |
X‐Ray photoelectron spectroscopy and electrical conductivity studies of metallophthalocyanine sheet polymers |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page 203-206
Hari Singh Nalwa,
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摘要:
AbstractThe X‐ray photoelectron spectroscopy (XPS) technique has been used to characterize metallophthalocyanine sheet polymers having peripheral carboxyl groups. A comparative analysis of the XPS and electrical conductivity data of metal‐free, and nickel‐ and copper‐containing, phthalocyanine sheet polymers has been described. Metallophthalocyanine sheet polymers exhibited a maximum conductivity of about 1 S cm−1on
ISSN:0268-2605
DOI:10.1002/aoc.590050310
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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10. |
Masthead |
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Applied Organometallic Chemistry,
Volume 5,
Issue 3,
1991,
Page -
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ISSN:0268-2605
DOI:10.1002/aoc.590050301
出版商:John Wiley&Sons, Ltd.
年代:1991
数据来源: WILEY
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