摘要:

2 cases of acute idiopathic thrombotic thrombocytopenic purpura are reported. Both of them were treated with plasma exchange, antiplatelet drugs and prednisolone and both completely recovered. Plasma exchange appeared to be the critical treatment. In 1 of these cases the prostacyclinlike activity released from venous tissues and the ability of plasma to stimulate synthesis of prostacyclinlike activity from venous tissues exhausted after repeated washings were investigated. Both activities were detectable and comparable to those of a healthy control. These findings do not support the hypothesis of a major role played by the prostacyclin system in the pathogenesis of trombotic thrombocytopenic purpura.

ISSN:0001-5792    

DOI:10.1159/000207056

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A 16-year-old female developed a hemolytic uremic syndrome 9 months after undergoing bone marrow transplantation for acute lymphoblastic leukemia during second relapse. There appears to be no etiologic relationship between the post-transplant immune status and the hemolytic uremic syndrome. The patient succumbed later to recurrent leukemia.

ISSN:0001-5792    

DOI:10.1159/000207057

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Spontaneous complete remission of 2 months’ duration was observed in a 34-year-old man with acute myeloid (monocytic) leukaemia. In vitro culture of granulocyte-monocyte colony-forming units showed normal growth during remission but in relapse the growth pattern was grossly abnormal and typical of acute myeloid leukaemi

ISSN:0001-5792    

DOI:10.1159/000207058

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A 22-year-old patient diagnosed as having Fanconi’s plastic anemia turning to acute erythroleukemia is described. The diagnosis was based on congenital malformations, pancytopenia and the known chromosomal abnormalities. We call attention to the patient’s age at time of diagnosis, the turn into erythroleukemia, the cataracts and the giant marker chromosome in bone marrow cells – features that make this patient except

ISSN:0001-5792    

DOI:10.1159/000207059

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

We have determined the incidence of circulating anticoagulants in a group of 400 healthy subjects. We have detected two factor VIII inhibitors and one circulating anticoagulant against prothrombinase, with a total incidence of 0.75%. The presence of these inhibitors was not accompanied by hemorrhagic manifestations.

ISSN:0001-5792    

DOI:10.1159/000207060

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

2 patients with rheumatoid pleuropulmonary complications are described. The levels of immune complexes within the inflamed target organ were much higher than in the serum. This observation strongly implies the local production of these complexes.

ISSN:0001-5792    

DOI:10.1159/000207061

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Because patients with diabetes mellitus are at increased risk for vascular disease, we suspected that they might have increased circulating platelet aggregates. Therefore, we determined the platelet aggregate ratio of 30 diabetic patients (15 diagnosed before 30 years of age and classified as juvenile-onset and 15 diagnosed after 30 years of age and classified as adult-onset) and 301 controls. The mean platelet aggregate ratio of the juvenile-onset diabetics was 0.75 and of their controls was 0.91 (p < 0.02) confirming our hypothesis in this subgroup. However, the mean platelet aggregate ratio of the adult-onset diabetics was not lower than that of their controls.

ISSN:0001-5792    

DOI:10.1159/000207062

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Hyperthyroidism is described in a 20-year-old man treated 8 months before by radiotherapy (mantlefield irradiation) for Hodgkin’s disease. In contrast to hypothyroid dysfunction, hyperfunction of the thyroid gland is unusual after mantlefield irradiation. A possible relationship is discusse

ISSN:0001-5792    

DOI:10.1159/000207063

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0001-5792    

DOI:10.1159/000207064

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0001-5792    

DOI:10.1159/000207065

出版商:S. Karger AG    

年代:1982

数据来源: Karger