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1. |
Treatment of Multiple Myeloma |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 237-240
Raymond Alexanian,
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ISSN:0001-5792
DOI:10.1159/000207408
出版商:S. Karger AG
年代:1980
数据来源: Karger
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2. |
Benign Bence Jones Gammopathy |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 241-246
Giorgio Paladini,
Pietro G. Sala,
Pieiro A. Santini,
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摘要:
A case of isolated λ-light chain proteinemia and proteinuria is reported. During a 42-month follow-up, no sign of myelomatosis or amyloidosis developed and Bence Jones proteinuria remained nearly of the same magnitude. This case of apparently idiopathic Bence Jones gammopathy, the first of λ-type so far reported, is added to similar observations to give further support to the contention that a benign counterparty to light-chain myeloma may exis
ISSN:0001-5792
DOI:10.1159/000207409
出版商:S. Karger AG
年代:1980
数据来源: Karger
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3. |
Fcγand FcμReceptors in B Cell Neoplasms |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 247-251
Toshio Hattori,
Takashi Uchiyama,
Kiyoshi Takatsuki,
Haruto Uchino,
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摘要:
Membrane receptors for the Fc portions of IgG (Fcγ receptor) and IgM (Fcμ receptor) on leukemic cells in B cell neoplasms in various developmental stages were studied. In 6 out of 7 patients with B-CLL, leukemic cells had both receptors. In macroglobulinemia, leukemic cells had one or the other of Fcγand Fcμ receptors. In plasma cell leukemia and plasmacytoma, malignant cells had neither Fcγ nor Fcμ receptors. The disappearance of Fc receptors appears to be associated with B cell differenti
ISSN:0001-5792
DOI:10.1159/000207410
出版商:S. Karger AG
年代:1980
数据来源: Karger
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4. |
Effect of Daily Administration of Cytotoxic Drugs on the Erythroid and Granulocytic Repopulating Ability of Rat Bone Marrow |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 252-256
G.R. Standen,
N.M. Blackett,
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摘要:
The erythroid and granulocytic repopulating ability of rat bone marrow has been measured after daily administration of three alkylating agents: dimethylmyleran, busulphan and cyclophosphamide. Three different patterns of response were observed. The results emphasize the variability of the response of haemopoietic tissue to repeated administration of different cytotoxic drugs and provide further evidence that erythroid and granulocytic repopulating assays measure different populations of precursor cells.
ISSN:0001-5792
DOI:10.1159/000207411
出版商:S. Karger AG
年代:1980
数据来源: Karger
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5. |
Erythropoietic Changes Effected by Foreign Serum in the Mouse |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 257-261
José L. Scaro,
Carmen Miranda,
Beatríz M. Martin,
Marco Carrera,
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摘要:
Injection of foreign serum into mice increases erythrocyte formation as evaluated by ferrokinetics studies. When erythropoiesis is depressed either by fasting or plethora, the wave of erythropoiesis that follows a transient increase of endogenous erythropoietin is clearly enhanced by pretreatment of the recipients with foreign serum. The response includes a restoration of the responsiveness of the spleen of fasted mice to endogenous erythropoietin stimulation. These changes seem related to an effect of foreign serum on the transition of primitive hematopoietic progenitors into erythroid-committed progenitors.
ISSN:0001-5792
DOI:10.1159/000207412
出版商:S. Karger AG
年代:1980
数据来源: Karger
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6. |
Additional Data from Two Kindreds with Genetically Induced Deficiencies of Erythrocyte Pyrimidine Nucleotidase |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 262-267
Donald E. Paglia,
Kay Fink,
William N. Valentine,
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摘要:
Two subjects, not previously reported in detail, had severe inherited deficiencies of erythrocyte pyrimidine nucleotidase. This was manifested hematologically by moderate hemolytic anemia with splenomegaly, morphologically by punctate basophilic stippling of Wright’s stained erythrocytes, and biochemically by intraerythrocytic accumulation of pyrimidine nucleotides, elevated concentrations of reduced glutathione, and partial deficiencies of ribosephosphate pyrophosphokinase. All 5 of their children were asymptomatic and phenotypically normal except for intermediate reductions in activities of pyrimidine nucleotidase consistent with heterozygosity for an autosomal recessive defec
ISSN:0001-5792
DOI:10.1159/000207413
出版商:S. Karger AG
年代:1980
数据来源: Karger
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7. |
Human Haemoglobins and Haemoglobinopathies in Arabia: Hb·Arab in Saudi Arabia |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 268-273
M.A.F. El-Hazmi,
H. Lehmann,
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摘要:
In the Arabian peninsula, haemoglobinopathîes, though very interesting, are still far from being fairly established. With the exception of the eastern province of Saudi Arabia, where several aspects of the sickle-cell disease have been focused upon, few reports have appeared in the literature. However, in 1974 one of us (M. A. F. E. H.) has initiated a comprehensive investigation, in collaboration with the Ministry of Health on haemoglobinopathies in various parts of the country. These studies have revealed a new pocket for the sickle-cell gene and a new structural abnormality. In the present report we describe the first finding of Hb·Arab in Saudi Arabia, which may shed more light on the anthropological significance of this haemoglobin varian
ISSN:0001-5792
DOI:10.1159/000207414
出版商:S. Karger AG
年代:1980
数据来源: Karger
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8. |
Hemoglobin C-I-A |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 274-277
George R. Honig,
Marsha Borders,
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摘要:
Hemoglobin I (α 16 lys →·glu) was identified in association with hemoglobins C and A in a black American woman who had no clinical or hematologic disease. Her erythrocytes contained four major hemoglobins, all of which were separable by DEAE-cellulose column chromatography. Nearly 50% of the total recovered αI-chains were present in combination with βc, suggesting that there may have been preferential formation of the αlβchybrid hem
ISSN:0001-5792
DOI:10.1159/000207415
出版商:S. Karger AG
年代:1980
数据来源: Karger
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9. |
Recurrent Thrombosis in a Patient with Factor XII Deficiency |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 278-282
Jørn Dyerberg,
Erik Stoffersen,
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摘要:
The case history of a patient with moderate factor XII deficiency and recurrent deep vein thrombosis is described. A decreased resting fibrinolytic capacity suggests that ‘in vivo’ Hageman factor acts mainly as a promotor of clot dissolution. It further indicates that the in vitro demonstration of factor XII as an activator for other biochemical pathways might be of minor importance in vivo, as alternative pathways for activation of these systems ex
ISSN:0001-5792
DOI:10.1159/000207416
出版商:S. Karger AG
年代:1980
数据来源: Karger
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10. |
Acute Leukaemia after Prolonged Chlorambucil Treatment for Non-Malignant Disease: Report of a New Case and Literature Survey |
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Acta Haematologica,
Volume 63,
Issue 5,
1980,
Page 283-285
J.P. Aymard,
J. Frustin,
F. Witz,
J.N. Colomb,
P. Lederlin,
R. Herbeuval,
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摘要:
A case of acute myeloblastic leukaemia is reported in a patient treated with chlorambucil during 72 months for multiple sclerosis. In a review of the medical literature, 43 additional reports of acute leukaemia after chlorambucil therapy for non-malignant diseases were found. Most cases are of a non-lymphoid type and preceded by various blood and bone marrow abnormalities. The prognosis is poor with a short survival. The risk of developing acute leukaemia after long-term immunosuppressive treatment with chlorambucil is emphasized.
ISSN:0001-5792
DOI:10.1159/000207417
出版商:S. Karger AG
年代:1980
数据来源: Karger
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