摘要:

The PHA-induced blastogenesis in lymphocyte cultures of acute leukemia patients in remission was investtigated. Lymphocytes of patients untreated for more than 2 weeks showed normal blast transformation. Lymphocytes of patients in treatment with 6-mercaptopurine or methotrexate showed in some cases normal blast transformation and in other cases lack of blastogenesis. It seems that in these patients the lymphocytes are sensible to the iramunodepressive action of the mentioned antimetabolites, whereas in the other patientsthe lymphocytes are resistant to that action

ISSN:0001-5792    

DOI:10.1159/000208647

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

The phagocytic ability and the proliferative activeity of leukaemic blast cells were investigated in 24 patients with actue leukaemia. A certain phagocytic activity was found in most cases of acute leukaemia. The highest phagocytic activity occurred in monocytic leukaemia. Blast cell populations with a relative high phagocytic activity showed a low proliferative activity and only a few cells in DNA synthesis. The blastcells with phagocytosis are more mature cells. We got the impression that they areresting cells and possibly end cells

ISSN:0001-5792    

DOI:10.1159/000208648

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Granulocytes obtained from patients with anoxia and with brain damage showed a consistant impairment of phagocytosis and adhesiveness. This phenomenon was not reversed by the addition of fresh human serum. These observations reveal a relationship between in vivo anoxia and brain damage with granulocyte function.

ISSN:0001-5792    

DOI:10.1159/000208649

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Two patients with a known quinine induced allergic thrombocytopenia have been studied in order to detect in vitro the presence of drug-dependent antibodies in their plasma. The platelet factor 3 and platelet acid phosphatase availability tests have shown that these antibodies are still present several years after the last exposition to quinine followed by the typical clinical symptoms. The demasking of acid phosphatase activity is increased in presence of calcium ions. The possible mechanisms leading to the demasking of PF 3 and acid phosphatase after exposition of the patient’s platelets to quinine are discuss

ISSN:0001-5792    

DOI:10.1159/000208650

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

The percentage of Hb S in hemolysates from 109 Saudi Arab males was found to range from 18–47%, with a mean of 33%, an obvious mode at 32–34% and clear skewing of the overall pattern toward lower values. A tentative explanation of this finding is the concurrence of the α-thalassemia trait in this population, which tends toreduce the percentage of Hb S in erythrocytes of double heterozy

ISSN:0001-5792    

DOI:10.1159/000208651

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

The results of a first investigation on hemoglobins of Maya Indians of the Yucatan Peninsula in Mexico are set out. This investigation confirms the very inferquent occurrence of hemoglobinopathy among the Indians of the American continent

ISSN:0001-5792    

DOI:10.1159/000208652

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0001-5792    

DOI:10.1159/000208653

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0001-5792    

DOI:10.1159/000208654

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0001-5792    

DOI:10.1159/000208655

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:0001-5792    

DOI:10.1159/000208646

出版商:S. Karger AG    

年代:1971

数据来源: Karger