摘要:

Simultaneous isotope dilution curves were recorded from the right upper (QRUZ) and right lower lung zones (QRLZ) by surface scanning in the sitting and recumbent positions in 15 normal high-altitude-born (HAD) males and in 1 HAD female as well as from 3 male newcomers, using 10 µCi of 131I-HSA as a bolus injection into the right ventricle. Similar information was also obtained at sea level from 5 normal males. The mean percent distribution of total pulmonary blood flow (Q) to RUZ and RLZ in the two body postures indicate (1) that in the vertical position RUZ in males receives about 17% of Q regardless of altitude and elevation in mean pulmonary artery pressure (MPAP) in HAD of 8.6 mm Hg above that extant at sea level; (2) recumbency at high altitude showed QRUZ also to be lower than at sea level; (3) elevation in MPAP at altitude has no significant effect on changing the sea-level distribution pattern of pulmonary blood flow

ISSN:0025-7931    

DOI:10.1159/000193649

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Nitrogen dioxide poisoning was experimentally produced in dogs. PO2, PCO2 and pH were measured in poisoned animals and during treatment with hyperbaric oxygen (OHP) lung lesions in both groups were evaluated. It is concluded that OHP has a deleterious effect both in terms of mortality and pathological changes.

ISSN:0025-7931    

DOI:10.1159/000193650

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The authors studied bronchial reactivity in children with cystic fibrosis and with deformative bronchitis. The reaction of the bronchi was studied both by inhalatory and exercise provocation. Inhalatory tests were monitored by means of a whole body plethysmograph. Free-range run was used for the exercise test, and the peak expiratory flow rate was measured. The described technique of inhalatory tests was accurate, safe, and not tiring for the patient. No distinct difference in bronchial reaction between the two groups of patients could be stated. The bronchial reaction to the inhalatory and exercise tests was stronger in both groups than in normals but not as strong as in asthmatics. The nature of bronchial hyperreactivity in those patients is still unknown. The inhalatory test seems to be more sensitive than the exercise test in detecting that hyperreactivity.

ISSN:0025-7931    

DOI:10.1159/000193651

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The authors experimented with a corticosteroid molecule, dexamethasone-isonicotinate, by pressurized aerosol, testing it on 15 subjects suffering from a bronchial obstructive syndrome (7 cases of asthmatic bronchitis, 6 of chronic bronchitis with pulmonary emphysema, 2 of bronchial asthma). In such patients clinical evolution, spirographic patterns, and airway resistance were studied by means of body plethysmograph before and after administration of 0.25 mg dexamethasone-isonicotinate four times a day. In four subjects daily variations of airway resistance before and after 10 days of treatment were evaluated: in three cases the resistance diminished noticeably at all times of the day after therapy. In eleven cases the functional parameters were recorded before and after 7 days therapy, and ten subjects were followed up by a monthly, check during 6 months of therapy. In both methods, the authors obtained good or very good results in more than half of the subjects and fair results in a fifth of the subjects; in the remaining patients poor results were obtained. Side-effects attributed to improper dosage were never observed.

ISSN:0025-7931    

DOI:10.1159/000193652

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The influence of tuberculin administered in aerosol on the ventilatory parameters in patients suffering from chronic bronchitis has been studied. The diameter of the tuberculin skin reaction 1 day after inhalation of tuberculin was found to be related to a decrease in maximal 1-sec forced expiratory volume and maximal midexpiratory flow- rate. Significant decrease in the parameters of dynamic pulmonary ventilation occurred only in a certain proportion (24.6 %) of tuberculin-positive patients suffering from chronic bronchitis of the obstructive type.

ISSN:0025-7931    

DOI:10.1159/000193653

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The pathophysiology of pulmonary hematoma is discussed. The presence of the air-crescent sign in a coin lesion is nonspecific; however, it may direct the attention of the physician to consider a traumatic etiology.

ISSN:0025-7931    

DOI:10.1159/000193654

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0025-7931    

DOI:10.1159/000193655

出版商:S. Karger AG    

年代:1975

数据来源: Karger