ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00172.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractThe possibility was investigated that canine antral circular muscle received a direct innervation from intrinsic motor nerves to initiate electrical slow waves. Thin slices of antral muscle were used for intra‐cellular recordings in vitro. Single electrical shocks evoked slow waves identical to spontaneous slow waves, at all sites across the entire thickness of the circular muscle. Excitation was mediated by non‐cholinergic (atropine‐resistant) excitatory junction potentials that gave rise either to attenuated or to full slow waves, depending on the refractory period of the smooth muscle cells. Short bursts of electrical shocks evoked non‐cholinergic (atropine‐resistant) inhibitory junction potentials which were followed by a rebound slow wave. Prolonged stimulation (at 1 Hz) evoked slow waves at a rate of 3–4 cycles per minute; stimulation at greater frequencies (2–10 Hz) evoked a hyperpolarization that gave way to breakthrough slow waves at a rate of 5–6 cycles per minute. Long periods of hyperpolarization were followed by an ‘off‐response’ involving a burst of slow waves that slowly decreased in frequency. In summary, canine antral circular muscle possesses a complex motor innervation involving excitatory and inhibitory neurostransmitters (of unknown type), similar to the motor innervation of the adjacent pyloric circular muscle and nearby duo

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00173.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractThe aim of the study was to test the hypothesis that excitatory A2and inhibitory A1receptors coexist on myenteric AHIType 2 neurons, and are positively coupled to adenylate cyclase to stimulate cAMP formation. The A2agonists NECA and CGS 21680 increased excitability and depolarized the membrane in 40% of 71 AH/Type 2 neurons. In the remainder, the agonists depressed excitability and hyperpolarized the neurons. In 13% of neurons, A2agonists caused a concentration‐dependent depolarization at nanomolar concentrations, followed by hyperpolarization at higher concentrations. CGS 21680 (EC50=0.15 nM) was 133‐fold more potent than NECA (EC50= 20 nM) in depolarizing AH/Type 2 neurons. The A1agonist, CCPA, caused hyperpolarization and depressed excitability in more than 90% of neurons. The potency profile of agonists for depolarization was CGS 21680 ≫ NECA ≫>CCPA. NECA augmented at nanomolar and inhibited at micromolar concentrations, excitatory depolarizing responses to forskolin in AH/Type 2 neurons; whereas, CCPA only inhibited the action of forskolin. In parallel studies on enzymatically dissociated myenteric ganglia, when the ganglia were exposed to priming concentrations of forskolin (5 μM) in the presence of Ro‐20 1724, NECA enhanced the stimulatory action of forskolin on CAMP formation. This effect was abolished by the adenosine receptor antagonist DPSPX. The potency of NECA for stimulation of adenylate cyclase equalled that for depolarization of the AH/Type 2 neurons. The results suggest that high affinity excitutory A2receptors are coupled to adenylate cyclase in a minority subset of AH/Type 2 myenteric neurons, and that inhibitory A1and excitatory A2receptors are co‐localized on some AH/Ty

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00174.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractSurface vibration analysis is a non‐invasive test of gastrointestinal activity, which shows an ‘obstructive’ pattern of hyperactivity and quiescence, corresponding to cluster contractions, in experimental obstruction. This study has evaluated surface vibration analysis against clinical and operative diagnosis in suspected partial intestinal obstruction. Forty‐six patients and 18 volunteers underwent surface vibration analysis tests. On clinical grounds, 28 patients were considered likely to have partial intestinal obstruction and underwent laparotomy. Only 14 of these were found to have dilated bowel proximal and normal or collapsed bowel distal to a potentially obstructive lesion, such as adhesions. Surface vibration analysis showed an ‘obstructive’ pattern in 12/14 patients with obstruction compared to only 3/14 without operative evidence of any obstruction. Surface vibration analysis amplitude values were also significantly higher in the obstruction group. Surface vibration analysis may provide a useful adjunct in the diagnosis of partial intestinal

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00175.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractColonic perception threshold and pain threshold for distension stimuli were measured in 19 healthy subjects and in 19 long‐standing insulin‐dependent Type I diabetics who had autonomic and peripheral neuropathy and complained of gastrointestinal symptoms. The age range 26–72 years in both groups. Neither perception threshold nor pain threshold was significantly different between patients and controls. Abnormal delay of the primary evoked contraction after stimulus was found in 44% of the patients and abnormal colonic oscillation after stimulus was recorded in 53% of the patients. The colonic wall trended to higher compliance in diabetics. These abnormalities did not correlate with perception or pain threshold, suggesting that the sensory afferent and motor efferent systems work relatively independently. Also, the abnormalities did not correlate with the type of gastrointestinal symptom, metabolic state or half‐time gastric emptying. Results suggest a substantial integrity of the colonic afferent system, a local derangement of the colonic wall with an impairment of the enteric system and a probable derangement of efferent p

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00176.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractConventional flux chamber and intracellular recording methods were used to investigate the effect of prostaglandin E2on ion transport and on electrical behaviour of submucosal neurones in guinea‐pig colon. In flux chamber experiments, prostaglandin E2evoked a dose‐dependent increase in short‐circuit current. The response was reduced by serosal addition of bumetanide, tetrodotoxin or atropine, but not hexamethonium or piroxicam. This indicates that the response to prostaglandin E2was mediated in part by activation of chloride secretion via submucosal neurons. Application of prostaglandin E2to submucosal neurones evoked a depolarization of the membrane potential associated with an enhanced spike discharge which was frequently triggered by fEPSPs. The depolarizing response to prostaglandin E2was not affected by tetrodotoxin, indicative of a direct effect of prostaglandin E2on the impaled neurones. However, the increased spike activity was synaptically driven suggesting an additional activation of other cells. Prostaglandin E2had no excitatory or inhibitory effect on cholinergic fast excitatory postsynaptic potentials. The study suggests that prostaglandin E2may function as a neuromodulator to evoke nerve‐mediated chloride secretion through activation of submucosal neurones. The results further indicate that prostaglandin E2may influence mucosal function by altering electrical behaviour of submucosal neurones leading to spread of excitation throughout the

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00177.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractMyenteric ganglia dissociated from the small intestine of adult guinea‐pigs survived in long‐term culture (1–2 months) and progressed to structural organization resembling the myenteric plexus in situ. Developmental changes were similar to cultures derived from neonatal intestine. After one week, the neurons gathered into clusters on a glial cell carpet. Processes from the neurons branched and ramified over the glial substrate. As the cultures matured, the processes joined into tracts and the neurons and glia formed compact aggregates reminiscent of ganglia interconnected by fibre bundles. Injection of dye revealed characteristic Dogiel I and II neuronal morphology. Electrical recording identified electrical and synaptic behaviour comparable to intact myenteric plexus, longitudinal muscle preparations, except slow synaptic excitation was absent. Pharmacological responses to forskolin and 5‐hydroxytryptamine were essentially the same as in freshly dissected preparations. Lucifer yellow injected into single glial cells spread to a broad population indicative of the dye coupling found among glia in the myenteric plexus in situ. The results suggest that adult myenteric ganglia in culture are a useful model for investigation of aspects of enteric neurobiology including: (a) formation of connections in microcircuits; (b) cellular neurophysiology of enteric neurons; (c) neuropharmacology; and (4) cell biology of neuronal‐glial interactions in the myenter

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00178.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

AbstractNeurokinins have been implicated as excitatory neuromessengers involved in the mediation of different reflexes in the mammalian gastrointestinal tract. However, marked interspecies variations in reported receptor distribution and in regional peptide content do not allow the extrapolation of results obtained in animals to the human gastrointestinal tract. To characterize the myogenic and neurogenic mechanical response of human colonic muscle to neurokinins, we studied the inotropic response of muscle strips from the proximal and distal human colon, and the rectum to the NK‐1 receptor agonists substance P (SP) and substance P methylester (SPME), to the NK‐2 receptor agonists neurokinin A (NKA) and neurokinin A 4–10 (NKA4–10) and to the NK‐3 receptor agonist neurokinin B (NKB). Even though all neurokinins caused a dose‐dependent inotropic response, NKA was 15–20 times more potent than SP or SPME in all areas of the colon. The efficacy and potency of NKA was highest in distal circular colon. The response to exogenous SP and NKA was partially mediated by actions of these peptides on myenteric nerves, as indicated by the sensitivity of the mechanical response to atropine, tetrodotoxin and hexamethonium. Densensitization to NKA, but not to SP significantly increased the atropine‐resistant part of the off response to electrical field simulation. These results suggest the following: (a) NKA is a potent agonist in human colon with a proximal to distal gradient in potency and in efficacy; (b) the response to NK‐I, NK‐2 and NK‐3 agonists involves cholinergic and nicotinic mechanisms; (c) the increase in the atropine resistant off‐response after desensitization with NKA is consistent with the existence of inhibitory NK‐2 receptors on non‐ch

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00179.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00180.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY

摘要:

OESOPHAGEAL PERCEPTION BUT NOT MOTOR FUNCTION IS DECREASED BY INTRALUMINAL BENZOCAINEAbnormal motor response to graded esophageal DISTENSION IN NON‐CARDIAC CHEST PAIN ‐ THE MISSING LINK?LOCALISATION OF CORTICAL CENTRES FOR HUMAN OESOPHAGEAL FUNCTION BY COREGISTRATION OF MAGNETOMETRY AND MAGNETIC STIMULATION DATA ON MAGNETIC RESONANCE SCANSDIFFERENT AMOUNTS OF INTRADUODENAL LIPID ALTER GASTRIC, SENSORY BUT NOT THE MOTOR RESPONSES TO DISTENSIONACUPUNCTURE AFFECTS PERCEPTION OF GASTRIC DISTENSION BY NALOXONE‐SENSITIVE PATHWAYS IN HEALTHY VOLUNTEERSA POSSIBLE EXPLANATION OF THE PROKINETIC PROPERTIES OF 5‐HT3 ANTAGONISTS.SENSITIVITY OF MESENTERIC AFFERENT NERVES TO NITRIC OXIDEANTINOCICEPTIVE EFFECTS OF CINITAPRIDE IN TWO MODELS RELATED TO VISCERAL PAIN IN RODENTS.SUBSTANCE P STIMULATES AND INHIBITS INTESTINAL PERISTALSIS BY AN ACTION ON DISTINCT RECEPTORS.INVESTIGATION OF THE MECHANISM OF NITRIC OXIDE‐INDUCED CONTRACTION IN THE RAT SMALL INTESTINEINTESTINAL MOTILITY RESPONSES TO NEUROPEPTIDE γIN VITROANDIN VIVOIN THE RAT; COMPARISON WITH NEUROKININ 1 AND NEUROKININ 2 RECEPTOR AGONISTS.NITRERGIC SYMPATHETIC RELAXATION OF THE GUINEA‐PIG STOMACH IS INCREASED BY BLOCKADE OF α2ADRENORECEPTORS.GUT MOTILITY DISORDERS IN CALVES SENSITIVE TO SOYA WHEN FED CHRONICALLY.SMALL BOWEL ALLOGRAFT PARALYSIS OCCURS DURING EARLY‐STAGE ACUTE REJECTION IN A RAT MODEL.SPIKE ACTIVITY AND THE MIGRATING MOTOR COMPLEX OF THE SMALL BOWEL IN THE SENSITIZED RAT IS SELECTIVELY VULNERABLE TO STRESS.FEDOTOZINE INHIBITS ABDOMINAL CONSTRICTIONS INDUCED BY COLONIC DISTENSION DURING COLONIC IRRITATION IN CONSCIOUS RATSMORPHOLOGY AND NEUROCHEMICAL CODING OF FUNCTIONAL DISTINCT ENTERIC NEURONES.PERIPHERAL CCK‐B RECEPTORS AND CENTRAL CCK‐A RECEPTORS MODULATE SMALL INTESTINE MOTOR PATTERNS IN THE RATA UNIQUE SPEED CONTROL SYSTEM FOR THE EXTERNAL ANAL SPHlNCTER.INTESTINAL PHASE OF HUMAN ANTRO‐PYLORO‐DUODENAL MOTILITY: CHOLlNERGlC AND CCK‐MEDIATED REGULATION.L‐NITROARGININE (NOARG) BLOCKS THE RELAXATION OF THE RAT DUODENUM INDUCED BY THE ACTIVATION OF CHOLECYSTOKININ (CCK) RECEPTORS.ROLE OF NITRIC OXIDE (NO) IN THE REGULATION OF THE SMALL INTESTINE MOTOR PATTERNS.NO MEDIATES GASTRIC RELAXATION INDUCED BY VAGAL STIMULATION IN THE ANESTHETIZED DOG.CHOLINERGIC MEDIATION OF ERYTHROMYCIN STIMULATING GASTRIC MOTILITY AND PANCREATIC SECRETION IN HUMANS.THE EFFECTS OF LONG‐TERM TREATMENT WITH ANTHRANOIDS ANDSODIUM PICOSULPHATE ON THE CONTENTS OF VASOACTIVE INTESTINAL POLYPEPTIDE, SOMATOSTATIN, AND SUBSTANCE P IN RAT COLONS.OPTICAL RECORDING OF MEMBRANE POTENTIAL CHANGES IN CULTURED MYENTERIC NEURONS USING A LASER CONFOCAL MICROSCOPE.NPY MICROINJECTED INTO THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS (PVN) STIMULATES COLONIC TRANSIT WITHOUT AFFECTING GASTRIC EMPTYING TN THE CONSCIOUS RAT.THE NITRERGIC FACTOR RELEASED FROM NON‐ADRENERGIC NON‐CHOLINERGIC NERVES PHARMACOLOGICALLY BEHAVES LIKE NITRIC OXIDE.DISTRIBUTION OF VIP‐ AND NITRIC OXIDE SYNTHASE‐IMMUNOREACTIVE NEURONS IN THE ENTERIC PLEXUS OF THE HUMAN COLON.CO‐TRANSMITTERS PRESENT IN CHOLINERGIC ENTERIC NEURONES OF THE GUINEA‐PIG STOMACH.BOMBESIN, SOMATOSTATIN AND VIP RELEASE BY cAMP‐AND cGMP‐DEPENDENT MECHANISMS FROM ENTERIC SYNAPTOSOMESINVOLVEMENT OF K+‐CHANNELS AND INTRACELLULAR CA2+‐STORES IN THE INHIBITORY ACTION OF NANC MEDIATORS IN RAT ILEUMAUTONOMIC FUNCTION DISORDERS IN PATIENTS WITH ACHALASIA OF THE ESOPHAGUS.OESOPHAGEAL MOTILITY AND GASTROOESOPHAGEAL REFLUX IN PATIENTS WITH VARIANT ANGINA PECTORIS.UPPER ESOPHAGEAL SPHINCTER BEHAVIOUR FOLLOWING MAGNETOELECTRICAL STIMULATION OF THE HUMAN CORTEX.CORRELATION BETWEEN GASTRIC AND GALLBLADDER EMPTYING AND FILLING IN NORMAL SUBJECTS AND PATIENTS WITH IDIOPATHIC DYSPEPSIA.CHRONIC INTESTINAL PSEUDO‐OBSTRUCTION: ANTI‐DUODENAL MANOMETRY MAY PREDICT OUTCOMEPROGRESSIVE MUSCLE RELAXATION (PMR) REDUCES SYMPTOMS AND INCREASES THE THRESHOLD OF COLONIC PAIN PERCEPTION WITHOUT MODIFYING COLONIC TONE IN PATIENTS WITH IRRITABLE BOWEL SYNDROME (IBS)EFFECTS OF IV ERYTHROMYCIN (ERY) ON GASTRIC EMPTYING, DUODENO‐CAECAL TRANSIT TIME, GASTRIC AND BILIO‐PANCREATIC SECRETION DURING ENTERAL NUTRITION IN HEALTHY VOLUNTEERS.FOREGUT FUNCTION IN IRRITABLE BOWEL SYNDROME.SUBCELLULAR LOCALISATION OF THE MOTILIN RECEPTOR.MODULATION OF RAT MESENTERIC AFFERENT DISCHARGE BY GRANISETRON AND DEVAZEPIDEAFFERENT INNERVATION OF CIRCULAR MUSCLE IN HUMAN COLONTHE EFFECTS OF ANTAGONISM OF 5HT3RECEPTORS WITH ALOSETRON ON THE TRANSIT OF A MEAL AND THE ILEAL BRAKE IN MAN.ROLE OF 5‐HT4RECEPTORS IN THE REGULATION OF THE MIGRATING MYOELECTRIC COMPLEX IN SHEEP.EFFECT OF THE PUTATIVE MOTILIN ANTAGONIST ANQ‐11168 ON THE MIGRATING MOTOR COMPLEX (MMC) IN CONSCIOUS DOGS.Signal transduction pathways of muscarinic receptors in circular smooth muscle from the rabbit caecumEFFECT OF ZAMIFENACIN, A NOVEL M3RECEPTOR ANTAGONIST, ON GASTRIC EMPTYING AND SMALL BOWEL TRANSIT IN MAN.PROKINETIC BENZAMIDES DO NOT STIMULATE SMALL INTESTINAL TRANSIT IN THE CONSCIOUS RAT.17454 JL, A NEW BENZAMIDE WITH A POTENT COLONIC STIMULANT EFFECT IN RATS AND DOGS.(R)‐ZACOPRIDE INCREASES THE LOWER ESOPHAGEAL SPHINCTER PRESSURE IN THE CONSCIOUS DOG.VB20B7, A NOVEL GASTROKINETIC AGENT WITH 5‐HT, RECEPTOR AGONIST AND 5‐HT3RECEPTOR ANTAGONIST PROPERTIESCISAPRIDE FACILITATES INHIBITORY PURINERGIC‐TRANSMISSION IN THE GUINEA PIG COLON.POST‐OPERATIVE ANTRAL MOTILITY: THE EFFECT OF RECTAL CISAPRIDE.INVOLVEMENT OF 5‐HT4RECEPTORS IN THE GASTROENTEROKINETIC PROPERTIES OF R‐ZACOPRIDE IN THE ANAESTHETIZED DOG.EFFECT OF CISAPRIDE ON THE RABBIT DUODENUM. RELATION TO MOTILIN RECEPTOR.THE STIMULANT ACTION OF LINTOPRIDE, A 5‐HT4RECEPTOR AGONIST, ON THE CANINE ESOPHAGEAL SPHINCTER PRESSURE IS NOT MODIFIED AFTER SUBCHRONIC ADMINISTRATION.FEDOTOZINE MODULATES AUTONOMIC TONE BY POTENTIATING VAGALLY MEDIATED RESPONSES FOLLOWING ESOPHAGEAL STIMULATION IN HEALTHY VOLUNTEERS.EFFECT OF YM060 ON 5‐HT3RECEPTOR MEDIATED MEMBRANE DEPOLARIZATION IN MYENTERIC NEURONS OF THE GUINEA PIG DISTAL COLON.EFFECTS OF CALCIUM CHANNEL BLOCKERS ON HORMONE‐INDUCED CONTRACTION OF ISOLATED GASTRIC SMOOTH MUSCLE CELLS.BIOCHEMICAL CHARACTERIZATION AND QUANTIFICATION OF ENKEPHALINS IN BRAIN, PREVERTEBRAL GANGLIA AND DIGESTIVE TRACT: A COMPARATIVE STUDY ON CATS, GUINEA‐PIGS AND RATSSEGMENTAL LOCALISATION OF MYOGENIC PACEMAKER REGIONS IN THE RAT ILEUM IN VITROASSESSMENT OF ARGYROPHILIA IN THE DEVELOPING HUMAN MYENTERIC PLEXUSTWO INDEPENDENT PACEMAKERS DRIVE THE ELECTRICAL AND MECHANICAL ACTIVITIES OF THE CANINE ILEUM.THE EFFECT OF NON‐ADRENERGIC, NON‐CHOLINERGIC TRANSMISSION AND PEPTIDES ON HUMAN ISOLATED COLON SMOOTH MUSCLEDIFFERENT LOCATION OF TONIC CONTRACTION PATTERNS IN ISOLATED HUMAN, CANINE AND PORCINE DUODENUM.NONADRENERGIC‐NONCHOLINERGIC (NANC) NERVE MEDIATED RELAXATIONS IN THE OPOSSUM (Didelphis albiventris) ILEOCOLONIC JUNCTION (ICJ).BOMBESIN‐RELATED PEPTIDES STIMULATE CAT SMALL INTESTINAL SMOOTH MUSCLE VIA GASTRIN‐RELEASING PEPTIDE‐PREFERRING RECEPTOREFFECTS OF THYROID HORMONES ON ISOLATED CIRCULAR MUSCLE OF RAT COLON.EFFECTS OF ALVERINE ON ELECTRICAL PROPERTIES OF VAGAL AFFERENT NEURONS IN ISOLATED RABBIT NODOSE GANGLIA.INFLUENCE OF NEUROTENSIN ON MECHANICAL ACTIVITY IN RAT PROXIMAL COLON.IN VITROCONTRACTILITY OF THE RAT INTESTINAL LONGITUDINAL SMOOTH MUSCLE (ILSM) IN RESPONSE TO SHORT CHAIN FATTY ACIDS (SCFA).EFFECT OF SHORT‐CHAIN FATTY ACIDS ON PRIMARY CULTURE OF COLONIC AND ILEAL SMOOTH MUSCLE CELL.EFFECTS OF CHOLECYSTOKININ ON CHICKEN COLON. STUDY OF ITS INVOLVEMENT IN THE GASTROCOLIC RESPONSE.Role of NO in regulation of antral motility and hormones release in humans.EFFECTS OF CHOLECYSTOKININ OCTAPEPTIDE (CCK‐OP) ON THE TONIC AND PHASIC MOTOR ACTIVITY OF THE HUMAN COLON.PRESERVED INTENSITY OF THE MIGRATING MOTOR COMPLEX IN SMALL INTESTINE AFER CHRONIC BILIARY DIVERSION IN RATSEVIDENCE OF THE PRESENCE OF AN “ILEAL BREAK” MECHANISM IN AVIAN SPECIES.THE ACTIONS OF MORPHINE ON MESENTERIC AFFERENT DISCHARGES IN THE RAT.EFFECTS OF PSYCHOLOGICAL STRESS ON COLONIC AND SMALL BOWEL MYOELECTRICAL ACTIVITY AND BEHAVIOR.EFFECTS OF ENVIRONMENTAL STRESS ON GASTRIC EMPTYING.ILEAL VOLATILE FATTY ACIDS INHIBIT GANIC MYOELECTRlC ACTIVITY IN RATS.RECEPTORS INVOLVED IN THE INHIBITION OF FORESTOMACH MYOELECTRICAL ACTIVITY BY SEROTONIN IN SHEEP.EFFECTS OF SOMATOSTATIN ON FLOW RATE, TRANSIT TIME AND ABSORPTION OF NUTRIENTS IN PIGS.EXCITATION OF SMALL INTESTINE MECHANORECEPTORS ALTERS NEURONAL ACTIVITY OF THE SPINAL SUBSTANTIA GELATINOSAEFFETCS OF FEEDBACK CONTROL ON INTESTINAL MOTILITY, FLOW RATE AND TRANSIT TIME IN MINI‐PIGS.DECREASED COLONIC COMPLIANCE AFTER INFERIOR MESENTERIC GANCLIONECTOMY IN DOGS.ASCENDING PERISTALTIC REFLEX CONTRACTIONS IN THE CANINE DUODENUM IS RELATED TO THE PHASE OF THE INTERDIGESTIVE MIGRATING MOTILITY COMPLEX.INVOLVEMENT OF SEROTONIN AND CHOLECYSTOKININ IN THE MOTOR RESPONSE OF THE ILEUM TO ACIDIFICATION IN THE HORSE.FLUCTUATIONS OF BLOOD FLOW IN THE PORTAL VEIN AND GASTRODUODENAL MOTILITY DURING THE MIGRATING MOTOR COMPLEX (MMC) AND FEEDING IN CONSCIOUS DOGS.THE ASSESSMENT OF THE EVACUATORY FUNCTION OF THE SMALL BOWEL IN VARIOUS METHODS OF RECONSTRUCTIVE OPERATIONS ON THE BILIARY TRACT.INFLUENCE OF AGING ON CYCLIC NUCLEOTIDE GENERATION DURING NANC STIMULATION OF THE RAT GASTRIC FUNDUS.EFFECT OF DUODENOPLASTY OR DUODENAL SEGMENTAL RESECTION ON ELECTROPHYSIOLOGICAL AND MECHANICAL ACTIVITY OF THE UPPER GASTROINTESTINAL TRACT.REGIONAL DIFFERENCES IN INTRALUMINAL CROSS‐SECTIONAL AREAS AND DISTENSIBILITY OF THE NORMAL PORCINE OESOPHAGUS AND THE OESOPHAGUS DAMAGED BY ENDOSCOPIC SCLEROTHERAPY.ULTRASTRUCTURAL STUDY OF SPINAL AFFERENTS IN THE MUCOSA OF THE CAT ESOPHAGOGASTRIC JUNCTION WITH FELINE IMMUNODEFICIENCY VIRUS INFECTION.POSITIVE ACTION OF A PAF‐ANTAGONIST (BN 50727) ON THE POST‐ISCHEMIC RECOVERY OF THE JETUNAL MOTILITY IN DOGEFFECTS OF PERIPHERALLY VS CENTRALLY ADMINISTERED CALCITONIN ON MEAL‐ AND CERULEIN‐INDUCED GALLBLADDER EMPTYING IN DOGSMODULATION OF THE MOUSE GALLBLADDER SENSITIVITY TO CCK BY CHRONIC DIETS WITH DIFFERENT PROTEIN COMPOSITION.COMPARATIVE EFFECTS OF ERYTHROMYCIN AND A NEW ERYTHROMYCIN DERIVATIVE, KC 11458, ON POSTPRANDIAL GALLBLADDER EMPTYING IN DOGS.THE EFFECT OF MEAL CALORIC CONTENTS ON GALLBLADDER (GB) MOTOR ACTIVITYA NEW METHOD OF RECORDING COLONIC MOTILITY VIA CHRONICALLY IMPLANTED RADIOTELEMETRY CAPSULES (RTCs): A COMPARISON WITH SEROSAL STRAIN GAUGES (SGs).CONTINUOUS IN‐VIVO MANOMETRY OF THE HUMAN GALLBLADDERORIGIN AND PROPAGATION OF THE SLOW WAVE IN THE ISOLATED FELINE STOMACH AS REVEALED BY HIGH RESOLUTION MAPPING.JEJUNAL CONTROL OF THE TRANSPYLORIC FLOW AND PYLORIC RESISTANCE.SIMULTANEOUS ASSESSMENT OF THE GALLBLADDER CONTRACTION BY MEANS OF REAL‐TIME ULTRASONOGRAPHY AND STRAM GAUGE IN THE DOGMEASUREMENT OF GASTRIC EMPTYING RATE WITH AN INTRAGASTRIC GAMMA PROBE.Dynamics of theChances inMotility, Evacuation andEMGinExperimentalDuodenalStenosis.NONINVASIVE13C‐OCTANOIC ACID BREATH TEST FOR MEASUREMENT OF SOLID GASTRIC EMPTYING: REPRO‐DUCIBILITY IN HEALTHY VOLUNTEERS AND COMPARISON TO SCINTIGRAPHY IN DIABETICS.COMPUTER SWPORTED ANALYSIS OF AMBULATORY MANOMETERIC RECORDINGS IN THE HUMAN SMALL BOWEL ALGORITHM AND VALIDATIONCONTRACTILE PATTERNS IDENTIFIED BY COMPUTER ANALYSIS IN PATIENTS WITH SMALL INTESTINAL PATHOLOGYNON‐ULCER DYSPEPSIA (NUD): IS USONOGIUPWTF DIAGNOSTIC USE?Electrogastrography in non‐ulcer dyspepsia: Back to square one?FUNCTION OR IMAGE: EMG VERSUS ENDOSONOGRAPHY TO DETECT ANAL SPHINCTER DEFECTS.CHOLESCINTIGRAPHIC EVALUATION OF EXTRAHEPATIC BILE TRANSIT AS AN INDIRECT TEST OF SPHINCTER OF ODDI MOTOR FUNCTION.DIFFERENT DIAGNOSTIC PROCEDURES IN THE EVALUATION OF ESOPHAGEAL MOTOR DISORDERS IN GASTROESOPHAGEAL REFLUX DISEASE (GERD)VIDEO BARIUM ESOPHOGRAPHY (VBE). A SIMPLE METHOD TO EVALUATE ESOPHAGEAL MOTILITY DISORDERS IN GASTROESOPHAGEAL REFLUX DISEASE (GERD).TEMPERATURE DEPENDENCE OF ESOPHAGEAL MOTOR FUNCTION IN MAN REVISITEDIS THE MANOMETRIC EVALUATION OF THE LOWER ESOPHAGEAL SPHINCTER CLINICALLY USEFUL?24–HOUR AMBULATORY ESOPHAGEAL MANOMETRY IN NORMAL SUBJECTS (Cooperative study).EFFECTS OF ESOPHAGEAL STIMULATION ON CARDIAC AUTONOMIC FUNCTION IN MAN.THE ROLES OF THE PROXIMAL AND THE DISTAL STOMACH IN MODULATING GASTRIC EMPTYING.DIFFERENT EFFECTS OF WHITE WINE AND RED WINE ON GASTROESOPHAGEAL REFLUX.RELATIONSHIP BETWEEN INTERDIGESTIVE ESOPHAGEAL AND GASTRIC MOTILITY IN HUMANS.SIMULTANEOUS MEASUREMENT OF GASTRIC TONE AND ANTRAL MOTILITY AFTER A SOLID MEAL IN HUMANS.Effects ofNitric oxide(NO)on gastric emptying andDrocecalTransitTimePATTERN OF GASTRIC EMPTYING AND ANTRODUDOENAL MOTILITV AFTER GLUCOSE INGESTION.EFFECT OF BRAN PARTICLE SIZE ON GASTRIC EMPTYING AND SMALL BOWEL TRANSIT OF FOOD AND BRANCOMPARISON OF DUODENOJEJUNAL (DJ) MOTOR ATTERNS AFTER ORAL AND DURING ENTERAL UTRITION (EN) IN MAN.MMC‐RELATED DUODENOJERINAL ANTEGRADE AND RETROGRADE PERISTALSIS IN HUMANS.THE EFFECT OF PSYCHOLOGICAL STRESS AND AN OPIOID AGONIST ON POSTPRANDIAI. MOTOR ACTIVITY IN THE HUMAN SMALL BOWEL.COMPARISON BETWEEN PHYSIOLOGICAL AND TRYTHROMYCIN INDUCED INTERDIGESTIVE MOTILITY.EFFECTS OF A CHRONIC SUPPLEMENTATION OF THE USUAL DIET WITH DIETARY FIBERS ON 24 HOUR COLONIC MOTILITY IN MAN.VALUE OF ESOPHAGEAL LONG TERM PHMANOMETRY IN PROGRESSIVE SYSTEMIC SCLEROSIS ‐ A COMPARISON WITH TRANSIT SCINTIGRAPHYEFFECTS OF GASTRIC DISTENSION,&DUODENAL INFUSION OF ACID, 5% NaCI&OLEATE SOLUTIONS&STROKE VOLUME ON ANTRODUODENAL MOTOR RESPONSES.PATIENTS WITH DIFFUSE ESOPHAGEAL SPASM SHOW AN ABNORMAL ESOPHAGO‐CARDIAC INHIBITORY REFLEXEFFECTS OF NIFEDIPINE ON PERCEPTION OF ESOPHAGEAL DISTENSION IN PATIENTS WITH NON CARDIAC CHEST PAINPERMISSIVE ROLE OF TEE ESOPEAGEAL BODY DURING TRANSIENT LES RELAXATIONS (TSLESRs). A MECEANISM FOR INCREASED ACID REFLUX IN PATIENTS WITH REFLUX ESOPBAGITIS.DO ESOPHAGEAL AND GASTRIC FUNCTIONAL STUDIES PREDICT CLINICAL COURSE OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN?MOTILITY DISORDERS OF THE ESOPHAGUS IN PRIMARY SJOGREN'S SYNDROMEDYNAMIC CHARACTERISTICS OF GASTRO‐OESOPHAGEAL REFLUX IN AMBULATORY GORD PATIENTS MEASURED WITH A 5–CHANNEL pH CATHETER.ACHALASIA: MALFUNCTION OF THE INTRINSIC INNERVATION BUT PRESERVED SENSITIVITY TO NITRIC OXIDE.THE EFFECTIVENESS OF BENZODIAZEPINE HYDROCHLORIDE /TILDIEM IN ACHALSIA PATIENIS.THE EFFECTS OF NITRIC OXIDE (NO)‐RECEPTOR STIMULATION IN PATIENTS WITH ACHALASIA.GASTRIC EMPTYING RATE IN RELATION TO AUTONOMIC AND PERIPHERAL NEUROPATHY AND BLOOD GLUCOSE IN 52 PATIENTS WITH INSULIN‐DEPENDENT DIABETES.GASTRIC EMPTYING IN CHILDREN WITH GASTRIC TRANSPOSITIONCCK IN THE CONTROL OF GASTRIC MOTOR AND SECRETORY RESPONSE IN NOW AND DUODENAL. ULCER (DU) PATIENTS.GASTRODUODENAL MOTILITY IN HIRSCHPRUNG'S DISEASEGASTRIC ULTRASONOGRAPHY IN CHILDREN PRESENTING WITH SYMPTOMS OF UPPER INTESTINAL DYSFUNCTION.INTESTINAL MANIFESTATION OF POLYMYOSITIS ‐ RARE OR RULE?DUODENO‐GASTRIC BILIARY REFLUX FOLOWING LAPAROSOOPIC CHO‐LECYSTECTOMY.SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND CHRONIC INTESTINAL PSEUWOBSTRUCTION (CIPO).SMALL BOWEL MOTILITY IN INTENSIVE CARE UNIT (ICU) PATIENTS: FASTING PATTERN AND MOTILIY RESPONSE TO ENTERAL NUTRITION.SLOW TRANSIT CONSTIPATION, A RESULT OF SELECTIVE AUTONOMIC DEFCITS?JEJUNAL MANOMETRY IN PATIENTS WITH THE SHORT BOWEL SYNDROME (SBS) AND INTERPOSITION OF A REVERSED SMALL BOWEL LOOP (RSBL).ABDOMINO‐PERINEAL DYSSYNERCIA AS WELL AS CHRONIC Neurogenic LESIONS OF THE EXTERNAL ANAL SPHINCTER MAY CAUSE OBSTRUCTED DEFAECATION.MECHAINSMS OF Anorexia AND VOMITING IN CHILDREN WITH CHRONIC RENAL FAILURE: 1) GASTROESOPHAGEAL MOTILITY.DyspepsiaIN Aids: RelationsshipBettweenSymptomsAndFindings ofFunctionalULTRASONOGRAPHY.MECHANISMS OF ANOREXlA AND VOMITING W CHILDREN WITH CHRONIC RENAL FAILURE: II) POLYPEPTIDE HORMONES.IDENTIFICATION OF IRRITABLE BOWEL SYNDROME (IBS) BY COMPUTER ANALYSIS OF PROXIMAL SMALL BOWEL MOTOR ACTIVITY.SMALL BOWEL MOTILITY IN THE IRRITABLE BOWEL SYNDROME WITH PREDOMINANT DIARRHEA.CHRONIC IDIOPATHIC CONSTIPATION AND DISTRIBUTION OF VIP‐ AND NITRIC OXIDE SYNTHASE (NOs) IMMUNOREACTIVE NEURONS AT THE VARIOUS COLONIC LEVELS.CHRONIC CONSTIPATION PATIENTS ARE PSYCHOLOGICALLY DIFFERENT FROM FUNCTIONAL DYSPEPSIA AND IBS PATIENTS.DOES BIOFEEDBACK TREATMENT OP

ISSN:1350-1925    

DOI:10.1111/j.1365-2982.1994.tb00181.x

出版商:Blackwell Publishing Ltd    

年代:1994

数据来源: WILEY