ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Ferrugination of fibrin, dermal collagen, and striated muscle fibers may result from the application of Monsel's solution (20% ferric subsulfate) for hemostasis to wounds caused by excisions of skin. The collagen fibers in the dermis are coated with a slightly refractile, graybrown substance which is strongly positive with Perl's reaction for iron. Ferruginated collagen fibers are eliminated through the epidermis as the epidermis regenerates. Some of the ferruginated fibers become calcified. Siderophages are present in these and adjacent areas. Secpage of Monsel's solution into deeper tissues at the site of biopsy may result in ferrugination of skeletal muscle, perichondrium, and even eartilage.We applied Monsel's solution to biopsy sites caused experimentally in a rabbit and confirmed the capacity of the solution to produce ferrugination of collagen fibers and skeletal muscle. Ferrugination of collagen fibers becomes less pronounced as the wounds heal and as iron pigment is taken up by macrophages. Ferruginated fibers of skeletal muscle act as foreign bodies to elicit a granulomatous reaction. Comparison of biopsy sites to which Monsel's solution had been applied with biopsy sites to which the solution had not been applied indicates that the substance does not seem to interfere with the rate of epidermal regeneration. However, when there is injury to skeletal muscle and other deep tissues by Monsel's solution, an inflammatory reaction persists at these sites for weeks.

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Trichilemmoma is a follicular tumor because of its resemblance to follicular outer root sheath, overlapping features with other tumors in the spectrum of benign follicular neoplasms, occurrence as multiple dominantly inherited and solitary noninheritable tumors, and occasional complication of organoid nevus. The dangerous misinterpretation that trichilemmomas are viral warts, unsupported by scientific evidence, has harmed patients. All electron-microscopic, immunologic, and clinical transmission attempts to demonstrate viral etiology of trichilemmoma have failed. If trichilemmomas were simply old warts, we might expect to see them frequently in children, extrafacially, of long duration, associated with multiple authentic (“young‘’) warts, as multiple lesions, and associated with authentic warts in patients with Cowden's syndrome (multiple trichilemmomas). Actually, trichilemmomas are rarely seen in children, extrafacially, of long duration, associated with multiple authentic warts, as multiple lesions in patients without Cowden's syndrome, and associated with authentic warts in Cowden's syndrome. Unfortunately, patients with multiple trichilemmomas, Cowden's syndrome, and associated internal disease have been passed off as “simply old viral warts.‘’ The missed opportunity to identify women with a 50% risk of brast cancer is a disservice to the patient, to say nothing about malpractice implications for the physician when generally accepted medical standards are not applied.

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Lupus erythematosus is one of the most complex and protean diseases in dermatology. In contrast to the changing concepts of its still unknown cause and pathogenesis over the last century and a half, the title lupus erythematosus has remained unchanged since it was first adopted around 1870. How this designation came to be is the theme of this paper.

ISSN:0193-1091    

出版商:OVID    

年代:1980

数据来源: OVID