摘要:

A bone scan in a patient with proved osteogenic sarcoma of the tibia showed intense focal uptake in the gluteal region on the side of his cancer. This was proved to be a metastasis in the muscle.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Chylous effusion is an infrequent complication of cardiothoracic surgery and a less frequent complication of central line placement. The authors describe a novel application of lymphoscintigraphy showing thoracic duct injury in an infant after surgery for hypoplastic left heart syndrome.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Hypophosphatemic osteomalacia, a familial or rarely acquired disorder, is characterized biochemically by hypophosphatemia, decreased renal tubular reabsorption of phosphate, decreased intestinal absorption of calcium, and normal serum calcium. This report concerns a rare case of hypophosphatemic osteomalacia of unknown cause that was shown on Tc-99m MDP bone scanning.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Purpose:Endogenous subclinical thyrotoxicosis is diagnosed when a patient who is not taking exogenous thyroid hormone has a suppressed level of thyroid-stimulating hormone with normal levels of the free thyroid hormones thyroxine and triiodothyronine and other known causes of a suppressed thyroid-stimulating hormone level have been excluded. Although such a condition is caused by underlying thyroid disease, the specific nature and relative prevalence of these disorders and the utility of nuclear imaging and other studies in their detection remains unclear.Patients and Methods:The authors performed a retrospective study of 50 patients with endogenous subclinical thyrotoxicosis. The results of the history and physical examination, thyroid nuclear scan, radioactive iodine uptake measurement, and thyroid antibody studies were reviewed. The results of the nuclear imaging and thyroid antibody studies were combined in an attempt to establish an underlying diagnosis for each patient.Results:The thyroid nuclear imaging and antibody studies were used to establish a specific thyroid disorder in most of the patients (n = 39). These disorders included most commonly toxic multinodular goiter, various forms of autoimmune thyroid disease, and solitary toxic adenoma. A specific diagnosis was not determined in 11 patients. Therapy with I-131 radioactive iodine was administered to 14 of these patients, 13 of whom subsequently achieved a normal thyroid-stimulating hormone level.Conclusions:Most patients with endogenous subclinical thyrotoxicosis have underlying thyroid abnormalities that can be determined by nuclear imaging and, in selected cases, thyroid antibody studies.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Radionuclide imaging with Tc-99m MIBI is the preferred mode of parathyroid localization in current practice. It also successfully identifies hyperfunctioning autotransplanted parathyroid tissue. The authors report a case with recurrent hyperparathyroidism after total parathyroidectomy and autotransplantation in the forearm. Double-phase Tc-99m MIBI imaging successfully localized the hyperfunctioning parathyroid tissue, which was missed by magnetic resonance imaging and ultrasonography. In addition, the parathyroid tissue was localized using an intraoperative probe at subsequent surgery.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Purpose:Tc-99m sestamibi (MIBI) uptake in pulmonary sarcoidosis has been reported, but it has never been studied before and during treatment with glucocorticoids.Methods:The authors performed MIBI scintigraphy and somatostatin receptor scintigraphy in a patient with sarcoidosis of the mediastinum, lungs, and liver and who had persistent hyperparathyroidism after unsuccessful neck exploration.Results:Somatostatin receptor scintigraphy showed high mediastinal and pulmonary uptake in a pattern characteristic of sarcoidosis. Sustained MIBI uptake occurred in the same, although smaller, region. After the diagnosis was confirmed by liver biopsy, the patient was treated with glucocorticoids. Repeated MIBI scintigraphy showed that the uptake in the mediastinum had clearly decreased.Conclusions:This decrease of MIBI uptake in the mediastinal lymph nodes with therapy may imply that MIBI can be used to assess the response to treatment in sarcoidosis. Perhaps a relation exists between MIBI uptake at the moment of diagnosis and prognosis. Further studies in more patients are needed to evaluate the role of MIBI in the management of sarcoidosis.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Three cases illustrate the use of a reusable, shielded marker to identify anatomic structures and mark pathologic lesions. No other nuclear medicine marker is available with a shutter mechanism designed to interrupt radiation, thus protecting the patient and technologist from unnecessary radiation and minimizing image artifacts.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography has been used extensively in the diagnosis of malignant conditions with high rates of sensitivity and specificity. However, increased FDG uptake is not limited to malignant tissue. In general, lesions with a mild degree of FDG uptake as measured by standardized uptake values less than 2.0 are considered benign, whereas those with values greater than 2.5 are usually regarded as malignant. Standardized uptake values in the kidney can be as high as 22 as a result of excretion of FDG through urine. Two cases are reported in which renal abnormalities could not be distinguished from urine based on standard uptake values alone.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Purpose:Unusual pulmonary uptake of In-111 chloride in a patient withPneumocystis cariniipneumonia and autoimmune hepatitis is described.Method:In-111 chloride bone marrow scintigraphy was performed to evaluate the bone marrow activity associated with pancytopenia in a 56-year-old woman with autoimmune hepatitis.Results:An In-111 chloride bone marrow scan showed increased pulmonary uptake predominantly in both upper lung fields.P. cariniipneumonia was seen to be developing as an immunocompromised complication after treatment for autoimmune hepatitis.Conclusion:When In-111 chloride bone marrow scintigraphy shows increased uptake in the lungs of immunocompromised patients, a combined opportunistic inflammatory disease such asP. cariniipneumonia should be considered in the diagnosis.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

Purpose:Tc-99m MIBI can be excluded from cytosol against its concentration gradient as a suitable transport substrate by P-glycoprotein. Tc-99m MIBI has also been shown to be more effective than Tl-201 chloride for evaluating the response to chemotherapy in patients with small-cell lung cancer. The relation between Tc-99m MIBI accumulation by the tumor and its response to chemotherapy were evaluated in patients with non–small-cell lung cancer (NSCLC) and compared with the same parameters achieved using Tl-201 chloride.Methods:Thirty-eight patients with NSCLC were examined before chemotherapy was begun. They were classified according to the results of a follow-up computed tomogram into two groups: responders were patients in whom there was a ≥50% decrease and nonresponders were patients in whom there was a <50% decrease in the sum of the product of the maximum perpendicular diameters of all measurable lesions. All patients underwent dual-isotope imaging with Tl-201 chloride and Tc-99m MIBI just before chemotherapy. Regions of interest were placed over the tumor uptake (T) and contralateral normal lung tissue (N) areas on one coronal view with a clearly defined lesion, and the T:N ratio and retention index were calculated.Results:The delayed T:N ratio and retention index for Tc-99m MIBI in the responder group were significantly greater (P< 0.05) than those in the nonresponder group. There was no significant correlation between the T:N ratio and retention index and tumor response using Tl-201 chloride.Conclusion:Tc-99m MIBI SPECT may be more effective than Tl-201 chloride SPECT for evaluating the response to chemotherapy in patients with NSCLC.

ISSN:0363-9762    

出版商:OVID    

年代:2000

数据来源: OVID