摘要:

Approximately 25% of metastatic and recurrent differentiated (papillary and follicular) thyroid carcinoma do not concentrate I-131 Nal. In such cases, diagnosis can be attempted with other radiopharmaceuticals. The authors present a case of recurrent papillary thyroid carcinoma that was well visualized with Tc-99m sestamibi and ln-111 pentetreotide; but only poorly visualized by I-131 Nal.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Whole-body scintigraphy with radiolodine-131 is an important diagnostic test in the management of patients with differentiated thyroid cancer who have undergone surgical treatment. The scan can demonstrate the presence of residual thyroid or functioning metastases in lymph nodes or distant sites. However, there are a number of potential pitfalls in the interpretation of this scan that could lead to a false-positive diagnosis of cancer. The scintiscans are presented for five patients in whom uptake outside of the thyroid was not due to functioning metastases. Some of these abnormalities are physiologic, such as uptake of iodine in the gastrointestinal tract. A comprehensive list of false-positive results are tabulated.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

This case report describes an I-131 whole-body scan with false-positive uptake at the site of a nose ring in a patient with follicular thyroid cancer.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Radionuclide thyroid angiography was performed in 252 patients with hypofunctioning thyroid nodules to evaluate differences in vascular flow and washout patterns in benign and malignant disease. Time activity curves of Tc-99m pertechnetate flow through the cold nodules were generated using region of interest software. Retention ratios of counts in the nodule at 2 minutes after radionuclide administration versus those at peak activity were derived. Patients subsequently underwent surgical excision and histopathologic examination. One hundred forty-four of the 204 benign nodules were avascular with absent radionuclide flow through the nodule. Fifty-six benign nodules were vascular with a prolonged radionuclide washout pattern with retention ratios ranging from 0.60−0.92. Forty-six of the 48 malignant nodules displayed increased perfusion with rapid radionuclide washout with retention atios ranging from 0.28−0.48. Four benign nodules exhibited a similar flow and washout pattern. Radionuclide thyroid angiography with vascular flow and washout analysis appears to be a useful technique to differentiate between benign and malignant thyroid nodules with a high degree of sensitivity and specificity.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

In a study group of 20 healthy young men, splenic volume was determined with SPECT before and after exercise. A randomly chosen control group of 10 comparable men was studied similarly, but without exercise intervention. The mean splenic volume did not change significantly in the control group (i.e., from 292.9 ml to 282.1 ml [P=0.75]). The mean splenic volume decreased 60.1 ml from 279.4 to 219.3 ml (21.5%) in the study group and this was highly significant (P=0.01). Although exercise induced splenic autotransfusion is generally considered to be unimportant in humans, significant splenic contractility was observed with this technique. In the normal individual with a large spleen or with functional splenomegaly, the contractility response may become more important and can now be measured in a quick and easy manner.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Hepatobiliary scintigraphy performed in a patient suspected of having common bile duct obstruction showed persistence of the hepatic parenchymal phase and no bile duct or gallbladder activity during the first hour of imaging. On endoscopic retrograde cholangiopancreatography examination several hours later, an obstructing gallstone was identified in the common bile duct, and the stone was extracted in conjunction with a papillotomy. Delayed scintigraphic images at 6 hours were unchanged from the earlier views, but imaging at 24 hours showed tracer activity in the small bowel and colon along with persistent hepatic parenchymal activity. These results demonstrate that hepatobiliary radiopharmaceuticals remain in an excretable form in the liver in patients with complete common duct obstruction, but that resumption of bile flow and tracer excretion does not occur until a number of hours after relief of the obstruction.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Fifteen patients with the clinical and radiologic features of autosomal recessive polycystic kidney disease were investigated with radionuclide hepatobiliary scintigraphy. In nine patients (60%), cholestasis and intrahepatic bile duct dilatation were demonstrated. A 10th child had scintigraphic evidence of cholestasis, but the bile ducts were not dilated. The other five children had normal hepatobiliary scans. The authors conclude that intrahepatic bile duct dilatation with cholestasis (Caroll's disease) Is part of the clinical spectrum of autosomal recessive polycystic kidney disease and that hepatobiliary scintigraphy can be of value in determining the extent of hepatobiliary disease in this group of patients.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

Gastrinomas are usually diagnosed clinically and localized before surgery using various imaging modalities including ultrasound, computed tomography, magnetic resonance imaging, angiography, and venous sampling. The authors present a case in which CT, MRI, and angiography were negative in attempting to localize the gastrinoma, but In-111 pentetreotide localized the lesion, which was proven surgically.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

The authors present a case of thrombosis involving the right common iliac vein evaluated with subcutaneous radionuclide venography (SCRNV) after injection at acupuncture points. SCRNV demonstrated interruption of venous flow to the right common femoral vein and right iliac vein with prominent collateral venous drainage into the contralateral deep veins. This technique, which is technically simple and relatively operator-independent, has the potential to become a screen or follow-up test for deep vein thrombosis.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID

摘要:

A 42-year-old woman with hyperparathyroidism had a CT scan that was suggestive of a small nodular lesion in the left lower neck. Tc-99m sestamibi and Tc-99m tetrofosmin parathyroid imaging were performed 10 minutes and 2 hours after tracer injection. Early imaging with Tc-99m sestamibi demonstrated thyroid and focal uptake in the left lower neck. On delayed imaging, findings suggested a parathyroid adenoma. Imaging with Tc-99m tetrofosmin demonstrated similar findings. The abnormal parathyroid gland was an adenoma.

ISSN:0363-9762    

出版商:OVID    

年代:1995

数据来源: OVID