摘要:

Twenty-two painful hip prostheses were studied prospectively with plain radiography, aspiration and arthrography, Tc-99m phosphate bone imaging, and gallium imaging to evaluate loosening, infection, or both and to compare the accuracy of these modalities. Fifteen pros-theses were revised yielding 14 loose femoral and eight loose acetabular components. Five proved to have infected prostheses. Arthrograms, plain radiographs, and bone scans are highly sensitive in detecting loosening of the femoral component. This study confirmed a previous retrospective study in demonstrating that accuracy of diagnosis of an abnormal acetabular component using all tour modalities is less than that for the femoral component. In infected prostheses, phosphate bone imaging showed high sensitivity of a pattern that accurately diagnosed all the infected cases, whereas gallium imaging missed one case.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The utility of Tc-99m BBC imaging in the diagnosis of hepatic cavernous hemangiomas has been established. Of the 25 patients with various focal hepatic lesions evaluated, 16 were diagnosed as having hemangiomas: eight proven by surgery, two proven by angiography, and six proven by maintaining a stable clinical course ranging from 6 to 12 months with normal follow-up liver function tests. Although fourteen of these were detected by planar imaging, two were detected by SPECT only. Two patients with large hemangiomas had false-negative scans, whereas the remaining seven patients had other liver lesions.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Fibrous dysplasia is an uncommon bone condition with characteristic radiologic features. It is well known that there is increased uptake of Tc-99m hydroxymethylene diphosphonate (HMDP) and methylene diphosphonate (MDP) in fibrous dysplasia. There are no reports of uptake of Ga-67 citrate by fibrous dysplasia. A case is reported in which positive Ga-67 uptake was seen in a patient with polyostottc fibrous dysplasia.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

In two panels totaling 52 patients with melanoma who were imaged with In-111 labeled 96.5 or ZME-018 (ZME) monoclonal antibodies (MoAb), four patients demonstrated numerous metastases (≥20) in the subcutaneous tissues and peripheral lymph nodes. These constituted four intrapatient groups of tumors. These were selected for an intrapatient comparison of tumor size and uptake. Data on 16 additional patients imaged with 96.5 MoAb with fewer (≤11) such tumor foci were pooled and used as an interpatient control group of tumors. Uptake was graded 0–5+ (liver = 4+). The data were similar in all live groups. All tumors with a diameter less than 0.7 cm were not detected. All large tumors were demonstrated, usually with high uptake. Small tumors (≥ 0.7 cm in diameter), however, showed variable uptake, from 0–4+. Thus, tumors within one patient were as variable in uptake as tumors between patients. Immunologic studies of melanoma tumor antigens have shown a similar variability. It is suggested that antigenic heterogeneity is responsible for the variable scintigraphic demonstration of such tumors.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Magnetic resonance imaging (MRI) was compared with radionuclide scintigraphy (RNS) in 16 patients with renal transplants undergoing renal failure to determine which modality could best discriminate between rejection, acute tubular necrosis (ATN), and cyclosporin nephrotoxicity (CN). Although all rejecting transplants had reduced corticomedullary dilferenttation (CMD) on T1-weighted MR images, four of live cases of ATN had appearances that could not be distinguished from rejection. A normal CMO suggests nonrejection, but diminished CMO is nonspecific. Tc-99m DTPA/I-131 hippuran RNS was superior to MRI In differentiating rejection from ATN. Although ATN and CN have similar RNS patterns, this distinction can usually be made based on the clinical time course. Other potential uses of MRI in the evaluation of the renal transplants are discussed.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Amiodarone is an iodinated antiarrhythmic agent that is effective in the treatment of atrial and ventricular arrhythmias. A number of side effects are seen, including pulmonary loxicity and thyroid dysfunction. A patient with both amiodarone-induced pneumonilis and hyperthy roidism who exhibited abnormal gallium activity in the lungs, as well as diffuse gallium uptake in the thyroid gland is presented. The latter has not been previously reported and supports the concept of iodide-induced “thyroiditis” with gallium uptake reflecting the inflammatory response.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A 47-year-old man with multiple endocrine neoplasia (MEN) type 2a syndrome in whom metaiodobenzyl-guanldine (MIBG) concentrated in lesions from metastatic medullary carcinoma of the thyroid is reported. A somatostatin analogue (Sandostatin SMS 201–995) alleviated the symptoms of Hushing and diarrhea associated with the elevated calcitonin levels but it did not alter either the course of the disease or the MIBG images. A review of the literature is presented of the noncatechoiamine secreting tumors associated with MIBG uptake. Similarities between this case and metastatic carcinoid syndrome are discussed.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A 77-year-old man wilh prostate cancer was serially evaluated for bone metastases using Tc-99m methylene disphosphonate (Tc-99m MOP) both on and off treatment with etidronate disodium (EHDP). While the patient was receiving the medication only minimal bony uptake ot the tracer was seen with the majority remaining in the soft tissues. The similarly structured EHDP probably saturated the binding sites that the radioactive MDP usually adheres to. Physicians should be aware of this interaction and may have to wait until the EHDP has been discontinued for several months before performing bone imaging on these patients.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

In the metastatic work-up of a patient with a malignant lung tumor and cerebrovascuiar disease, bone imaging was performed which showed abnormal uptake in the right parietal region. Emission computed tomography indicated that this was due to intracranial disease and revealed a wedge-shaped pattern indicative of cerebral infarction. A later follow-up study showed complete clearance of the abnormal uptake.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Differentiation of occult skeletal injuries from early acute osteomyelitis in infants and young children is important clinically. The Tc-99m MDP scintigraphic findings in six patients who had occult femoral or tibia) fractures were reviewed. The images obtained early (at 1–4 days from the onset of symptoms) shared the common characteristic finding of a subtle but definite, generalized increased uptake of the tracer along the entire length of the injured bone. This pattern of uptake was similar regardless of the type of fracture. These were different from the focal abnormalities that have been observed in early acute osteomyelitis. In the absence of an extensive cellulitis or a vascular occlusive disease, a bone image showing a mild diffuse uniform increased uptake along the entire length of the tibia or femur in infants and young children with tower extremity pain of less than 1 week's duration should suggest the diagnosis of occult skeletal fractures.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID