摘要:

In a patient with an ovarian dysgerminoma, intense up-take of gallium-67 citrate was demonstrated. This report indicates that dysgerminoma should be added to the list showing abnormal accumulation of gallium-67 citrate in the abdomen.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

A congenitally or developmentally small right kidney in an adult spinal cord injury patient had only 12% of total uptake on radioiodine-labeled orthoiodohippurate renography but nevertheless had a normal-shaped time-activity curve. In a subsequent retrospective review of 175 consecutive radioiodine-labeled ortholodohippurate renograms performed on adult patients over a 3-years period, 35 other patients with studies showing greater than 2:1 asymmetry in renal function were identified. Uptake, clearance or both were abnormal in all 35 kidneys with less than 33.3% of function, with the left kidney more commonly affected (N = 24). Correlation from ultrasound, computerized tomography, intravenous pyelography, and angiography demonstrated acquired abnormalities associated with all 35 of these kidneys, including urinary obstruction (n = 20), renal artery stenosis (n = 9), and cortical scarring/Infection and/or reflux (N = 15) (some patients had more than one diagnosis). While acquired renal function asymmetry almost always results in a smaller kidney with abnormal uptake or clearance characteristics, a congenitally small kidney may have overall reduced blood flow but still display a normal-shaped time-activity curve on radionuclide renography.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

The authors present a case in which a Tc-99m pertech-netate scan revealed a missed torsion of an undescended testis in a 7-month-old boy who presented with persistent pain in the right inguinal region for 3 days.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Eleven patients who underwent nuclear medicine bone scanning were reviewed to determine the incidence of bone scan abnormalities associated with hepatoblastoma. Of these, six patients had abnormal bone scan findings–four with focal involvement. Correlating plain radiographs and/or follow-up nuclear bone scans were available for three of these four. All plain films indicated the presence of osteoporosis. Follow-up scans showed improvement or resolution of abnormalities. None of the patients had documented metastatic bone disease. While there has been no prior reported association, the authors attribute the abnormal bone scan findings to a paraneoplastic syndrome of osteoporosis associated with this primary tumor. They conclude that bone scanning is not routinely indicated in the initial diagnostic staging of hepatoblastoma.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Tc-99m hexamethylpropylene amineoxime (HMPAO) brain perfusion SPECT was correlated with CT, MRI, and clinical findings in 17 patients with acute and subacute aphasia to determine its diagnostic potential in the early phases of stroke-associated language dysfunction. SPECT was performed using a dedicated brain imaging system after intravenous injection of 20 mCI (740 MBq) of Tc-99m HMPAO. Transaxial and three-dimensional surface rendered images were evaluated visually, and perfusion defects were correlated with CT, MRI, and a standard battery of clinical tests for aphasia. Clinical examination was insufficient for anatomic localization of aphasia in more than 40% of patients. CT exams were normal in 5 patients, although SPECT demonstrated perfusion defects in all 17. Nonfluent aphasia was present in only 6 of 10 patients with perfusion defects in Broca's area and fluent aphasia was present in only 5 of 10 patients with lesions in Wernicke's area. Auditory comprehension defect was associated with perfusion defects in the inferior parietal region in 9 of 12 patients (P = 0.05); reading and writing abnormalities were associated with perfusion defects in the posterior frontal, superior and inferior parietal cortex, and superior temporal gyri, and repetition deficit was associated with defects involving the inferior parietal cortex, the supramarginal and angular gyri, and the ipsilateral thalamus in 8 of 11 patients (P < 0.05). Brain perfusion SPECT should be included in the initial evaluation of aphasic patients, because clinical tests of aphasia and morphological imaging have limited value for accurately determining the extent and location of functional deficits.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

A 69-year-old woman presented with non-Hodgkin's lymphoma of the right ilioinguinal region in whom bilateral uptake of Ga-67 in hilar lymph nodes was noted on thoracic SPECT. There were no Ga-67 abnormalities elsewhere within the thorax, and a chest CT scan was also normal. The patient received radiotherapy to the inguinal region and remained in clinical remission for 28 months following treatment. She subsequently relapsed at a number of peripheral lymph node sites, but not in the chest. The authors postulate that isolated hilar uptake of Ga-67 SPECT may not be clinically significant in some untreated patients with lymphoma. This scintigraphic finding should be interpreted cautiously, particularly when other chest imaging studies remain negative.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

A patient with idiopathic retroperitoneal fibrosis with a positive Ga-67 scan was successfully treated with steroids. Administration of methylprednisolone improved the ureteral obstruction and gallium accumulation also disappeared.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

In this preliminary study, four patients suspected of having pulmonary emboli underwent ventilation imaging after inhaling approximately 1 mCi (37 MBq) of Tc-99m Pertechnegas (micro aerosol carbon particles labeled with Tc-99m) in five breaths or less. Planar images in multiple projections were recorded for preset counts. A final posterior image was acquired to evaluate residual lung background activity. Immediately following ventilation imaging, perfusion imaging in the identical projections was performed using 4 mCI (148 MBq) of Tc-99m MAA.Two of the four patients demonstrated matched uniform ventilation and perfusion and two showed segmental ventilation-perfusion “mismatched” defects consistent with pulmonary emboli. In each case, residual Pertechnegas background lung activity (count rate) at the end of the last ventilation image was less than 10% of the initial Tc-99m MAA counts (count rate).The advantages of Pertechnegas, in comparison to aerosolized DTPA, include: less residual ventilation image activity superimposed on the MAA perfusion images, reduced demand for patient cooperation due to fewer required breaths (five or less), and lack of deposition of activity in the central airways. The authors conclude that Pertechnegas has properties that make it ideally suited for routine lung ventilation imaging.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

The author reports a case of metastatic pheochromocytoma to bone imaged with 1–131 MIBG. The “MIBG super scan” pattern is described and is characterized by marked increased uptake in bone with essentially complete absence of activity in the liver and bladder. The avid bony metastases “steal” activity from the liver, as well as from the kidneys and soft tissues. This is felt to be comparable to the “super scan” in bone scintigraphy, whereby bony metastases “steal” activity from the kidneys and soft tissues.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Insular carcinoma of the thyroid appears to represent an entity situated morphologically and biologically in an intermediate position between the well-differentiated and undifferentiated (anaplastic) tumors. The retention of 1–131 concentrating ability by this variant, unlike anaplastic, is very encouraging and amenable to detection and therapy by radioiodine after initial aggressive surgery. A 46-year-old man with a histologic label of anaplastic thyroid carcinoma has had an unusually prolonged disease-free survival and histopathologic review confirmed insular carcinoma. Postoperative radioiodine evaluation revealed avid concentration of tracer in the thyroid bed. Thus, it is possible to ablate with radioiodine. The insular carcinoma should be considered as a distinct clinicopathologic entity and widespread awareness of this variant of tumor may help pathologists, surgeons, and nuclear medicine practitioners to aggressively treat the condition after initial diagnosis.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID