摘要:

A case of intra-abdominalphotopenic mass identified on skeletal and liver-spleen scintigraphy was found to be secondary to a retained surgical sponge.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

A review of 14,296 unselected bone scans identified 889 scans showing absent or faint renal uptake. The majority of cases were associated with renal insufficiency (816/889; 91.8%), while widespread metastatic bone disease was the most common cause in a group of patients without renal disease (53/889; 6.0%). Of the 140 patients with prostate cancer, 108 (77.1%) had evidence of bone metastasis, 19 of whom (17.6%) had evidence of bone renal uptake, demonstrating that poor renal uptake is more frequently associated with prostate cancer than with any other malignancy. Of note was that 162 out of 328 (49.4%) patients with stomach cancer at varying stages showed evidence of bone metastasis, and 14 of them (8.6%) showed poor renal images on bone scan. Interestigly, ankylosing spondylitis and rheumatold arthritls were occasional causes of lack of renal activity (4 and 3 cases, respectively). A case of aduit-form osteopetrosis, showing strikingly increased uptake mainly In the long bones with markedly diminished renal uptake, was also included in this study. Of the 53 bone scans with metastatic disease showing poor renal uptake, 44 (83.0%) revealed evidence of diffuse or multiple metastases in both spine and ribs, while 49 (92.5%) showed malignant involvement in three or more reglons and 35 (66.0%) in four or more regions, suggesting widespread bone involvement in most cases.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

A patient with ovarian carcinoma was evaluated for skeletal metastasis with a routine whole body bone scan. Although no bone metastases were visualized, there was dramatic accumulation of tracer in the soft tissues of the abdomen. CT revealed calcifying soft tissue metastases on the liver surface, the bowel serosa, and in the pelvis corresponding to the abnormal areas of Tc-99m MDP uptake. Tumor necrosis and ongoing calcification within the metastatic sites are possible explanations for this unusual soft tissue concentration of the bone-seeking radiopharmaceutical. In patlents with meatastatic ovarian carcinoma, careful review of extraosseous regions on bone scan images may provide valuable diagnostic information.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

The “cold hip” sign on bone scan is often seen in patients referred with irritable hip. This sign is due to fluid In the hip joint under pressure causing impaired perfusion of the structures within the joint capsule. In a retrospective review, 22% of patients with this sign on bone scan were found to have septic arthritis at surgery. This fact would appear to justify surgical drainage or aspiration of any hip showing this sign on scan. An attempted follow-up study through the medical records was incomplete because of the short follow-up on most patients. The possibility that temporary impairment of blood supply to the head of the femur causes long-term damage to the hip is unanswered on this study, and a long-term recall follow-up study is underway.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Thirteen mentally retarded pediatric patients aged 4 to 13 years with therapy-reslstant epilepsy underwent Tc-99m HMP AO brain perfusion SPECT studies. The results (ab normal in 12 of the 13 patients) were compared with EEG results in 12 of the 13 patients (abnormal in all 12) and x-ray CT in 11 of the 13 patients (normal in 9). Patients with spikes on EEG had foci of increased uptake on HMP AO. This study confirms that HMPAO is sesitive in detecting perfusion abnormalites and localizing epileptic foci in this group of patients.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

We have performed initial clinical studies using the high resolution single photon ring tomograph (SPRINT) and Tc-99m HMPAO. To determine what additional anatomic detail can be depicted using this high resolution, dedicated head, multidetector SPECT device compared to conventional SPECT, six patients with stroke and one normal volunteer were imaged after the injection of 20 mCi Tc-99m HMPAO on a conventional rotating Anger gamma camera (GE-400AC), followed immediately by imaging on SPRINT. Imaging acquisition on the GE-400AC gamma camera was performed using 360 rotation, 64 stops, at 30 seclstop, yielding an average of 985,714 counts for a 10.0 mm thick slice. GE-400AC images were of good quality, having in-plane full width half maximum (FWHM) resolution of approximately 15mm. SPRINT acquisition of image data was performed using both the high resolution and high sensitivity apertures, with data collection over 15 or 20 minutes of imaging time accumulating approximately 500,000 counts and 1,000,000 counts, respectively, from patients in a 10.0 mm thick slice, achieving an in-plane FWHM resolution of approximately 8 mm and 10 mm for the two apertures, respectively.Both image resolution and contrast for visualization of gray, white, and cerebral spinal fluid filled brain structures were improved using SPRINT compared with theGE-4OOAC. We conclude that SPRINT is well suited for brain imaging with Tc-99m HMPAO and is of particular value for applications demanding high resolution.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Sixty-five patients rferred for Tc-99m HMPAO SPECT brain perfusion studies had measurements of global Tc-99m HMPAO retention after injection at rest and after acetazolamide pretreatment. Acetazolamide produced relative changes in Tc-99m HMPAO retention similar to those previously reported with Xe-133 regional cerebvral blood flow (rCBF) measurements. This adition to imaging protocols allows another objective evaluation of the cerebral vascular reserve.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

This report describes a new approach to the evaluation of brain perfusion reserve using Tc-99m HMPAO SPECT. Consecutive brain Tc-99m HMPAO SPECT studies before and after acetazolamide (Diamox) administration were performed within 30 minutes on 19 patients with significant vascular occlusive lesions. Thirteen patients showed decreased perfusion reserve and four patients maintained perfusion reserve in the affected vascular territories after Diamox administration, providing additional information to baseline Tc-99m HMPAO SPECT in 17 (89%) patients. Although flow augmentation post-Diamox was underestimated, possibly due to the nonproportionality of Tc-99m HMPAO activity to true blood flow, significant changes in the brain perfusion pattern were both visually and quantitatively determined using an image subtraction technique. This consecutive Tc-99m HMPAO SPECT technique seems to be of practical use for the evaluation of brain perfusion reserve and for the improvement of the sensitivity of detecting pathologic areas.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Radiation angiopathy was developed by the process of accelerated atherosclerosis at the site of irradiation. The case of a 44-year-old man with right hemiparesis showing a high signal intensity in the left semioval center on MRI and a defect in the left temporo-parietal area with subsequent filling-in with 1–123 IMP brain SPECT is reported. Digital subtraction angiography showed typical radiation angiopathy with ulceration in the left common carotid artery. Twenty-four years previously, he underwent curative irradiation of a neck mass that revealed Hodgkin's disease by biopsy. The emboli formed at the site of radiation-induced angiopathy and caused cerebral infarction. The perfusion abnormality in the territory of theembolic artery was detected by 1–123 IMP SPECT.Long-term survivors of neck irradiation are at high risk for the development of carotid arterial disease and should be watched carefully.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Platelets labeled in vitro with In-111 have a recognized place in the diagnosis of renal transplant rejection. Following their introduction for imaging thrombi, radiolabeled anti-platelet antibodies may also have a role in the diagnosis of transplant rejection. Four of 11 patients with recently donated transplants had biopsy-proven acute rejection episodes close to the time of administration of In-1 11 P256 Fab′ fragment, which recognizes the Ilb-Illa fibrinogen receptor on primate platelets. The transplant-to-background count rate at 3 and 24 hours after these injections were 2.2 (SE 0.14) and 2.3 (0.23), respectively, almost identical to the ratios, 2.0 (0.1) and 2.2 (0.11), recorded at the corresponding times after 19 injections of P256 Fab′ that were remote in timing from rejection episodes. P256 Fab′ may have value in the detection of postoperative venous thrombosis, but it has no value for the detection of transplant rejection.

ISSN:0363-9762    

出版商:OVID    

年代:1991

数据来源: OVID