摘要:

SPECT was used to identify a focal accumulation of cardiac calicification using Tc-99m MDP in a patient with an arrhythmia and known metastatic calcification elsewhere.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A prospective study of 181 patients who underwent SPECT thallium stress imaging produced a sensitivity of 97%, a specificity of 90%, and an accuracy of 93%. Clinically it is often hard to withhold cardiac medications or exclude attempts at diagnosis even after suboptimal stress. These results indicate that tomographic thallium stress testing provides excellent clinical information, even in a relatively unselected population.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Medullary thyroid carcinoma (MTC), a calcitonin-producing tumor that occurs in familial and sporadic forms, can be monitored satisfactorily with measurements of calcitonin and CEA in serum. However, locating the tumor site may be difficult. In the current review of the experience with four new radionuclide tracers for MTC, the relative value of each of these procedures is outlined. Total body imaging using TI-201 chloride and Tc-99m(V) DMSA are both sensitive techniques that can be used for the detection and follow-up of MTC. Imaging using I-131 MIBG and I-131 anti-CEA antibodies/fragments should be performed once the diagnosis and the tumor site have been established, to evaluate if patients might be amenable for therapy with one of these radiopharmaceuticals.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Radiographic contrast agents have been reported in the literature to interfere significantly with red blood cell (RBC) labeling in vivo by Tc-99m. Moreover, in the presence of contrast agents, red cells have been known to undergo significant morphologic changes. These observations led to the current RBC labeling study in patients (N = 25) undergoing procedures with the administration of contrast media. Before and after contrast administration, blood samples were drawn from each patient into vacutainer tubes containing heparin and RBC labeling was performed using 1-ml aliquots of these samples following the Brookhaven National Laboratory protocol. The differences in average percentage labeling yield with and without contrast media were not significant. In vivo labeling in hypertensive rats with administration of contrast media up to 600 mg likewise consistently gave high labeling yields at all concentrations. Purported alterations in cell labeling attributed to contrast agents are not reflected in these studies, and other pathophysiologic factors need to be identified to substantiate the previous reports. In vitro study offers a potentially useful and simple method to delineate effects of various agents on cell labeling.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Radionuclide angiography is useful in monitoring cardiotoxicity of doxorubicin, but in vivo RBC labeling in these patients is believed to be poorer than that in general patients. The left ventricle-to-background activity ratio (R) was not significantly lower in patients treated with doxorubicin (3.24 ± 1.15, N = 13) than in control patients (3.89 ± 1.60, N = 14). With both modified in vivo and in vitro labeling, R was significantly improved in patients treated with doxorubicin (4.37 ± 0.91, N = 8, and 4.37 ± 1.22, N = 13, respectively). However, with the modified in vivo method, labeling efficiency remained a function of hematocrit, whereas the in vitro method removed this dependency. Both modified in vivo and in vitro labeling result in improved image quality over in vivo labeling in patients treated with doxorubicin, and the choice of method can be based on other factors.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

This case report presents clinical, scintigraphic, duplex sonographic, and biopsy findings in a 23-year-old female renal allograft (RAG) recipient, who had transplantation for chronic renal failure secondary to hemolytic uremic syndrome (HUS). She demonstrated acute and rapidly progressing RAG failure at 7 weeks after transplantation.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Dual photon absorptiometry is a reliable method of assessing bone mineral density. However, distortions of bony architecture, which may not be evident from the low-resolution images provided, can complicate the evaluation and lead to misleading findings. A case is presented which describes the importance of clinical and radiographic correlation.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Radionuclide and radiographic images of a case of condensing osteitis of the clavicle are presented. The clinical and radiographic features are discussed along with a differential diagnosis of sclerotic lesions of the clavicle.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Extensive skeletal involvement of multiple myeloma was detected by Ga-67 citrate imaging while searching for infectious foci. The case was unique in that a radiographic skeletal survey showed typical lytic lesions only in the skull, and extensive myeloma involvement in the skeletal system was an incidental finding. A high tumor cell burden was presumed to be present, which led to a rapid and fulminant clinical course in this patient.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

An analysis of hepatic imaging (liver-spleen scintigraphy, ultrasonography, and computed tomography) was performed in 91 patients prospectively referred for percutaneous liver biopsy for suspected chronic liver disease. Hepatic imaging was performed in 51 of 91 patients (56%). Of these 51 patients, 42 (82%) underwent radionuclide imaging, whereas only seven (14%) underwent ultrasonography and only two (4%) underwent computed tomography performed. Scintigraphy revealed evidence of diffuse liver disease in 40 of 42 patients (95%) vs 0 of 7 patients (0%) for ultrasonography (P < 0.0001). The frequency of imaging varied significantly by prebiopsy presumptive diagnosis, but this pattern was primarily a reflection of patient age. Imaging was performed in 76% of patients over 50 years of age vs 37% of patients below this age (P < 0.001). In the hospital, scintigraphy is still prominently used as a screening tool before referral for percutaneous liver biopsy. Justification of this use involves multiple reasons beyond simply a diagnosis.

ISSN:0363-9762    

出版商:OVID    

年代:1988

数据来源: OVID