摘要:

With the new myocardial agent Tc-99m sestamibi, relatively high abdominal uptake represents a major limiting factor. The effect of a standard feeding (commercial milkshake taken immediately after injection), and posture (standing versus sitting for 10 minutes postinjection) on the resting biodistribution of sestamibi was investigated in patients receiving 3 to 5 MBq/kg injections as part of rest-stress tomography. Ancillary anterior 1-minute images of heart and abdomen were obtained at 15 minutes postinjection and 90 to 140 minutes postinjection in 32 patients, randomized to feeding and postural treatments. Feeding decreased the activity in the gallbladder at both 15 and 110 minutes, but had no effect on liver parenchyma; activity in a background rectangle immediately beneath the heart was decreased by feeding only on the 15-minute images. An effect of posture was not apparent. Further study of the acute effects of a milkshake in eight patients showed a prompt reduction of 26% in a subdiaphragmatic background rectangle, but a more gradual decline in gallbladder counts. Thus, feeding of lipid after injection is not an essential component of sestamibi imaging protocols; oral administration of fluid immediately before imaging may help reduce interfering gastric activity.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Takayasu's disease (pulseless disease) is an uncommon chronic inflammatory disease primarily affecting the medium and large arteries, with a strong predilection for the aortic arch and its branches; hence, it sometimes is referred to as aortic arch syndrome. The etiology is unknown, although a systemic immunologic process seems most likely. About half the reported cases also revealed involvement of the pulmonary and renal arteries. The involvement is more marked in the origin of the vessel than distally. Although it is more common among Orientals, its distribution is worldwide, without racial boundary. A case is presented in which captopril renal scintigraphy and digital subtraction angiography were used to show renal artery stenosis as the cause of the patient's hypertension.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

A Tc-99m MAG3 renal scintigram was performed on a patient with severe renal insufficiency and bilateral ureteral stents. The Tc-99m MAG3 study displayed typical findings for renal insufficiency but also suggested the presence of lower tract obstruction. Moreover, the delayed posterior and posterior oblique views of the abdomen revealed an extrarenal collection of tracer suggestive of a urinary leak. With the help of additional views, this extrarenal activity was proven to be tracer in the bowel and biliary system. Biliary excretion of Tc-99m MAG3 can be prominent in patients with renal insufficiency and could lead to an erroneous diagnosis of urinary leak. Finally, scintigraphic diagnosis of lower tract obstruction may be difficult in patients with renal insufficiency, but some helpful signs may lead to the correct diagnosis.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Total body 1-131 scanning done on a 67-year-old woman with thyroid cancer revealed abnormal tracer uptake within the mid-thorax, thought to represent metastasis in the mediastinum or thoracic spine. Single-photon emission computed tomography images of the thorax showed contiguity between the thoracic uptake and the normal, physiologic uptake of radioiodine in the stomach, suggesting physiologic accumulation within a hiatal hernia. To confirm the alimentary tract location of the radioiodine, a study using orally administered Tc-99m SC in water was performed. The images were similar to the iodine images and revealed a pattern consistent with hiatal hernia. A hiatal hernia was also observed as an incidental finding on chest radiographs and an MRI. This case illustrates the potential for an abnormal anatomic configuration to mimic metastatic thyroid cancer and shows how SPECT and oral Tc-99m SC images may be useful in making this distinction.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Brain perfusion SPECT imaging using Tc-99m ethyl cysteinate dlmer (ECD) was carried out in 12 patients with chronic cerebrovascular disease. The sensitivity of lesion detection and lesion-to-normal tissue contrast was compared with those of I-123 IMP and Tc-99m HMPAO. Eight patients underwent all three studies and the remaining four patients had Tc-99m ECD and I-123 IMP scans. The sensitivity of lesion detection and lesion contrast was analyzed quantitatively using an asymmetric index determined by the equation: 100 x I |right - left| l/ (right + left). In the cerebral cortex, cerebellum, and white matter, I-123 IMP showed higher lesion sensitivity than Tc-99m ECD and Tc-99m HMPAO. In the striatum and thalamus, Tc-99m ECD and I-123 IMP showed higher lesion sensitivity than Tc-99m HMPAO. I-123 IMP showed the highest lesion contrast in cerebral cortex and cerebellum, whereas Tc-99m ECD showed the highest contrast in thalamus and striatum. In all regions, Tc-99m ECD showed higher lesion contrast than Tc-99m HMPAO. These results suggest regional variation in the sensitivity of lesion detection and lesion contrast of Tc- 99m ECD compared to I-123 IMP, and the superiority of Tc-99m ECD to Tc-99m HMPAO

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

The case of a patient with malignant fibrous histiocytoma is described. Emphasis is placed on the preoperative implementation of bone scintigraphy and MRI, which yielded discrepant findings. The ultimate therapeutic approach is discussed in light of the discrepancy and the conclusive pathologic result.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

A modification of standard lymphoscintigraphic imaging is described that incorporates the use of a two-headed camera with flood source to provide combined whole-body transmission–emission images of lymphatic drainage in a patient with malignant melanoma. The most common imaging technique for lymphoscintigraphy uses single-head gamma cameras with or without skin markers. The authors performed both techniques on their patient, and believe that the modification may provide a clearer image for lymphoscintigraphic interpretation.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Five cases of artifactual In-111 leukocyte pulmonary activity were noted at three local hospitals in a 4-day period. Based on the differences in the preparation of the final indium leukocyte product, the problem could be attributed to the indium oxine reagent in a specific lot. This artifact of multiple small foci of marked increased activity in the lungs (clumping pattern), attributable to the In-111 oxine reagent, has not been described previously.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

Neonatal seizures can be difficult to classify according to partial versus generalized onset on the basis of clinical appearance or electroencephalography (EEG). Single-photon emission computed tomography has proven to be useful in adults when adjunctive tests are needed to identify the nature of seizure onset. Although its use has been extended recently to children, the lower age limit at which this technique is useful remains to be established. A case is reported in which ictal Tc-99m HMPAO SPECT of a 16-day-old infant revealed an area of MRI. The EEG of this infant demonstrated multifocal interictal epileptiform abnormalities and an ictal pattern with generalized onset. This case indicates that ictal SPECT is a useful tool in the evaluation of even the youngest patients with seizures.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID

摘要:

To evaluate treatment efficacy, TI-201 SPECT was performed in three patients with pancreatic cancer. In all of the patients, the degree of TI-201 uptake by tumor, evaluated from the tumor-liver uptake ratio of TI-201 activity, correlated well with alterations in serum level of a tumor marker (CA 19-9, DUPAN-2) after treatment. One of the patients showed no tumor shrinkage on CT after treatment; however, TI-201 SPECT demonstrated reduced uptake in the tumor coupled with a decreased level of CA 19-9. These results suggest that TI-201 SPECT may become a new tool for assessing the efficacy of treatment in pancreatic cancer.

ISSN:0363-9762    

出版商:OVID    

年代:1993

数据来源: OVID