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1. |
Image Normalization and Background Subtraction in TI-201 /Tc-99m Parathyroid Subtraction Scintigraphy Effect on Lesion Detection |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 81-89
WILLIAM ERWIN,
MARK GROCH,
AMJAD ALI,
ERNEST FORDHAM,
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摘要:
The authors have developed two computer algorithms for TI-201/Tc-99m parathyroid subtraction scintigraphy that was performed on patients who subsequently underwent surgical exploration of the neck. Both methods employed a region-of-interest drawn around the thyroid/parathyroid glands for image realignment. The first algorithm normalized the TI-201 and Tc-99m images using the ratio of maximum counts over the thyroid in each image. The second computer algorithm incorporated TI-201 image background correction and normalization by the average of the ratios of maximum counts computed over each quadrant in both images. In 10 patients with confirmed parathyroid adenomas or hyperplasia, the first method yielded a 44% sensitivity. Upon reanalysis with the second algorithm, the sensitivity improved to 100%. Subsequently, in a total of 22 patients with 30 abnormal glands analyzed with the second algorithm, a sensitivity of 80% (94% for adenoma and 62% for hyperplasia) was achieved, with a specificity of 91%, as confirmed by surgery.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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2. |
Aerosol Scintigraphy in the Assessment of Therapy for Cystic Fibrosis |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 90-93
C C KUNI,
W E REGELMANN,
R P duCRET,
R J BOUDREAU,
J R BUDD,
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摘要:
Thirteen patients with cystic fibrosis (aged 11 to 32 years) who were hospitalized for exacerbation and who had sputum cultures positive for Pseudomonas organisms were treated initially for 4 days with bronchodilators and physiotherapy followed by the addition of antibiotic (14 days, n = 8) or placebo (14 days, n = 4; 7 days, n = 1). Tc-99m DTPA aerosol scintigraphy was performed on the day before bronchodilators and physiotherapy, on the day before antibiotic or placebo, and on the day after completion of antibiotic or placebo therapy. Scintigrams were evaluated for change in the number of nonventilated segments and change in the number of bronchial deposits of aerosol. Sixty-nine percent of patients showed improvement after bronchodilators and physiotherapy alone. Sixty-two percent showed further improvement after antibiotic or placebo was added; this improvement was independent of whether antibiotic or placebo was administered (P > 0.1). These aerosol scintigraphy results failed to demonstrate that the effectiveness of bronchodilators and physiotherapy is enhanced by antibiotics in the treatment of cystic fibrosis exacerbations.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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3. |
Ventilation-Perfusion Lung Imaging in Nitrofurantoin-related Pulmonary Reaction |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 94-96
NORMAN LEE,
JAMES SLAVIN,
RICHARD SPENCER,
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摘要:
A woman with a history of multiple drug allergies was admitted for cough and dyspnea. She had been taking nitrofurantoin for 10 days, was febrile, and had a rash on the trunk and extremities. A chest radiograph revealed right-sided pleural effusion and basal markings. Because of suspected nitrofurantoin-related pulmonary reaction, the medication was discontinued and the patient was started on an H2-blocker and intravenous corticosteroids. She improved clinically, and within 24 hours a radiograph revealed that her chest had largely cleared. Restricted distribution of radioxenon, seen initially on a ventilation lung scan, also reverted to near normal by the follow-up. The first perfusion lung scan showed multiple but nonspecific changes; this also came back to near normal. The nitrofurantoin-related pulmonary reaction should be considered in patients who present with pulmonary signs/symptoms while on the medication.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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4. |
Ga-67 Uptake Unsuppressed by Leukopenia and Intense Antibiotic Therapy |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 97-98
MIGUEL GORENBERG,
DAVID GROSHAR,
EINAT EVEN-SAPIR,
SIMONA BEN-HAIM,
ORA ISRAEL,
DOV FRONT,
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摘要:
The authors describe a patient with myelofibrosis who showed intense Ga-67 uptake in spite of being severely leukopenic and receiving large amounts of antibiotics. They conclude that false-negative results associated with leukopenia or intensive antibiotic treatment may not always be correct.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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5. |
Splenic Metastasis of Hepatocellular Carcinoma Accumulation of Tc-99m HDP |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 99-100
HAJIME FUJIMOTO,
KOJI MURAKAMI,
KENJI NOSAKA,
NOBORU ARIMIZU,
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摘要:
Considerable accumulation of Tc-99m HMDP was noted in a huge splenic mass in a 62-year-old man with hepatocellular carcinoma. An autopsy revealed a massive hemorrhage within the splenic metastasis. The splenic uptake of the radionuclide corresponded to the marked deposition of hemosiderin.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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6. |
Tc-99m PYP Imaging in Amphetamine Intoxication Associated with Nontraumatic Rhabdomyolysis |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 101-102
CHIA-HUNG KAO,
SHU-QUINN LIAO,
SHYH-JEN WANG,
SHIN-HWA YEH,
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摘要:
Nontraumatic rhabdomyolysis was demonstrated by Tc-99m PYP muscle imaging in a case of amphetamine intoxication.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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7. |
Ga-67 Citrate in Diagnosing Tracheoesophageal Fistula in a Patient with AIDS Case Report |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 103-105
CAROLINE CHOW,
EDUARD KOTLYAROV,
GEORGE FANTRY,
LISA PICHNEY,
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摘要:
Increased radiopharmaceutical uptake in the mediastinum and/ or hilum on Ga-67 citrate scan in patients with AIDS has been attributed, to date, mostly to infectious etiologies. Because other complications are being reported in these patients, awareness of their presentation in diagnostic imaging is important. Tracheoesophageal fistula can also be accompanied by a focal area of increased uptake in the mediastinum. In this patient, a Ga-67 citrate scan was the first modality of diagnostic imaging to raise suspicion of such a diagnosis.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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8. |
Value of Three-dimensional Surface Display of Brain Perfusion ImagingComparison with Tomographic Imaging |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 106-109
NORINARI HONDA,
KIKUO MACHIDA,
TOSHIO MAMIYA,
TAKU TAKAHASII,
TERUO TAKISHIMA,
TSUYOSHI KAMANO,
SATOSHI TAMAKI,
MASAYUKI MURAMATSU,
RYUICHI BAN,
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摘要:
The diagnostic ability of a three-dimensional surface display of 1-123 IMP brain scintigrams and tomographic images was compared in 12 patients who underwent 1-123 brain tomography for cerebral cortical hypoperfusion. Foci of decreased accumulation were independently diagnosed by four radiologists, first with transaxial images, second with three-dimensional images, and finally with both images subjectively compared for the purpose of diagnosing the existence, localization, and extent of lesions. Six different lesions (0 to 3 lesions/radiologist) were found only on the transaxial images, but 30 different lesions (1 to 14 lesions/radiologist) were found on the three-dimensional images. In 9 out of 12 cases, the threedimensional images were regarded as superior for evaluating the extension of the lesion and for lesion existence and lesion localization in 5 out of 12 (P < 0.05). In conclusion, a three-dimensional display of an 1-123 IMP brain tomogram is superior to tomographic images in diagnosing the extent of cerebral cortical hypoperfusion. However, the display is not superior to tomographic images for diagnosing the existence and localization of hypoperfusion.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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9. |
Scintigraphic Analysis of Hemodynamics in a Patient with a Single Large Pulmonary Arteriovenous Fistula |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 110-113
KAZUYOSHI SUGA,
TATSUYA KURAMITSU,
TAZUKO YOSHIMIZU,
TAKASHI NAKANISHI,
NORIMASA YAMADA,
HIROMOTO UTSMI,
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摘要:
A pulmonary perfusion study was performed on a 54- year-old man with a single large pulmonary arteriovenous fistula (aneurysmal type) using Tc-99m MAA. On the static imaging, a defect corresponding to the location of the mass and right-to-left shunt was clearly documented. Decreased uptake of Tc-99m MAA in the lung field surrounding the lesion was observed and was thought to reflect a “steal” of blood flow by the fistula. One advantage of using radionuclide angiography with Tc-99m MAA rather than with Tc-99m pertechnetate was that it more easily provided a time-activity curve that added useful quantitative information about the altered pulmonary hemodynamics.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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10. |
Multiple Metastatic Calcifications Detected by Bone Scintigraphy and Demonstrated by CT |
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Clinical Nuclear Medicine,
Volume 17,
Issue 2,
1992,
Page 114-118
YOSHIMASA IMANISHI,
MASAKI KISHIRO,
OSAMU MIYAZAKI,
TATSUKI TOYOKAWA,
KAZUNORI KUROKI,
HITOSHI HAJI,
TOHRU ISHIKAWA,
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摘要:
Metastatic calcifications according to histopathologic and scintigraphic findings have been well-defined. The authors report a postoperative case of hyperparathyroidism with multiple metastatic calcifications in the lung, kidney, stomach, heart, and vessels that were primarily detected by bone scintigraphy and demonstrated by CT. Tc-99m MDP bone scintigraphy showed a markedly increased accumulation of radioactivity diffusely throughout the lung, left ventricular wall, both kidneys, and the gastric cardia and body. In the lung, plain films showed almost normal lung. CT, however, demonstrated patchy, slightly increased densities in the lung bilaterally. Cardiac CT indicated a considerably increased density of the ventricular myocardium and remarkable calcification in or near the atrioventricular septum or annulus fibrosus. Upper abdominal CT demonstrated increased densities diffusely throughout the gastric mucosa and renal cortex. Only vascular calcifications were depicted by plain films. Using both bone scintigraphy and CT provides accurate information about each lesion and each tissue, allowing precise diagnosis of even a questionable lesion in the early stage of metastatic calcification. Early diagnosis and early therapy offer the best chance for cure or palliative therapy.
ISSN:0363-9762
出版商:OVID
年代:1992
数据来源: OVID
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