摘要:

In a pilot survey to compare the relative prevalence of three diseases in apparently healthy White Fulani Zebu (WFZ) cattle slaughtered in Nigeria, sera from 80 randomly selected animals with no significant gross lesions on ante mortem and post mortem inspection were examined for antibodies toBrucella abortus, Dermatophilus congolensisand bovine leukaemia virus.

ISSN:0165-2176    

DOI:10.1080/01652176.1987.9694080

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

In contrast with the recommended dose of 2,000 drinking ppm sulphadimidine sodium in the water for treatment of broilers against colibacillosis,it appeared that under experimental conditions, treatment at 500 ppm (60 mg/kg body weight) gave the best therapeutic effects. At higher concentrations, drinking water consumption and body weight gain were reduced significantly. During treatment high blood plasma‐concentrations were measured.

ISSN:0165-2176    

DOI:10.1080/01652176.1987.9694081

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

The snailCepaea hortensiscan acetylate and hydroxylate sulphatroxazole via a pathway similar to that in man. The principal metabolic pathways, in order of decreasing rate, are hydroxylation, glucuronidation and acetylation. The slugAnion rufusalso can acetylate and hydroxylate sulphatroxazole, although, in contrast to the snail, is rate of acetylation is higher than that of hydroxylation.

ISSN:0165-2176    

DOI:10.1080/01652176.1987.9694082

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

摘要:

The present investigation was undertaken to improve regimens dosage of amoxycillin, chloramphenicol or trimethoprim‐sulphadiazine in Salmonella dublin infected veal calves. The pharmacokinetics of these drugs were studied after i.v., oral, and i. m. administration (bioavailability, local irritation at the injection site, volume of distribution, and elimination half life). The most important conclusion was that amoxycillin, chloramphenicol, and trimethoprim were suitable for oral administration to veal calves, although the bioavailability of chloramphenicol and trimethoprim was significantly less when concurrently administered with a milk replacer. In vitro, the antibacterial activities of these drugs were compared. Addition of trimethoprim to sulphadiazine lowered its MIC forS. dublin, but sulphadiazine reduced the killing rate compared to that of trimethoprim alone. In the efficacy studies the activities of several serum enzymes and the plasma concentrations of Fe, Zn, and Cu were measured, but it appeared, that these biochemical parameters were no better than the clinical parameters body temperature and body weight. Using optimal dosage regimens based on MIC values and blood levels, treatment with either of the three drugs was of equal efficacy.

ISSN:0165-2176    

DOI:10.1080/01652176.1987.9694083

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor

ISSN:0165-2176    

DOI:10.1080/01652176.1987.9694069

出版商:Taylor & Francis Group    

年代:1987

数据来源: Taylor