摘要:

In two dogs with pituitary‐dependent hyperadrenocorticism, adrenocorticolysis with o,p'‐DDD led to the disappearance of the signs and symptoms except for the polyuria. After a modified water‐deprivation test the osmoregulation of vasopressin release was studied by hypertonic saline infusion. In both dogs the hypertonicity, thus induced, resulted in very minimal responses of the vasopressin secretion.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694223

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

Cyclic heifers were implanted with the synthetic androgen trenbolone acetate (TBA = 17 beta‐hydroxy‐19‐norandrosta‐4, 9, I tries 3 ors beta‐acetate, C20H2403) (for formulas see Fig. 1). The influence of this androgen on the macroscopic and microscopic morphology of the genital tract was studied.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694224

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

The efficacy of the oxfendazole pulse release bolus (OPRB) was tested in a grazing experiment at the University of Utrecht. Three groups of four OPRB‐treated calves and one group of four untreated control calves were grazed on separate pastures between 18 May and 21 October 1987. Based on faecal egg counts for strongyle‐type eggs andNematodiruseggs, embryonation ofNematodiruseggs and faecal larval counts for lungworm, the first pulse of oxfendazole was released after 28 to 63 days, which was later than the period of approximately three weeks indicated by the manufacturer and others. As far as could be detected, the second to fifth pulses were not as delayed, but generally the three‐week period was also exceeded.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694225

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

In six experiments 43 castrated male conventional pigs weighing 25 – 41 kg were catheterised by inserting a cannula via the jugular vein into the cranal caval vein. The catheters were taped to the spinal neck region where the tap stops were located. Antimicrobial agents were not applied.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694226

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694227

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

The results of the cytological and histological examination of 348 canine lesions, localised in various organs, were compared with respect to the tumourous or non‐tumour nature of the lesions and the malignancy or benignancy of tumours. The retrieval rate was 92.5%. Regarding the distinction between tumourous and non‐tumourous lesions, the cytological examination showed a diagnostic accuracy of 83.9%, a sensitivity of 95.6%, a specificity of 65.4% and a predictive value for the presence of tumour of 93.5%. The diagnostic accuracy of cytology concerning the differentiation in malignancy and benignancy of the neoplasms was 83.7%, with a sensitivity of 86.8%, a specificity of 79.4% and a predictive value for the presence of malignant tumour of 85.6%. These results confirm the value of non‐exfoliative cytology as a diagnostic method, providing rapid and valuable information with regard to diagnosis and prognosis and, consequently, for therapeutic handling. An eventual histological diagnosis remains indicated, especially in case of soft‐tissue and mammary lesions.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694228

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

The oral absorption and bioavailability of flumequine was studied in 1‐, 5‐ and 18‐week‐old calves following intravenous and oral administration of different formulations of flumequine (Flumix®, Flumix C®and pure flumequine). Increasing age had a negative influence on the Cmaxafter the administration of Flumix®, based on a larger VDin the older calves. The Cmaxdecreased from 5.02 ± 1.46 μg/ml in the first week to 3.28 ± 0.42 μg/ml in the 18th week. Adding colistin sulfate to the flumequine formulation and administring pure flumequine mixed with milk replacer had a negative effect on the Cmaxof flumequine after oral administration of 5 and 10 mg/kg body weight. The bioavailability of the orally administered flumequine formulations was 100% in all cases except after the administration of Flumix C®, for which it was 75.9 ± 18.2%. The urinary recovery of flumequine after intravenous injection of a 10% solution varied from 35.2 ± 2.3% for Group B. to 41.2 ± 6.3% for Group C.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694229

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

The time courses of the total (Ct) and unbound plasma (Cf) concentration after the i.v. injection of 20, 50 and 100 mg/kg of sulphadimethoxine (SDM) were examined in pigs;

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694230

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

A severe outbreak of respiratory tract disease associated with bovine respiratory syncytial virus (BRSV) on a large beef‐fattening farm is described. The outbreak started two days after five‐ to seven‐month‐old calves were vaccinated with a modified live BRSV vaccine. The disease ran a very severe course among five‐ to seven‐month‐old vaccinated calves, but disease was absent in eight‐month‐old an older non‐vaccinated calves. The presence of IgM antibodies in sera of non‐vaccinated calves indicated that BRSV was spreading on the farm between two to 15 days before the day of vaccination. The data indicate that vaccination with modified live vaccine during the course of a natural infection may enhance the severity of disease. The possible pathogenesis of the disease is discussed.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694231

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor

摘要:

To determine whether prolactin has luteolytic properties during the first part of the luteal period, hysterectomy was performed in four dogs, in which prolactin had been chronically suppressed by bromocriptine administration. The concentration of progesterone in the peripheral blood decreased upon hysterectomy during the first part of the luteal phase and regained normal values after about seven days. The progesterone patterns during the perisurgical period in these dogs were similar to those patterns observed in dogs hysterectomised without bromocriptine treatment. It is concluded therefore that, in the dog, luteolytic properties can not be attributed to prolactin.

ISSN:0165-2176    

DOI:10.1080/01652176.1989.9694232

出版商:Taylor & Francis Group    

年代:1989

数据来源: Taylor