摘要:

Cerebrospinal fluid (CSF) was allowed to drop straight into Hanks's balanced salt solution. After centrifugation the pellet was resuspended and mixed with sheep erythrocytes. The mixture was further handled as in the E‐rosette test with peripheral blood lymphocytes. CSF from 20 individuals were investigated, and rosette‐forming cells (RFC) were found in all. Six patients with normal fluid had between 46% and 83% RFC. Four patients with multiple sclerosis had increased numbers of RFC (94%–96%). Low numbers of RFC were found in one patient with cerebellar ataxia and in one of two patients with acute viral meningitis. With this technique RFC can be counted even in normal CSF with a 3‐ml

ISSN:0300-9475    

DOI:10.1111/j.1365-3083.1976.tb03004.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Amyloid‐related serum protein (SAA) was studied with a double immunodiffusion method. Only 2 of 21 patients with inherited systemic amyloidosis and lattice corneal dystrophy had elevated SAA levels in their sera. Several pseudo‐exfoliation patients had elevated levels of SAA, but it was not possible to differentiate an age‐related elevation of SAA from that associated with this disease. In addition, SAA was found in the sera of many groups of patients with acute viral infections, including 10 of 11 patients with measles and 7 of 11 persons vaccinated against rubella. Elevation of SAA protein appeared in the serum before the 6th day after the vaccination, had its peak value between days 6 and 12, but was absent already on the 20th day. In this relation the SAA protein appears to behave as an acute‐phase r

ISSN:0300-9475    

DOI:10.1111/j.1365-3083.1976.tb03005.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

ISSN:0300-9475    

DOI:10.1111/j.1365-3083.1976.tb03006.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY