|
11. |
The Sites of Action of Ovarian Steroids in the Regulation of LH Secretion |
|
Neuroendocrinology,
Volume 32,
Issue 1,
1981,
Page 57-63
R.L. Goodman,
E. Knobil,
Preview
|
PDF (1562KB)
|
|
摘要:
In the monkey, estradiol appears to exert both its negative and positive feedback actions on gonadotropin secretion primarly at the hypophysial level. In the rat, inhibitory and stimulatory effects of estradiol on the pituitary are also evident, but additional actions on the medial basal hypothalamus (MBH) and preoptic area must be postulated to fully account for the negative and positive feedback effects of estradiol in this species. The available evidence points to the MBH as a site for the negative feedback action of progesterone in the rat. In both species, progesterone probably acts in the central nervous system to block the positive feedback action of estradiol while the facilitation of luteinizing hormone release by this steroid appears to be at a hypophyisial level.
ISSN:0028-3835
DOI:10.1159/000123130
出版商:S. Karger AG
年代:1981
数据来源: Karger
|
12. |
Announcements |
|
Neuroendocrinology,
Volume 32,
Issue 1,
1981,
Page 64-64
Preview
|
PDF (113KB)
|
|
ISSN:0028-3835
DOI:10.1159/000123131
出版商:S. Karger AG
年代:1981
数据来源: Karger
|
|