摘要:

Abstract —As the etiology of maxillonasal dysplasia (Binder's syndrome) is unclear, an attempt has been made in this study to check the presence of hereditary factors. Pedigrees have been established for 50 patients with the syndrome who had actively requested orthodontic treatment and/or plastic surgery and for whom hereditary connections had been found in 36%. In some of the subjects the propositi volunteered further family data, which were included in the study. The total number thereby became 60 families. The results did not disprove the possibility of a genetic etiology although the suspicion of an autosomal recessive inheritance may not be the full explanation for the syndrome. If the syndrome is in fact of a genetic origin, one possibility is that the syndrome is indeed inherited as an autosomal recessive trait. In that case, the hypothesis of an incomplete penetrance must be added. Another possibility is that the syndrome is a threshold character with a genetically multifactorial background. Since no frequency counts among populations are available, further studies are required to collect families with maxillonasal dysplasia and to obtain population frequency data for the syndrom

ISSN:0909-8836    

DOI:10.1111/j.1600-0722.1988.tb01410.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Abstract —The marginal degradation and corrosion of restorations made of a high copper dispersed amalgam were studied as a function of time for up to 5‐yr observation periods. The effect of minor defects present after finishing the restorations was included in the assessment of the initial marginal degradation. A slow progressive marginal degradation was noted and it was enhanced by initial defects. Subsurface corrosion including attacks of the phase and grain boundaries, corrosion within the bulk, and layers of corrosion products along the tooth/restoration interfaces were observed in restorations after some years in clinical service. The subsurface corrosion is considered to weaken the amalgam and it might enhance the marginal degradation, i.e. a stress corrosion type of degradat

ISSN:0909-8836    

DOI:10.1111/j.1600-0722.1988.tb01411.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY