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21. |
Sympathetic Contribution to the Cardiac Response to Stress in Hypertension |
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Hypertension,
Volume 5,
Issue 1,
1983,
Page 147-154
CARLO ALICANDRI,
FETNAT FOUAD,
ROBERT TARAZI,
EMMANUEL BRAVO,
RICHARD GREENSTREET,
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摘要:
Studies of cardiac performance in hypertension have often been restricted to cardiac output determinations, although the latter alone are inadequate for that purpose. To define the range of cardiac performance in hypertension, the response of left ventricular filling pressure to increased workload (static exercise) was determined in 39 subjects — eight normotensive (NT) volunteers, seven patients with borderline hypertension (BLH), and 24 essential hypertensives (EH), of age-matched groups. A rise of mean pulmonary wedge pressure (PWP) by 5 mm Hg or more during maximum handgrip (HG) was considered “abnormal” for a workload (SBP × HR × 10−3) increase of ⩾ 25%. All NT subjects and all patients with BLH as well as 16 of the 24 EH (EH-I) showed normal cardiac performance by this definition. In contrast, PWP increased ⩾ 5 mm Hg during HG in eight patients with EH (EH-II). The calculated increase in cardiac workload was not significantly different among the four groups ( + 5, 5.8, 5.4 and 5.5 respectively). Beta blockade (propranolol, 10 mg i.v.) slowed heart rate in all subjects and reduced SBP × HR product in all groups both at rest and during HG. Responses of PWP to HG were widely divergent in the different patients. However, as a group those patients with “impaired cardiac performance” before propranolol (EH-II) had a greater reduction in performance following propranolol than EH-I or NT. This study suggests that adrenergic support of cardiac performance might be important in some hypertensive patients with no evidence of heart failure.
ISSN:0194-911X
出版商:OVID
年代:1983
数据来源: OVID
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22. |
Dopaminergic Control of Prolactin and Blood Pressure |
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Hypertension,
Volume 5,
Issue 1,
1983,
Page 155-156
JAMES SOWERS,
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ISSN:0194-911X
出版商:OVID
年代:1983
数据来源: OVID
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23. |
The Age Factor and Salt‐Induced Hypertension in the Brattleboro Rat |
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Hypertension,
Volume 5,
Issue 1,
1983,
Page 156-157
JOSEF ZICHA,
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ISSN:0194-911X
出版商:OVID
年代:1983
数据来源: OVID
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24. |
News from the American Heart Association |
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Hypertension,
Volume 5,
Issue 1,
1983,
Page 158-163
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PDF (437KB)
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ISSN:0194-911X
出版商:OVID
年代:1983
数据来源: OVID
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