|
1. |
Is It Essential to Change the Term “Essential Hypertension”? |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 7-7
Barry Materson,
Preview
|
PDF (30KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
2. |
Correction |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 8-8
&NA; &NA;,
Preview
|
PDF (17KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
3. |
Correction |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 9-9
&NA; &NA;,
Preview
|
PDF (19KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
4. |
Pathophysiology of Hypertensive Renal DamageImplications for Therapy |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 595-601
Anil Bidani,
Karen Griffin,
Preview
|
PDF (231KB)
|
|
摘要:
Unlike the majority of patients with uncomplicated hypertension in whom minimal renal damage develops in the absence of severe blood pressure (BP) elevations, patients with diabetic and nondiabetic chronic kidney disease (CKD) exhibit an increased vulnerability to even moderate BP elevations. Investigations in experimental animal models have revealed that this enhanced susceptibility is a consequence of an impairment of the renal autoregulatory mechanisms that normally attenuate the transmission of elevated systemic pressures to the glomeruli in uncomplicated hypertension. The markedly lower BP threshold for renal damage and the steeper slope of relationship between BP and renal damage in such states necessitates that BP be lowered into the normotensive range to prevent progressive renal damage. When BP is accurately measured using radiotelemetry in animal models, the renal protection provided by renin-angiotensin system (RAS) blockade is proportional to the BP reduction with little evidence of BP-independent protection. A critical evaluation of the clinical data also suggests that the BP-independent renoprotection by RAS blockade has been overemphasized and that achieving lower BP targets is more important than the selection of antihypertensive regimens. However, achievement of such BP goals is difficult in CKD patients without aggressive diuresis, because of their proclivity for salt retention. The effectiveness of RAS blockers in lowering BP in patients who have been adequately treated with diuretics, along with their potassium-sparing and magnesium-sparing effects, provides a more compelling rationale for the use of RAS blockade in the treatment of CKD patients than any putative BP-independent renoprotective superiority.
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
5. |
Measuring Adherence to Practice Guidelines for the Management of HypertensionAn Evaluation of the Literature |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 602-608
Jessica Milchak,
Barry Carter,
Paul James,
Gail Ardery,
Preview
|
PDF (72KB)
|
|
摘要:
Adherence to practice guidelines is frequently used as a measure of quality of care. Numerous studies have evaluated physician adherence to hypertension guidelines by prescription data, physician survey data, or medical record review. However, most have methodological limitations that might underestimate physician adherence. Accurate and meaningful characterization of adherence rests on evaluation of varied components of hypertension care, use of explicit validated performance measures, incorporation of implicit and explicit review, and linkage of process measures to blood pressure outcomes.
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
6. |
More on the Sodium Saga |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 609-611
Myron Weinberger,
Preview
|
PDF (47KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
7. |
Cognitive Impairment and Blood PressureQuo Usque Tandem Abutere Patientia Nostra? |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 612-613
Jan Staessen,
Willem Birkenhäger,
Preview
|
PDF (40KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
8. |
Importance of Achieving Lower Blood Pressure in Hypertensive Patients With Diabetes |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 614-615
Charles Brooks,
James Sowers,
Preview
|
PDF (33KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
9. |
Sensing TensionRecognizing ENaC as a Stretch Sensor |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 616-617
Dale Benos,
Preview
|
PDF (41KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
10. |
An Emerging Role for Adenosine in Angiogenesis |
|
Hypertension,
Volume 44,
Issue 5,
2004,
Page 618-620
Thomas Adair,
Preview
|
PDF (43KB)
|
|
ISSN:0194-911X
出版商:OVID
年代:2004
数据来源: OVID
|
|