摘要:

ABSTRACTCellular and subcellular changes and cell‐mediated immunity of a patient (a 26‐year‐old man) with spontaneously regressed malignant melanoma are described.The patient developed black nodules on his left leg and foot several times over a period of 11 years. These nodules necrotized, regressed to form crusted nodules and disappeared leaving white macules.Many melanin‐laden cells (so‐called melanophages) were seen in the upper dermis of the melanotic macules, and no melanoma cells were observed in the upper dermis of the white macules which appeared at the site of regressed melanotic macules or nodules.In melanin‐laden cells observed in melanotic macules, many melanosome complexes with hydrolytic enzyme activity and a small number of single melanosomes were recognized. We assumed that some or many of the melanin‐laden, melanophage‐like cells in the upper dermis of a regressing malignant melanoma might be effete melanoma cells. Cell‐mediated immunity had been preserved while spontaneous regression of tumors was occurring.However, the patient died as a result of metastatic melanomas which involved the lymph nodes, liver, bones, brain, heart, kidney, lung and gastr

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1981.tb02014.x

年代:1981

数据来源: WILEY

摘要:

ABSTRACTThe types of earwax which may manifest characteristics of the skin surface, were found to be related with the incidence of tinea versicolor caused by lipophilic fungus,Malassezia furfur. The condition of earwax is usually classified into 2 types, wet and dry. Of 223 Japanese cases of tinea versicolor examined in Kumamoto, wet earwax was found in 90 cases (40.9%). The results indicate a statistically significant higher incidence than in normal Japanese, among which the percentage of individuals with wet earwax is 16%.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1981.tb02015.x

年代:1981

数据来源: WILEY

摘要:

ABSTRACTThe results of mating experiments with isolates ofMicrosporum canisisolated in Japan were reported. Of the 120 cultures ofM. canisstudied, 111 originated from human cases and 9 from pet cats. Ninety‐eight of the isolates were compatible withNannizzia otaeand proved to be of the “—” mating type. Cleistothecia were not produced by 22 isolates in combination with the two compatible tester

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1981.tb02016.x

年代:1981

数据来源: WILEY

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1981.tb02017.x

年代:1981

数据来源: WILEY