摘要:

AbstractA 70‐year‐old man with a 2‐year history of annular elastolytic giant cell granuloma associated with diabetes mellitus was reported. The lesions mainly developed in non‐sun‐exposed areas. Histologic examination revealed phagocytosis of elastic fibers by histiocytic cells. Immunoperoxidase staining for lysozyme disclosed positive reactivity within the cytoplasm of these histiocytic cells. Electron microscopic study also showed elastic fibers and numerous lipid‐like substances in the cytoplasm of these cells. These findings indicate high phagocytolytic activity by these infiltrating cells. In our case, actinic damage was not considered to be a primary causative factor, and a possible pathogenesis was als

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb02996.x

年代:1987

数据来源: WILEY

摘要:

AbstractPsoriasis is a common inflammatory skin disease, but its pathogenesis is unknown. This paper presents 2 cases of psoriasis vulgaris in which the skin lesions were improved for 3 months and more after the start of oral treatment with 1α,25‐dihydroxyvitamin D3at a dose of 0.5 μg/day. The circulating levels of calcium, inorganic phosphate, 25‐hydroxyvitamin D, 1α,25‐dihydroxyvitamin D, parathyroid hormone and calcitonin were within normal ranges before and after the start of treatment. These findings suggest that 1α,25‐dihydroxyvitamin D3has a beneficial effect on psoriatic skin lesions. It probably has a direct effect on enhancing epidermal cell differentiation.Abbreviations:Ca: calcium, hCT: calcitonin, 25‐OHD: 25‐hydroxyvitamin D, 1,25‐(OH)2D: 1α,25‐dihydroxyvitamin D, 1,25‐(OH)2D3: 1α,25‐dihydroxyvitamin D

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb02997.x

年代:1987

数据来源: WILEY

摘要:

AbstractA case of papulonecrotic tuberculid showing widespread cutaneous eruptions is reported.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb02998.x

年代:1987

数据来源: WILEY

摘要:

AbstractGeneralized granuloma annulare commonly occurs in older adults. Atypical (perforating) forms are well known, but treatment can sometimes be complicated. A case of atypical generalized granuloma annulare successfully treated with PUVA is reported. The histology and immunohistology of the skin, histopathologic, immunohistopathologic and electronmicroscopic studies of the liver, immunoserology and laboratory investigations are detailed. The most important findings were as follows; diabetic glucose tolerance test, typical histology of the skin disease, steatosis and non‐specific reactive hepatitis, focal Kupffer cell proliferation, Kupffer cell autoantibodies in the liver and slightly enhanced liver functions. The hepatic lesions observed and latent diabetes mellitus are considered to be correlated with the generalized dermal symptom

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb02999.x

年代:1987

数据来源: WILEY

摘要:

AbstractA case of reactive perforating collagenosis (RPC) is presented. The lesions appeared in a female at the age of 4 years. So far, the patient has had only two episodes of RPC and both were precipitated by cold weather. The lesions showed the Koebner phenomenon. Histological sections showed the changes of “transepidermal elimination of necrobiotic connective tissue

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb03000.x

年代:1987

数据来源: WILEY

摘要:

AbstractIn this paper, we describe a 69‐year‐old Japanese woman with localized pemphigoid. Direct immunofluorescence study showed linear IgG, IgA and C3 deposits at the basement membrane zone (BMZ). In the serum, circulating anti‐BMZ antibodies of both IgG and IgA classes were found. This is the first report of a patient with localized pemphigoid in whom circulating anti‐BMZ antibodies of not only the IgG class, but also of the IgA class were

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb03001.x

年代:1987

数据来源: WILEY

摘要:

AbstractWe treated a patient with facial granuloma caused byTrichosporon cutaneum, in whom various therapeutic modalities had been ineffective. A surgical procedure combining excision, topical chemotherapy of the open wound, and covering the defect with a cervicofacial flap was finally successful.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb03002.x

年代:1987

数据来源: WILEY

摘要:

AbstractA tumor on the face showing follicular and apocrine differentiation is described. The coexistence of the two features suggests that the hair follicle has the potential to develop an apocrine gland tumor.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb03003.x

年代:1987

数据来源: WILEY

摘要:

AbstractA 13‐month‐old male infant with primary osteoma cutis was reported. There was no diagnostic sign of Albright's hereditary osteodystrophy in either this patient or his family. Laboratory investigations showed no abnormalities except moderate obesity (kaup index=

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb03004.x

年代:1987

数据来源: WILEY

摘要:

AbstractSolitary angiokeratoma was observed on the right leg of a 50‐year‐old Japanese female. In her childhood, she had repeatedly developed vesicles on the legs, and a possible diagnosis of pretibial epidermolysis bullosa was made, based on additional findings. Clinically, the condition resembled malignant melanoma and basal cell epithelioma. Possibly repeated injuries predisposed her to the development of solitary angiokerat

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1987.tb03005.x

年代:1987

数据来源: WILEY