摘要:

ABSTRACTPatients with staphylococcal infection of the skin were examined for immunological status. All cases examined in the present study had γ‐globulin levels within the normal range. The proliferative response of peripheral blood lymphocytes to staphylococcal antigen was significantly depressed in patients with furunculosis as compared with that in patients with common furuncle or in healthy controls. All patients with furunculosis showed higher titers of anti‐Staphylococcus aureusantibody than did those with furuncle. The dissociation between cellular and humoral immunity in furunculosis seems to be explained in terms of immune devia

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01024.x

年代:1977

数据来源: WILEY

摘要:

ABSTRACTThe lesions of herpes zoster in three patients were investigated electron microscopically before and after topical application of interferon.In the blister, on the 5th to 7th day after its formation, the following were seen: acantholytic cells with virus particles in the nucleus and cytoplasm, multinucleated cells derived from keratinocytes, edematous and degenerated keratinocytes containing virus particles and tonofibrillar materials, macrophages with many large vacuoles, neutrophils, lymphocytes and Langerhans's cells.After the first application of interferon, the findings for keratinocytes were the same as those of before application and keratinocytes were frequently found adjacent to macrophages. The macrophages were large and had numerons large vacuoles in the cytoplasm. After the second application of interferon, virus particles were often seen in the vacuoles of the macrophages in comparison with that before application. In the cytoplasm of macrophages, acantholytic keratinocytes and tonofibrillar materials were phagocytized. Many virus particles were seen in the vacuoles of some acantholytic keratinocytes.It was concluded from these findings that the macrophages accelerated the phagocytotic activity of the virus particles.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01025.x

年代:1977

数据来源: WILEY

摘要:

ABSTRACTIn rat skin of both sexes, significantly higher concentrations of mast cells were observed in the genital area as compared with the skin of the back. The hydroxyproline (HPL) value in the preputial skin was half that in the dorsal skin. The influence of castration and the administration of testosterone on male rat skin mast cells and HPL were investigated. A possible relationship was pointed out between HPL value and the mast cell population of the skin.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01026.x

年代:1977

数据来源: WILEY

摘要:

ABSTRACTOf sebaceous gland‐containing specimens of melanocytic nevi, a total of 79 specimens from 70 cases of nevocellular nevus (consisting of 10 cases of compound nevus and 60 of intradermal nevus), four cases of juvenile melanoma and three of blue nevus were examined light‐microscopically in detail for the presence or absence of nevus cells or dermal melanocytes in the sebaceous glands. As a result, clusters of cells that appeared to be nevus cells were found in the sebaceous glands of specimens from a total of three cases, that is, two cases of nevocellular nevus i.e. compound nevus, and one of the cases of juvenile melanoma. Two cases were infantile and one case was the age of puberty. The origin of the nevus cells found in the sebaceous glands is discus

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01027.x

年代:1977

数据来源: WILEY

摘要:

ABSTRACTThe case of a 10 year‐old Japanese boy with erythrokeratodermia variabilis is reported in addition to a review of the Japanese literature. The patient was first examined in our clinic on October 21, 1965, because of generalized hyperkeratotic lesions and erythematous lesions which had persisted since he was 3 months old. Hyperkeratotic and verrucous lesions were noted on his auricles and trunk, on which there were also sharply demarcated erythematous lesions of various sizes and shapes which were not elevated from the adjacent skin. Laboratory findings were within normal limits. Histopathological examination revealed a remarkable hyperkeratosis with a basket weave appearance, moderate acanthosis and a slightly thickened granular layer. Polyethylenglycol 400 and corticosteroid ointment were slightly beneficial to the hyperkeratotic lesion

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01028.x

年代:1977

数据来源: WILEY

摘要:

ABSTRACTPurine phosphoribosyltransferase activities in normal and experimental hyperkeratotic epidermis of guinea pig skin were demonstrated quantitatively by a new microassay method.The ratio of HGPRTase with hypoxanthine as a substrate to APRTase activity in normal and hyperkeratotic epidermis was found to be 0.94 and 0.60, respectively. The HGPRTase and APRTase activities expressed as μmoles per gram wet weight per min. were increased in experimental hyperkeratotic epidermis and it is suggested that the salvage pathway for purine nucleotide biosynthesis is activated in experimental hyperkeratotic epidermis.The pH optimum of these enzymes and their stability in the frozen state were also demonstrated

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01029.x

年代:1977

数据来源: WILEY

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01030.x

年代:1977

数据来源: WILEY

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01031.x

年代:1977

数据来源: WILEY

摘要:

RECENT ADVANCES IN MEDICAL AND VETERINARY MYCOLOGY: Kazuo Iwata, M.D. (ed.) University of Tokyo Press, Tokyo, 1977. (Pp. 316, ¥12000

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1977.tb01032.x

年代:1977

数据来源: WILEY